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> Protein (NX_Q86TG7)
Protein (NX_Q86TG7)
Protein
Gene SymbolPEG10 to neXtProt (NX_Q86TG7)
DescriptionRetrotransposon-derived protein PEG10
Chromosome7
Location7q21.3 (94285637 ~ 94299007) to Ensembl
Sequene Features : Isoforms 2, Variants 45, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of transforming growth factor beta receptor signaling pathway
.cell differentiation
.apoptotic process
.poly(A) RNA binding
.zinc ion binding
.DNA binding
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 45 5
2014-09-19protein level
2 28 5
2014-05-27protein level
2 28 5
2014-02-25protein level
2 28 5
2013-12-09protein level
2 23 5
2013-11-01protein level
2 23 4
2013-09-12protein level
2 23 4
2013-08-17protein level
2 23 4
2013-07-15protein level
2 18 4
2013-06-11protein level
2 18 4
2013-02-12protein level
2 3 3
2012-12-20protein level
2 6 3
2012-10-30protein level
2 6 3
2012-10-07protein level
2 6 3
2012-08-24protein level
2 4 3
2012-07-28protein level
2 4 3
2012-06-08protein level
2 1 3
2012-05-07protein level
2 1 3
2012-04-10protein level
2 1 3
2012-01-13protein level
2 1 3
2011-12-20protein level
2 1 3
2011-11-11protein level
2 1 1
2011-08-23protein level
2 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86TG7-1
16 13 0 80121.7491
NX_Q86TG7-2
1 13 0 36942.1365
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2858265,EBI-10174072 FAM127A  
  .N/A .N/A .N/A
2 EBI-2858265,EBI-740738 LDOC1  
  .negative regulation of cell proliferation .N/A .nucleolus
.nucleus
3 EBI-2858265,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
4 EBI-2858265,EBI-10238588 FAM127C  
  .N/A .N/A .N/A
5 EBI-2858265,EBI-747107 SIAH1  
  .positive regulation of intrinsic apoptotic signaling pathway
.neuron apoptotic process
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 11 more...
.ubiquitin protein ligase activity
.identical protein binding
.ligase activity
  + 3 more...
.beta-catenin destruction complex
.plasma membrane
.cytosol
  + 3 more...
6 EBI-2858265,EBI-74615 TOLLIP  
  .leukocyte activation
.innate immune response
.protein localization to endosome
  + 8 more...
.Toll-like receptor binding
.kinase binding
.signal transducer activity
.extracellular exosome
.perinuclear region of cytoplasm
.interleukin-1 receptor complex
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland242
ascites25
bladder33
bone marrow20
brain107
connective tissue13
ear124
embryonic tissue244
eye52
heart390
intestine12
kidney66
liver175
lung86
lymph22
lymph node33
mammary gland132
mouth166
muscle75
nerve257
ovary19
pancreas60
pituitary gland605
placenta459
prostate5
skin109
stomach10
testis87
thyroid42
trachea19
umbilical cord145
uterus21
vascular58
Health State
TissuesTPM*
normal142
adrenal tumor237
bladder carcinoma56
breast (mammary gland) tumor171
chondrosarcoma24
colorectal tumor17
gastrointestinal tumor8
germ cell tumor94
glioma83
head and neck tumor97
kidney tumor130
leukemia10
liver tumor343
lung tumor9
lymphoma55
non-neoplasia31
ovarian tumor26
pancreatic tumor47
prostate cancer9
retinoblastoma107
skin tumor79
soft tissue/muscle tissue tumor31
uterine tumor11
Developmental Stage
TissuesTPM*
adult122
embryoid body257
blastocyst179
neonate128
fetus249
juvenile251
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.7
adrenal gland176
appendix3.1
cerebral cortex41
colon2
esophagus2.2
gallbladder3.4
heart muscle1.3
kidney8.8
lung13.2
lymph node5.1
ovary59.3
pancreas5.1
placenta370.9
prostate2.7
salivary gland6.8
small intestine1.4
spleen2
stomach3
testis44.2
thyroid gland12.1
urinary bladder2.1
Tissues
TissuesExpression level
adrenal glandMedium
bronchusLow
placentaHigh
testisLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609810, gene) Paternally expressed gene 10; PEG10OMIM


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