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> Protein (NX_Q86U06)
Protein (NX_Q86U06)
Protein
Gene SymbolRBM23 to neXtProt (NX_Q86U06)
DescriptionProbable RNA-binding protein 23
Chromosome14
Location14q11.2 (23369854 ~ 23388393) to Ensembl
Sequene Features : Isoforms 5, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mRNA processing .RNA binding
.nucleotide binding
.membrane
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 65 4
2014-09-19protein level
5 55 4
2014-05-27protein level
5 55 4
2014-02-25protein level
5 55 4
2013-12-09protein level
5 31 4
2013-11-01protein level
5 31 4
2013-09-12protein level
5 31 4
2013-08-17protein level
5 31 4
2013-07-15protein level
5 22 3
2013-06-11protein level
5 22 3
2013-02-12protein level
5 9 8
2012-12-20protein level
5 11 8
2012-10-30protein level
5 19 8
2012-10-07protein level
5 19 2
2012-08-24protein level
5 18 2
2012-07-28protein level
5 15 2
2012-06-08protein level
5 5 2
2012-05-07protein level
5 5 2
2012-04-10protein level
5 5 2
2012-01-13protein level
5 5 2
2011-12-20protein level
5 5 2
2011-11-11protein level
5 5 1
2011-08-23protein level
5 5 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86U06-1
0 14 2 48700.5769
NX_Q86U06-2
0 14 2 46679.3895
NX_Q86U06-3
1 10 2 36512.5337
NX_Q86U06-4
1 12 2 44467.2558
NX_Q86U06-5
2 12 2 44902.286
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-780319,EBI-711810 BHLHE40  
  .negative regulation of transcription, DNA-templated
.negative regulation of sequence-specific DNA binding transcription factor activity
.entrainment of circadian clock by photoperiod
  + 4 more...
.E-box binding
.protein heterodimerization activity
.MRF binding
  + 10 more...
.Golgi apparatus
.nucleolus
.nucleoplasm
.nucleus
2 EBI-780319,EBI-351098 PRMT5  
  .histone H4-R3 methylation
.endothelial cell activation
.peptidyl-arginine N-methylation
  + 12 more...
.protein heterodimerization activity
.ribonucleoprotein complex binding
.protein-arginine omega-N symmetric methyltransferase activity
  + 5 more...
.methylosome
.cytosol
.cytoplasm
  + 2 more...
3 EBI-780319,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
4 EBI-780319,EBI-10178634 MAGEA11  
  .N/A .N/A .cytoplasm
.nucleoplasm
.nucleus
5 EBI-780319,EBI-593303 SRPK2  
  .regulation of mRNA splicing, via spliceosome
.positive regulation of cell cycle
.innate immune response
  + 12 more...
.14-3-3 protein binding
.poly(A) RNA binding
.ATP binding
  + 2 more...
.cytoplasm
.nucleolus
.nucleoplasm
.nucleus
6 EBI-780319,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
7 EBI-780319,EBI-716006 MAGED1  
  .positive regulation of apoptotic signaling pathway
.extrinsic apoptotic signaling pathway in absence of ligand
.extrinsic apoptotic signaling pathway
  + 15 more...
.transcription coactivator activity .protein complex
.plasma membrane
.cytoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland182
ascites125
bladder66
blood196
bone139
bone marrow102
brain86
cervix61
connective tissue60
ear62
embryonic tissue75
esophagus148
eye172
heart78
intestine73
kidney61
larynx85
liver58
lung116
lymph90
lymph node77
mammary gland119
mouth362
muscle150
nerve64
ovary128
pancreas131
parathyroid48
pharynx73
placenta204
prostate63
salivary gland246
skin94
spleen112
stomach94
testis85
thymus112
thyroid150
trachea57
umbilical cord145
uterus90
vascular96
Health State
TissuesTPM*
normal102
adrenal tumor316
breast (mammary gland) tumor150
cervical tumor86
chondrosarcoma181
colorectal tumor79
esophageal tumor115
gastrointestinal tumor101
germ cell tumor132
glioma158
head and neck tumor246
kidney tumor87
leukemia148
liver tumor41
lung tumor107
lymphoma55
non-neoplasia31
ovarian tumor105
pancreatic tumor123
primitive neuroectodermal tumor of the CNS196
prostate cancer86
retinoblastoma86
skin tumor47
soft tissue/muscle tissue tumor127
uterine tumor77
Developmental Stage
TissuesTPM*
adult110
embryoid body57
blastocyst146
neonate128
fetus70
infant42
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue24.7
adrenal gland36.1
appendix36.2
bone marrow42.2
cerebral cortex28.9
colon31.9
duodenum27
esophagus37.5
gallbladder39.3
heart muscle25.4
kidney37.4
liver18.1
lung39.9
lymph node42.9
ovary54.1
pancreas19.5
placenta41.8
prostate33.7
salivary gland27.3
skin31
small intestine30.2
spleen38.5
stomach30.3
testis34.1
thyroid gland59.3
urinary bladder42.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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