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> Protein (NX_Q86U42)
Protein (NX_Q86U42)
Protein
Gene SymbolPABPN1 to neXtProt (NX_Q86U42)
DescriptionPolyadenylate-binding protein 2
Chromosome14
Location14q11.2 (23790498 ~ 23795394) to Ensembl
Sequene Features : Isoforms 2, Variants 25, PTMs 21 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.modification by virus of host mRNA processing
.mRNA 3'-end processing
.viral life cycle
  + 10 more...
.poly(A) RNA binding
.RNA binding
.nucleotide binding
.ribonucleoprotein complex
.cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 25 21
2014-09-19protein level
2 20 21
2014-05-27protein level
2 20 28
2014-02-25protein level
2 20 26
2013-12-09protein level
2 14 26
2013-11-01protein level
2 14 25
2013-09-12protein level
2 14 25
2013-08-17protein level
2 14 25
2013-07-15protein level
2 6 22
2013-06-11protein level
2 6 22
2013-02-12protein level
2 5 37
2012-12-20protein level
2 6 37
2012-10-30protein level
2 6 37
2012-10-07protein level
2 6 20
2012-08-24protein level
2 6 20
2012-07-28protein level
2 6 20
2012-06-08protein level
2 8 20
2012-05-07protein level
2 6 20
2012-04-10protein level
2 6 20
2012-01-13protein level
2 5 20
2011-12-20protein level
2 5 20
2011-11-11protein level
2 5 19
2011-08-23protein level
2 5 19
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86U42-1
0 3 10 32728.8991
NX_Q86U42-2
0 3 9 31477.2877
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1226435,EBI-632715 SNW1  
  .cellular response to retinoic acid
.positive regulation of vitamin D receptor signaling pathway
.regulation of vitamin D receptor signaling pathway
  + 19 more...
.SMAD binding
.poly(A) RNA binding
.retinoic acid receptor binding
  + 5 more...
.catalytic step 2 spliceosome
.nuclear matrix
.spliceosomal complex
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland91
ascites251
bladder167
blood81
bone27
bone marrow61
brain54
cervix144
connective tissue33
embryonic tissue140
esophagus99
eye76
heart89
intestine64
kidney47
larynx42
liver68
lung80
lymph135
lymph node66
mammary gland105
mouth136
muscle18
nerve193
ovary98
pancreas70
placenta77
prostate79
salivary gland148
skin61
stomach52
testis87
thymus12
thyroid150
tonsil58
uterus68
Health State
TissuesTPM*
normal69
adrenal tumor79
bladder carcinoma113
breast (mammary gland) tumor85
cervical tumor115
chondrosarcoma72
colorectal tumor88
esophageal tumor115
gastrointestinal tumor109
germ cell tumor60
glioma111
head and neck tumor127
kidney tumor87
leukemia105
liver tumor83
lung tumor68
lymphoma138
non-neoplasia31
ovarian tumor52
pancreatic tumor47
primitive neuroectodermal tumor of the CNS62
prostate cancer28
retinoblastoma107
skin tumor47
soft tissue/muscle tissue tumor39
uterine tumor66
Developmental Stage
TissuesTPM*
adult90
embryoid body171
blastocyst81
fetus84
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue54.8
adrenal gland60.2
appendix59.6
bone marrow62.8
cerebral cortex49.1
colon52.7
duodenum75.5
esophagus40.4
gallbladder51
heart muscle39.1
kidney47.2
liver32.2
lung55.9
lymph node69.7
ovary56
pancreas22.3
placenta51
prostate64.5
salivary gland45.8
skin70.2
small intestine64.5
spleen69.6
stomach51.6
testis88.2
thyroid gland51.5
urinary bladder43.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#164300, phenotype) Oculopharyngeal muscular dystrophy; OPMDOMIM
2(*602279, gene) Polyadenylate-binding protein, nuclear, 1; PABPN1OMIM


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