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> Protein (NX_Q86UV6)
Protein (NX_Q86UV6)
Protein
Gene SymbolTRIM74 to neXtProt (NX_Q86UV6)
DescriptionTripartite motif-containing protein 74
Chromosome7
Location7q11.23 (72430016 ~ 72439997) to Ensembl
Sequene Features : Isoforms 2, Variants 9, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .zinc ion binding .intracellular
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
2 9 0
2014-09-19transcript level
2 7 0
2014-05-27transcript level
2 7 0
2014-02-25transcript level
2 7 0
2013-12-09transcript level
2 7 0
2013-11-01transcript level
2 7 0
2013-09-12transcript level
2 7 0
2013-08-17transcript level
2 7 0
2013-07-15transcript level
2 6 0
2013-06-11transcript level
2 6 0
2013-02-12transcript level
2 4 0
2012-12-20transcript level
2 4 0
2012-10-30transcript level
2 3 0
2012-10-07transcript level
2 3 0
2012-08-24transcript level
2 3 0
2012-07-28transcript level
2 3 0
2012-06-08transcript level
2 5 0
2012-05-07transcript level
2 5 0
2012-04-10transcript level
2 5 0
2012-01-13transcript level
2 3 0
2011-12-20transcript level
2 3 0
2011-11-11transcript level
2 3 0
2011-08-23transcript level
2 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86UV6-1
0 0 12 28528.1231
NX_Q86UV6-2
1 0 11 28400.0286
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10259086,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
brain5
embryonic tissue4
lung2
mouth15
testis4
uterus4
Health State
TissuesTPM*
normal2
gastrointestinal tumor8
head and neck tumor7
non-neoplasia41
Developmental Stage
TissuesTPM*
adult4
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
duodenum1.4
lung1
lymph node1.3
pancreas2.6
prostate1.2
skin1.1
stomach6.2
testis4.6
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*612550, gene) Tripartite motif-containing protein 74; TRIM74OMIM


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