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> Protein (NX_Q86V24)
Protein (NX_Q86V24)
Protein
Gene SymbolADIPOR2 to neXtProt (NX_Q86V24)
DescriptionAdiponectin receptor protein 2
Chromosome12
Location12p13.33 (1797740 ~ 1897844) to Ensembl
Sequene Features : Isoforms 1, Variants 41, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of glucose import
.adiponectin-activated signaling pathway
.negative regulation of cell growth
  + 5 more...
.hormone binding
.receptor activity
.integral component of membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 41 0
2014-09-19protein level
1 30 0
2014-05-27protein level
1 30 0
2014-02-25protein level
1 30 0
2013-12-09protein level
1 24 0
2013-11-01protein level
1 24 0
2013-09-12protein level
1 24 0
2013-08-17protein level
1 24 0
2013-07-15protein level
1 16 0
2013-06-11protein level
1 16 0
2013-02-12protein level
1 6 0
2012-12-20protein level
1 7 0
2012-10-30protein level
1 8 0
2012-10-07protein level
1 8 0
2012-08-24protein level
1 8 0
2012-07-28protein level
1 8 0
2012-06-08protein level
1 9 0
2012-05-07protein level
1 6 0
2012-04-10protein level
1 6 0
2012-01-13protein level
1 6 0
2011-12-20protein level
1 6 0
2011-11-11protein level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86V24-1
13 0 0 43854.7536
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1769445,EBI-741243 APPL1  
  .extrinsic apoptotic signaling pathway in absence of ligand
.extrinsic apoptotic signaling pathway
.regulation of establishment of protein localization to plasma membrane
  + 7 more...
.protein kinase B binding
.identical protein binding
.extracellular exosome
.early endosome membrane
.vesicle membrane
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland151
ascites125
bladder66
blood24
bone83
bone marrow20
brain113
cervix164
connective tissue53
ear124
embryonic tissue75
eye81
heart67
intestine99
kidney71
larynx42
liver92
lung101
lymph564
lymph node66
mammary gland85
mouth45
muscle141
nerve257
ovary88
pancreas65
placenta28
prostate58
skin142
stomach41
testis110
thymus75
thyroid171
trachea115
uterus86
Health State
TissuesTPM*
normal67
adrenal tumor237
bladder carcinoma170
breast (mammary gland) tumor118
cervical tumor231
chondrosarcoma120
colorectal tumor115
gastrointestinal tumor101
germ cell tumor167
glioma18
head and neck tumor74
kidney tumor116
leukemia31
liver tumor135
lung tumor165
lymphoma346
non-neoplasia20
ovarian tumor105
pancreatic tumor95
primitive neuroectodermal tumor of the CNS110
prostate cancer67
retinoblastoma64
skin tumor183
soft tissue/muscle tissue tumor191
uterine tumor66
Developmental Stage
TissuesTPM*
adult69
embryoid body85
blastocyst81
neonate32
fetus52
infant42
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue59.9
adrenal gland56.3
appendix22.3
bone marrow12.7
cerebral cortex41.2
colon34.9
duodenum38.8
esophagus42.8
gallbladder22.1
heart muscle20.8
kidney21.2
liver53.9
lung25.3
lymph node19.5
ovary22.3
pancreas27.5
placenta20.4
prostate20.2
salivary gland14.7
skin22.3
small intestine35.5
spleen16.1
stomach42
testis34.7
thyroid gland36.2
urinary bladder16.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607946, gene) Adiponectin receptor 2; ADIPOR2OMIM


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