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> Protein (NX_Q86VR2)
Protein (NX_Q86VR2)
Protein
Gene SymbolFAM134C to neXtProt (NX_Q86VR2)
DescriptionProtein FAM134C
Chromosome17
Location17q21.2 (40731531 ~ 40762641) to Ensembl
Sequene Features : Isoforms 2, Variants 53, PTMs 19 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .integral component of membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 53 19
2014-09-19protein level
1 41 19
2014-05-27protein level
1 41 19
2014-02-25protein level
1 41 19
2013-12-09protein level
1 33 19
2013-11-01protein level
1 31 18
2013-09-12protein level
1 31 16
2013-08-17protein level
1 31 16
2013-07-15protein level
1 26 16
2013-06-11protein level
1 26 16
2013-02-12protein level
1 19 22
2012-12-20protein level
1 18 22
2012-10-30protein level
1 20 22
2012-10-07protein level
1 20 22
2012-08-24protein level
1 16 22
2012-07-28protein level
1 16 22
2012-06-08protein level
1 16 22
2012-05-07protein level
1 16 22
2012-04-10protein level
1 16 22
2012-01-13protein level
1 2 22
2011-12-20protein level
1 2 22
2011-11-11protein level
1 2 20
2011-08-23protein level
1 2 20
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86VR2-1
11 7 0 51363.5933
NX_Q86VR2-2
1 7 0 29563.0919
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10192441,EBI-348517 ABHD16A  
  .N/A .hydrolase activity .integral component of membrane
2 EBI-10192441,EBI-714543 ARL6IP1  
  .cotranslational protein targeting to membrane .N/A .integral component of membrane
.membrane
.cytosol
.Sec61 translocon complex
3 EBI-10192441,EBI-3464833 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
4 EBI-10192441,EBI-720768 MAP1LC3A  
  .membrane fusion
.nucleophagy
.cellular response to nitrogen starvation
  + 2 more...
.phosphatidylethanolamine binding
.microtubule binding
.phospholipid binding
.cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 6 more...
5 EBI-10192441,EBI-6083058 STAP1  
  .positive regulation of actin cytoskeleton reorganization
.positive regulation of non-membrane spanning protein tyrosine kinase activity
.positive regulation of microglial cell activation
  + 10 more...
.protein kinase binding
.phospholipid binding
.SH3/SH2 adaptor activity
  + 2 more...
.protein complex
.mitochondrion
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
bladder33
blood57
bone41
brain100
cervix20
connective tissue20
embryonic tissue28
eye76
heart33
intestine21
kidney52
larynx127
liver34
lung71
lymph67
lymph node33
mammary gland99
mouth241
muscle28
nerve64
ovary29
pancreas37
parathyroid242
pharynx49
placenta137
prostate26
skin99
spleen18
stomach20
testis181
thymus112
thyroid21
trachea444
umbilical cord290
uterus137
vascular19
Health State
TissuesTPM*
normal71
breast (mammary gland) tumor53
cervical tumor28
chondrosarcoma60
colorectal tumor26
gastrointestinal tumor33
germ cell tumor64
glioma27
head and neck tumor149
leukemia31
liver tumor72
lung tumor58
lymphoma41
non-neoplasia41
ovarian tumor26
pancreatic tumor76
primitive neuroectodermal tumor of the CNS31
prostate cancer9
retinoblastoma21
skin tumor151
soft tissue/muscle tissue tumor23
uterine tumor44
Developmental Stage
TissuesTPM*
adult66
embryoid body14
blastocyst48
neonate32
fetus71
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue15.7
adrenal gland14.4
appendix18.7
bone marrow6.1
cerebral cortex14.6
colon17
duodenum14.3
esophagus16.7
gallbladder14.1
heart muscle9.7
kidney15.9
liver13.5
lung21.4
lymph node22.1
ovary20.2
pancreas18.9
placenta22.7
prostate20
salivary gland17
skin29.4
small intestine13.7
spleen25.9
stomach20.7
testis31.2
thyroid gland15.3
urinary bladder16
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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