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> Protein (NX_Q86VV8)
Protein (NX_Q86VV8)
Protein
Gene SymbolRTTN to neXtProt (NX_Q86VV8)
DescriptionRotatin
Chromosome18
Location18q22.2 (67671029 ~ 67873181) to Ensembl
Sequene Features : Isoforms 4, Variants 258, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.determination of left/right symmetry .N/A .ciliary basal body
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 258 2
2014-09-19protein level
4 208 2
2014-05-27protein level
4 208 2
2014-02-25protein level
4 207 2
2013-12-09protein level
4 145 2
2013-11-01protein level
4 140 2
2013-09-12protein level
4 140 2
2013-08-17protein level
4 140 2
2013-07-15protein level
4 96 1
2013-06-11protein level
4 96 1
2013-02-12protein level
4 39 3
2012-12-20protein level
4 35 3
2012-10-30protein level
4 58 3
2012-10-07protein level
4 58 1
2012-08-24protein level
4 46 1
2012-07-28protein level
4 46 1
2012-06-08protein level
4 12 1
2012-05-07protein level
4 12 1
2012-04-10protein level
4 12 1
2012-01-13protein level
5 12 1
2011-12-20protein level
5 13 1
2011-11-11protein level
5 13 1
2011-08-23protein level
5 13 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86VV8-1
2 99 0 248469.2209
NX_Q86VV8-2
0 30 0 67645.5384
NX_Q86VV8-3
0 99 0 245530.7755
NX_Q86VV8-4
2 42 0 98872.0231
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood32
bone13
brain9
cervix20
connective tissue6
embryonic tissue32
eye19
heart11
intestine8
kidney23
lung11
lymph22
lymph node11
mammary gland39
muscle28
nerve64
pancreas9
placenta14
prostate26
skin18
spleen18
testis27
thyroid107
trachea19
uterus25
Health State
TissuesTPM*
normal20
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma24
colorectal tumor8
germ cell tumor18
head and neck tumor37
kidney tumor43
leukemia42
lung tumor29
lymphoma27
non-neoplasia20
pancreatic tumor19
prostate cancer19
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor31
uterine tumor11
Developmental Stage
TissuesTPM*
adult19
embryoid body28
blastocyst32
fetus34
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.6
adrenal gland2.5
appendix3.6
bone marrow5.2
cerebral cortex3.3
colon2.9
duodenum2.8
esophagus2.1
gallbladder3.2
heart muscle4
kidney6
liver5
lung3.6
lymph node5.7
ovary6.3
pancreas1
placenta3.1
prostate3.7
salivary gland2.8
skin2.7
small intestine2.2
spleen3.9
stomach2.2
testis8.6
thyroid gland2.8
urinary bladder2.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610436, gene) Rotatin; RTTNOMIM
2(#614833, phenotype) Polymicrogyria with seizures; PMGYSOMIM


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