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> Protein (NX_Q86WP2)
Protein (NX_Q86WP2)
Protein
Gene SymbolGPBP1 to neXtProt (NX_Q86WP2)
DescriptionVasculin
Chromosome5
Location5q11.2 (56469775 ~ 56560506) to Ensembl
Sequene Features : Isoforms 4, Variants 69, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of transcription, DNA-templated
.transcription, DNA-templated
.sequence-specific DNA binding transcription factor activity
.DNA binding
.intracellular membrane-bounded organelle
.plasma membrane
.cytoplasm
.nucleolus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 69 5
2014-09-19protein level
4 51 5
2014-05-27protein level
4 51 5
2014-02-25protein level
4 51 4
2013-12-09protein level
4 47 4
2013-11-01protein level
4 44 4
2013-09-12protein level
4 44 4
2013-08-17protein level
4 44 4
2013-07-15protein level
4 27 4
2013-06-11protein level
4 27 4
2013-02-12protein level
4 13 3
2012-12-20protein level
4 13 3
2012-10-30protein level
4 15 3
2012-10-07protein level
4 15 1
2012-08-24protein level
4 14 1
2012-07-28protein level
4 14 1
2012-06-08protein level
4 16 1
2012-05-07protein level
4 10 1
2012-04-10protein level
4 10 1
2012-01-13protein level
4 8 1
2011-12-20protein level
4 8 1
2011-11-11protein level
4 8 1
2011-08-23protein level
4 8 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86WP2-1
0 23 0 53306.7781
NX_Q86WP2-2
0 23 0 54035.2191
NX_Q86WP2-3
0 22 0 52405.4709
NX_Q86WP2-4
0 14 0 33809.4652
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2349758,EBI-744935 C20orf195  
  .N/A .N/A .extracellular exosome
2 EBI-2349758,EBI-742388 PLEKHF2  
  .protein transport .metal ion binding .early endosome membrane
.transport vesicle
.endoplasmic reticulum
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland121
ascites75
bladder133
blood114
bone83
bone marrow61
brain156
cervix123
connective tissue53
ear124
embryonic tissue136
esophagus49
eye114
heart89
intestine68
kidney75
larynx170
liver102
lung134
lymph45
lymph node200
mammary gland119
mouth105
muscle282
nerve257
ovary39
pancreas18
parathyroid145
pharynx122
pituitary gland60
placenta127
prostate42
skin61
spleen37
stomach480
testis307
thymus238
thyroid85
trachea231
uterus129
vascular116
Health State
TissuesTPM*
normal148
adrenal tumor158
bladder carcinoma113
breast (mammary gland) tumor171
cervical tumor144
chondrosarcoma72
colorectal tumor62
esophageal tumor57
gastrointestinal tumor354
germ cell tumor174
glioma37
head and neck tumor97
kidney tumor14
leukemia116
liver tumor41
lung tumor48
lymphoma110
non-neoplasia103
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS55
prostate cancer28
retinoblastoma64
skin tumor39
soft tissue/muscle tissue tumor63
uterine tumor110
Developmental Stage
TissuesTPM*
adult137
embryoid body185
blastocyst97
neonate96
fetus170
infant85
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue33
adrenal gland56
appendix45.9
bone marrow50.5
cerebral cortex43.1
colon37.7
duodenum33.6
esophagus37.1
gallbladder45.3
heart muscle28.7
kidney36
liver24.9
lung42.4
lymph node62.8
ovary71.6
pancreas18.9
placenta45.7
prostate37.7
salivary gland36.7
skin41.2
small intestine37.2
spleen44
stomach38.9
testis80.4
thyroid gland57.5
urinary bladder45.6
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumMedium
endometrium 1Medium
endometrium 2High
epididymisMedium
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverMedium
lungLow
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
pancreasHigh
parathyroid glandMedium
placentaMedium
prostateMedium
rectumHigh
salivary glandLow
seminal vesicleMedium
skeletal muscleMedium
skin 1High
skin 2Medium
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2High
spleenLow
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilMedium
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608412, gene) Gc-rich promoter-binding protein 1; GPBP1OMIM


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