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> Protein (NX_Q86WZ6)
Protein (NX_Q86WZ6)
Protein
Gene SymbolZNF227 to neXtProt (NX_Q86WZ6)
DescriptionZinc finger protein 227
Chromosome19
Location19q13.31 (44711700 ~ 44741421) to Ensembl
Sequene Features : Isoforms 2, Variants 101, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 101 0
2014-09-19protein level
1 76 0
2014-05-27transcript level
1 76 2
2014-02-25transcript level
1 76 2
2013-12-09transcript level
1 53 2
2013-11-01transcript level
1 51 2
2013-09-12transcript level
1 51 2
2013-08-17protein level
1 51 2
2013-07-15protein level
1 32 0
2013-06-11protein level
1 32 0
2013-02-12protein level
1 13 0
2012-12-20protein level
1 12 0
2012-10-30protein level
1 21 0
2012-10-07protein level
1 21 0
2012-08-24transcript level
1 21 0
2012-07-28transcript level
1 21 0
2012-06-08transcript level
1 21 0
2012-05-07transcript level
1 17 0
2012-04-10transcript level
1 17 0
2012-01-13transcript level
1 6 0
2011-12-20transcript level
1 6 0
2011-11-11transcript level
1 6 0
2011-08-23transcript level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86WZ6-1
3 31 13 91973.3466
NX_Q86WZ6-2
0 31 12 85833.13
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2799529,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
blood16
bone13
brain14
cervix20
embryonic tissue32
intestine17
kidney4
liver4
lung8
lymph node33
mammary gland26
mouth15
muscle18
pancreas9
parathyroid97
placenta10
prostate15
skin9
stomach10
testis25
thymus163
trachea19
uterus21
vascular19
Health State
TissuesTPM*
normal18
breast (mammary gland) tumor21
cervical tumor28
colorectal tumor8
gastrointestinal tumor8
germ cell tumor30
glioma18
head and neck tumor7
leukemia10
liver tumor10
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult12
embryoid body14
blastocyst32
neonate32
fetus17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.1
adrenal gland8.2
appendix7.3
bone marrow3.5
cerebral cortex7.7
colon6.5
duodenum5.5
esophagus7.1
gallbladder7.2
heart muscle5.8
kidney7.6
liver5.5
lung7.3
lymph node11.3
ovary11.8
pancreas3.1
placenta7.6
prostate9.5
salivary gland4.3
skin6.2
small intestine5.3
spleen10.1
stomach9.1
testis9.1
thyroid gland9.7
urinary bladder10.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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