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> Protein (NX_Q86X52)
Protein (NX_Q86X52)
Protein
Gene SymbolCHSY1 to neXtProt (NX_Q86X52)
DescriptionChondroitin sulfate synthase 1
Chromosome15
Location15q26.3 (101715928 ~ 101792137) to Ensembl
Sequene Features : Isoforms 1, Variants 83, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.bone morphogenesis
.sulfation
.positive regulation of smoothened signaling pathway
  + 9 more...
.N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
.glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
.metal ion binding
.Golgi cisterna membrane
.integral component of membrane
.membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 83 5
2014-09-19protein level
1 59 5
2014-05-27protein level
1 59 5
2014-02-25protein level
1 59 5
2013-12-09protein level
1 52 5
2013-11-01protein level
1 50 5
2013-09-12protein level
1 50 5
2013-08-17protein level
1 50 5
2013-07-15protein level
1 32 3
2013-06-11protein level
1 32 3
2013-02-12protein level
1 20 3
2012-12-20protein level
1 20 3
2012-10-30protein level
1 22 3
2012-10-07protein level
1 22 3
2012-08-24protein level
1 20 3
2012-07-28protein level
1 20 3
2012-06-08protein level
1 22 3
2012-05-07protein level
1 22 3
2012-04-10protein level
1 22 3
2012-01-13protein level
1 13 3
2011-12-20protein level
1 13 3
2011-11-11protein level
1 13 3
2011-08-23protein level
1 11 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86X52-1
33 0 3 91725.4715
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder100
blood40
bone69
bone marrow61
brain15
cervix20
connective tissue73
ear124
embryonic tissue23
eye14
heart33
intestine30
kidney14
larynx42
liver9
lung17
lymph node77
mammary gland6
mouth256
muscle28
ovary19
pancreas42
placenta123
prostate15
skin47
spleen56
stomach41
testis22
thymus37
thyroid42
uterus43
vascular77
Health State
TissuesTPM*
normal33
adrenal tumor79
cervical tumor28
chondrosarcoma96
colorectal tumor53
gastrointestinal tumor16
germ cell tumor26
glioma18
head and neck tumor127
kidney tumor14
leukemia31
liver tumor20
lung tumor19
lymphoma13
non-neoplasia10
ovarian tumor26
pancreatic tumor38
primitive neuroectodermal tumor of the CNS31
prostate cancer9
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult53
embryoid body42
blastocyst16
neonate32
fetus14
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue33.2
adrenal gland26.1
appendix28.4
bone marrow22.4
cerebral cortex8
colon12.5
duodenum7
esophagus18.2
gallbladder41.3
heart muscle12.6
kidney10.9
liver8.6
lung21.2
lymph node17.8
ovary20
pancreas5.6
placenta62.8
prostate17.8
salivary gland10.3
skin13
small intestine8.4
spleen17.2
stomach11.1
testis15
thyroid gland11.4
urinary bladder33.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#605282, phenotype) Temtamy preaxial brachydactyly syndrome; TPBSOMIM
2(*608183, gene) Chondroitin sulfate synthase 1; CHSY1OMIM


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