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> Protein (NX_Q86Y13)
Protein (NX_Q86Y13)
Protein
Gene SymbolDZIP3 to neXtProt (NX_Q86Y13)
DescriptionE3 ubiquitin-protein ligase DZIP3
Chromosome3
Location3q13.13 (108308529 ~ 108413693) to Ensembl
Sequene Features : Isoforms 2, Variants 164, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein polyubiquitination .poly(A) RNA binding
.polyubiquitin binding
.phosphatase binding
  + 4 more...
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 164 4
2014-09-19protein level
2 129 4
2014-05-27protein level
2 129 4
2014-02-25protein level
2 129 4
2013-12-09protein level
2 93 4
2013-11-01protein level
2 89 2
2013-09-12protein level
2 89 2
2013-08-17protein level
2 89 2
2013-07-15protein level
2 55 1
2013-06-11protein level
2 55 1
2013-02-12protein level
2 24 1
2012-12-20protein level
2 25 1
2012-10-30protein level
2 36 1
2012-10-07protein level
2 36 1
2012-08-24protein level
2 33 1
2012-07-28protein level
2 32 1
2012-06-08protein level
2 35 1
2012-05-07protein level
2 26 1
2012-04-10protein level
2 26 1
2012-01-13protein level
2 13 1
2011-12-20protein level
2 13 1
2011-11-11protein level
2 13 1
2011-08-23protein level
2 13 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86Y13-1
43 19 0 138515.4943
NX_Q86Y13-2
0 19 0 35217.583
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-948630,EBI-308663 ARHGAP32  
  .regulation of small GTPase mediated signal transduction
.small GTPase mediated signal transduction
.phosphatidylinositol binding
.GTPase activator activity
.postsynaptic membrane
.dendritic spine
.cell junction
  + 7 more...
2 EBI-948630,EBI-707773 ZNF24  
  .negative regulation of transcription, DNA-templated
.myelination
.transcription, DNA-templated
.sequence-specific DNA binding
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleoplasm
.nucleus
3 EBI-948630,EBI-352986 HNRNPF  
  .regulation of RNA splicing
.gene expression
.RNA splicing
  + 2 more...
.poly(A) RNA binding
.single-stranded RNA binding
.RNA binding
.nucleotide binding
.catalytic step 2 spliceosome
.membrane
.nucleoplasm
.nucleus
4 EBI-948630,EBI-8469755 GTF2H2C  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.nucleotide-excision repair
.zinc ion binding .core TFIIH complex
5 EBI-948630,EBI-9676069 ZNF765  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
6 EBI-948630,EBI-597063 ZCCHC10  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
7 EBI-948630,EBI-741977 CEP63  
  .cell division
.spindle assembly
.signal transduction in response to DNA damage
  + 6 more...
.N/A .cytosol
.centriole
.centrosome
.spindle pole
8 EBI-948630,EBI-715531 RBM4B  
  .entrainment of circadian clock by photoperiod
.circadian regulation of gene expression
.positive regulation of gene expression
  + 4 more...
.poly(A) RNA binding
.zinc ion binding
.nucleotide binding
.nucleolus
9 EBI-948630,EBI-1018153 HNRNPUL1  
  .gene expression
.response to virus
.RNA splicing
  + 4 more...
.poly(A) RNA binding
.enzyme binding
.RNA binding
.ribonucleoprotein complex
.nucleoplasm
.nucleus
10 EBI-948630,EBI-541426 AP1M1  
  .membrane organization
.regulation of defense response to virus by virus
.endosome to melanosome transport
  + 5 more...
.N/A .extracellular exosome
.trans-Golgi network membrane
.clathrin-coated endocytic vesicle membrane
  + 6 more...
11 EBI-948630,EBI-74615 TOLLIP  
  .leukocyte activation
.innate immune response
.protein localization to endosome
  + 8 more...
.Toll-like receptor binding
.kinase binding
.signal transducer activity
.extracellular exosome
.perinuclear region of cytoplasm
.interleukin-1 receptor complex
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood8
bone13
brain56
embryonic tissue93
eye33
heart11
intestine4
kidney61
liver14
lung23
lymph node89
mammary gland19
muscle56
nerve128
ovary49
pancreas56
parathyroid97
pituitary gland121
placenta10
prostate10
skin9
stomach20
testis103
thymus37
thyroid107
trachea135
uterus17
Health State
TissuesTPM*
normal52
breast (mammary gland) tumor32
colorectal tumor8
gastrointestinal tumor25
germ cell tumor45
glioma9
head and neck tumor37
kidney tumor14
liver tumor10
non-neoplasia51
ovarian tumor52
primitive neuroectodermal tumor of the CNS7
skin tumor15
soft tissue/muscle tissue tumor15
uterine tumor22
Developmental Stage
TissuesTPM*
adult34
embryoid body42
blastocyst97
fetus66
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.9
adrenal gland11.4
appendix6.7
bone marrow2.1
cerebral cortex24.1
colon4.6
duodenum3.2
esophagus4
gallbladder7.1
heart muscle9.5
kidney10.7
liver2.4
lung7.3
lymph node11.2
ovary11.7
pancreas2.4
placenta4.2
prostate9.9
salivary gland2.6
skin3.4
small intestine4.2
spleen8.3
stomach7.5
testis39.2
thyroid gland12.9
urinary bladder5.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608672, gene) Daz-interacting protein 3OMIM


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