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> Protein (NX_Q86Y26)
Protein (NX_Q86Y26)
Protein
Gene SymbolNUTM1 to neXtProt (NX_Q86Y26)
DescriptionNUT family member 1
Chromosome15
Location15q14 (34635516 ~ 34649938) to Ensembl
Sequene Features : Isoforms 4, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 65 3
2014-09-19protein level
4 129 3
2014-05-27protein level
2 127 3
2014-02-25protein level
2 126 3
2013-12-09protein level
2 94 3
2013-11-01protein level
2 90 3
2013-09-12protein level
2 90 3
2013-08-17protein level
2 90 3
2013-07-15protein level
2 63 3
2013-06-11protein level
2 63 3
2013-02-12protein level
2 36 3
2012-12-20protein level
2 36 3
2012-10-30protein level
2 45 3
2012-10-07protein level
2 45 3
2012-08-24protein level
2 44 3
2012-07-28protein level
2 44 3
2012-06-08protein level
2 6 3
2012-05-07protein level
2 6 3
2012-04-10protein level
2 6 3
2012-01-13protein level
2 6 3
2011-12-20protein level
2 7 3
2011-11-11protein level
2 7 3
2011-08-23protein level
2 7 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86Y26-1
0 43 0 120239.0525
NX_Q86Y26-2
2 12 0 46322.8291
NX_Q86Y26-3
1 42 0 122465.2522
NX_Q86Y26-4
2 43 0 123263.6689
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10178410,EBI-747061 ZMYND10  
  .motile cilium assembly
.inner dynein arm assembly
.outer dynein arm assembly
.metal ion binding .centriolar satellite
.cytoplasm
2 EBI-10178410,EBI-2880203 NEBL  
  .cardiac muscle thin filament assembly .actin filament binding
.filamin binding
.structural constituent of muscle
  + 2 more...
.extracellular exosome
.I band
.Z disc
.stress fiber
3 EBI-10178410,EBI-79934 ALOX5  
  .lipoxin metabolic process
.small molecule metabolic process
.lipoxygenase pathway
  + 4 more...
.iron ion binding
.arachidonate 5-lipoxygenase activity
.nuclear membrane
.nuclear matrix
.cytosol
  + 3 more...
4 EBI-10178410,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
5 EBI-10178410,EBI-8639312 LMO1  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.zinc ion binding .nucleus
6 EBI-10178410,EBI-1383852 PRKAA2  
  .regulation of energy homeostasis
.membrane organization
.fatty acid homeostasis
  + 31 more...
.[acetyl-CoA carboxylase] kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
.metal ion binding
  + 7 more...
.AMP-activated protein kinase complex
.cytosol
.cytoplasm
.nucleoplasm
7 EBI-10178410,EBI-10175039 TP53BP2  
  .positive regulation of execution phase of apoptosis
.intrinsic apoptotic signaling pathway by p53 class mediator
.negative regulation of cell cycle
  + 7 more...
.NF-kappaB binding
.identical protein binding
.SH3/SH2 adaptor activity
.p53 binding
.perinuclear region of cytoplasm
.cytoplasm
.nucleus
8 EBI-10178410,EBI-1236916 PSME4  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 24 more...
.lysine-acetylated histone binding
.peptidase activator activity
.spermatoproteasome complex
.nuclear speck
.cytosol
.nucleus
9 EBI-10178410,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
10 EBI-10178410,EBI-8474075 LHX8  
  .odontogenesis of dentin-containing tooth
.forebrain neuron development
.female gonad development
  + 3 more...
.sequence-specific DNA binding
.zinc ion binding
.female germ cell nucleus
11 EBI-10178410,EBI-10181968 P4HA3  
  .N/A .L-ascorbic acid binding
.oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
.iron ion binding
.procollagen-proline 4-dioxygenase activity
.endoplasmic reticulum lumen
12 EBI-10178410,EBI-10269566 MORN4  
  .N/A .N/A .N/A
13 EBI-10178410,EBI-742259 LMO3  
  .positive regulation of glucocorticoid receptor signaling pathway
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of fat cell differentiation
  + 3 more...
.zinc ion binding .cytoplasm
14 EBI-10178410,EBI-10175300 CCHCR1  
  .cell differentiation
.multicellular organismal development
.protein export from nucleus
.N/A .centriole
.cytoplasm
.nucleus
15 EBI-10178410,EBI-720457 HSPBAP1  
  .N/A .N/A .cytoplasm
16 EBI-10178410,EBI-747035 SH2D4A  
  .negative regulation of phosphatase activity .phosphatase binding .cytoplasm
17 EBI-10178410,EBI-9091816 RIC8A  
  .basement membrane organization
.cell-cell adhesion involved in gastrulation
.positive regulation of GTPase activity
  + 6 more...
.GTPase activator activity
.guanyl-nucleotide exchange factor activity
.G-protein alpha-subunit binding
.plasma membrane
.cytoplasm
18 EBI-10178410,EBI-1047497 SAMD4A  
  .positive regulation of translation
.negative regulation of translation
.poly(A) RNA binding
.translation repressor activity
.synapse
.dendrite
.cell junction
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain1
testis153
Health State
TissuesTPM*
normal4
germ cell tumor18
Developmental Stage
TissuesTPM*
adult3
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis12.8
Tissues
TissuesExpression level
adrenal glandHigh
bone marrowMedium
cerebellumMedium
colonMedium
duodenumLow
epididymisHigh
esophagusHigh
gallbladderLow
heart muscleLow
hippocampusMedium
kidneyLow
lateral ventricleMedium
liverLow
lungLow
oral mucosaHigh
pancreasLow
parathyroid glandMedium
placentaLow
prostateLow
skin 1Medium
skin 2Medium
stomach 1Medium
stomach 2Low
testisHigh
tonsilLow
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608963, gene) Nuclear protein in testisOMIM
2lethal midline carcinomaCGP


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