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> Protein (NX_Q86Y33)
Protein (NX_Q86Y33)
Protein
Gene SymbolCDC20B to neXtProt (NX_Q86Y33)
DescriptionCell division cycle protein 20 homolog B
Chromosome5
Location5q11.2 (54408799 ~ 54469005) to Ensembl
Sequene Features : Isoforms 5, Variants 88, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 88 0
2014-09-19protein level
5 68 0
2014-05-27transcript level
5 68 0
2014-02-25transcript level
5 67 0
2013-12-09transcript level
5 55 0
2013-11-01transcript level
5 52 0
2013-09-12transcript level
5 52 0
2013-08-17transcript level
5 52 0
2013-07-15transcript level
5 35 0
2013-06-11transcript level
5 35 0
2013-02-12transcript level
5 22 0
2012-12-20transcript level
5 21 0
2012-10-30transcript level
5 26 0
2012-10-07transcript level
5 26 0
2012-08-24transcript level
5 23 0
2012-07-28transcript level
5 23 0
2012-06-08transcript level
5 23 0
2012-05-07transcript level
5 23 0
2012-04-10transcript level
5 23 0
2012-01-13transcript level
5 10 0
2011-12-20transcript level
5 10 0
2011-11-11transcript level
5 10 0
2011-08-23transcript level
5 10 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86Y33-1
0 23 0 57298.7652
NX_Q86Y33-2
0 22 0 56890.5864
NX_Q86Y33-3
1 20 0 52864.6106
NX_Q86Y33-4
3 11 0 41822.8971
NX_Q86Y33-5
3 6 0 21683.6767
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10260504,EBI-741602 TRIM37  
  .aggresome assembly
.protein autoubiquitination
.positive regulation of NF-kappaB transcription factor activity
  + 7 more...
.ubiquitin protein ligase activity
.protein homodimerization activity
.ubiquitin protein ligase binding
  + 5 more...
.perinuclear region of cytoplasm
.aggresome
.cytosol
  + 2 more...
2 EBI-10260504,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
3 EBI-10260504,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
4 EBI-10260504,EBI-10178634 MAGEA11  
  .N/A .N/A .cytoplasm
.nucleoplasm
.nucleus
5 EBI-10260504,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
6 EBI-10260504,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
7 EBI-10260504,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
8 EBI-10260504,EBI-2808286 CCDC57  
  .N/A .N/A .N/A
9 EBI-10260504,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
10 EBI-10260504,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
11 EBI-10260504,EBI-413317 SPAG5  
  .regulation of attachment of spindle microtubules to kinetochore
.cell division
.chromosome segregation
  + 2 more...
.N/A .mitotic spindle
.microtubule plus-end
.midbody
  + 7 more...
12 EBI-10260504,EBI-721354 PLK2  
  .negative regulation of dendritic spine development
.long term synaptic depression
.long-term synaptic potentiation
  + 13 more...
.ATP binding
.signal transducer activity
.protein serine/threonine kinase activity
.dendrite
.centriole
.centrosome
.intracellular
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain1
kidney9
liver9
lung5
mammary gland6
mouth30
trachea19
uterus17
Health State
TissuesTPM*
normal1
breast (mammary gland) tumor10
germ cell tumor15
head and neck tumor14
primitive neuroectodermal tumor of the CNS15
uterine tumor44
Developmental Stage
TissuesTPM*
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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