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> Protein (NX_Q86Y82)
Protein (NX_Q86Y82)
Protein
Gene SymbolSTX12 to neXtProt (NX_Q86Y82)
DescriptionSyntaxin-12
Chromosome1
Location1p35.3 (28099694 ~ 28150963) to Ensembl
Sequene Features : Isoforms 1, Variants 24, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein stabilization
.vesicle docking
.cholesterol efflux
  + 2 more...
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.phagocytic vesicle
.membrane raft
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 24 7
2014-09-19protein level
1 21 7
2014-05-27protein level
1 21 7
2014-02-25protein level
1 21 7
2013-12-09protein level
1 16 7
2013-11-01protein level
1 16 5
2013-09-12protein level
1 16 3
2013-08-17protein level
1 16 3
2013-07-15protein level
1 6 3
2013-06-11protein level
1 6 3
2013-02-12protein level
1 2 3
2012-12-20protein level
1 2 3
2012-10-30protein level
1 5 3
2012-10-07protein level
1 5 3
2012-08-24protein level
1 5 3
2012-07-28protein level
1 5 3
2012-06-08protein level
1 6 3
2012-05-07protein level
1 4 3
2012-04-10protein level
1 4 3
2012-01-13protein level
1 3 3
2011-12-20protein level
1 3 3
2011-11-11protein level
1 3 3
2011-08-23protein level
1 3 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86Y82-1
12 0 0 31622.1898
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2691717,EBI-784112 ABCA1  
  .anion transmembrane transport
.cellular response to cholesterol
.cellular response to retinoic acid
  + 32 more...
.ATPase binding
.ATPase activity, coupled to transmembrane movement of substances
.apolipoprotein A-I receptor activity
  + 11 more...
.perinuclear region of cytoplasm
.phagocytic vesicle
.membrane raft
  + 6 more...
2 EBI-2691717,EBI-490676 SNAP29  
  .membrane fusion
.synaptic vesicle fusion to presynaptic membrane
.synaptic vesicle priming
  + 4 more...
.syntaxin binding
.SNAP receptor activity
.synapse
.neuron projection
.SNARE complex
  + 4 more...
3 EBI-2691717,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland121
bladder100
blood49
bone69
bone marrow205
brain83
connective tissue26
embryonic tissue56
eye71
heart11
intestine43
kidney94
larynx127
liver53
lung71
lymph45
lymph node44
mammary gland66
mouth45
muscle56
ovary29
pancreas74
parathyroid194
pituitary gland121
placenta91
prostate36
skin52
spleen18
stomach52
testis57
thymus12
thyroid128
trachea19
uterus81
vascular38
Health State
TissuesTPM*
normal72
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor32
chondrosarcoma72
colorectal tumor35
gastrointestinal tumor50
germ cell tumor68
glioma93
head and neck tumor67
kidney tumor29
leukemia31
liver tumor83
lung tumor29
lymphoma83
non-neoplasia82
ovarian tumor39
pancreatic tumor66
primitive neuroectodermal tumor of the CNS23
prostate cancer28
retinoblastoma64
skin tumor31
soft tissue/muscle tissue tumor31
uterine tumor55
Developmental Stage
TissuesTPM*
adult86
embryoid body28
blastocyst48
fetus62
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue54.7
adrenal gland31.4
appendix34.4
bone marrow9.2
cerebral cortex49.9
colon32.9
duodenum35.1
esophagus43.9
gallbladder47.2
heart muscle15.6
kidney29.1
liver15.5
lung47.1
lymph node28.4
ovary21.8
pancreas14.3
placenta28.2
prostate29.9
salivary gland21.8
skin26.5
small intestine32.1
spleen29.8
stomach48.2
testis15.6
thyroid gland98.8
urinary bladder36.5
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusLow
fallopian tubeMedium
gallbladderHigh
hippocampusMedium
kidneyHigh
lateral ventricleHigh
liverMedium
lungHigh
lymph nodeLow
nasopharynxLow
oral mucosaMedium
ovaryLow
pancreasHigh
parathyroid glandLow
placentaMedium
prostateMedium
rectumHigh
salivary glandLow
seminal vesicleHigh
skin 1Medium
skin 2Low
small intestineHigh
smooth muscleLow
soft tissue 1Low
soft tissue 2Low
stomach 1High
stomach 2High
testisHigh
thyroid glandMedium
tonsilLow
urinary bladderHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606892, gene) Syntaxin 12; STX12OMIM


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