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> Protein (NX_Q86YD7)
Protein (NX_Q86YD7)
Protein
Gene SymbolFAM90A1 to neXtProt (NX_Q86YD7)
DescriptionProtein FAM90A1
Chromosome12
Location12p13.31 (8373856 ~ 8380214) to Ensembl
Sequene Features : Isoforms 1, Variants 109, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .zinc ion binding
.nucleic acid binding
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 109 0
2014-09-19transcript level
1 79 0
2014-05-27transcript level
1 79 0
2014-02-25transcript level
1 77 0
2013-12-09transcript level
1 58 0
2013-11-01transcript level
1 58 0
2013-09-12transcript level
1 58 0
2013-08-17transcript level
1 58 0
2013-07-15transcript level
1 45 0
2013-06-11transcript level
1 45 0
2013-02-12transcript level
1 31 0
2012-12-20transcript level
1 31 0
2012-10-30transcript level
1 32 0
2012-10-07transcript level
1 32 0
2012-08-24transcript level
1 29 0
2012-07-28transcript level
1 29 0
2012-06-08transcript level
1 31 0
2012-05-07transcript level
1 30 0
2012-04-10transcript level
1 30 0
2012-01-13transcript level
1 27 0
2011-12-20transcript level
1 27 0
2011-11-11transcript level
1 27 0
2011-08-23transcript level
1 27 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86YD7-1
25 0 0 49762.3752
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6658203,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-6658203,EBI-1050964 PSTPIP1  
  .innate immune response
.nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
.signal transduction
  + 3 more...
.N/A .perinuclear region of cytoplasm
.cleavage furrow
.lamellipodium
  + 5 more...
3 EBI-6658203,EBI-10176632 ZBTB14  
  .negative regulation of transcription, DNA-templated
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 2 more...
.cytoplasm
.nucleoplasm
.nucleus
4 EBI-6658203,EBI-714135 STX11  
  .membrane fusion
.vesicle docking
.natural killer cell degranulation
  + 4 more...
.SNAP receptor activity
.SNARE binding
.SNARE complex
.integral component of membrane
.endomembrane system
  + 3 more...
5 EBI-6658203,EBI-1047263 KRT38  
  .N/A .structural molecule activity .extracellular exosome
.intermediate filament
6 EBI-6658203,EBI-740738 LDOC1  
  .negative regulation of cell proliferation .N/A .nucleolus
.nucleus
7 EBI-6658203,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
8 EBI-6658203,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
9 EBI-6658203,EBI-618165 GABPB1  
  .positive regulation of transcription from RNA polymerase II promoter
.mitochondrion organization
.organelle organization
  + 2 more...
.protein heterodimerization activity
.transcription regulatory region DNA binding
.sequence-specific DNA binding transcription factor activity
.nucleoplasm
.nucleus
10 EBI-6658203,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
11 EBI-6658203,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
12 EBI-6658203,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
13 EBI-6658203,EBI-741101 FHL3  
  .actin cytoskeleton organization
.muscle organ development
.zinc ion binding .Z disc
.focal adhesion
.nucleus
.stress fiber
14 EBI-6658203,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
15 EBI-6658203,EBI-2808286 CCDC57  
  .N/A .N/A .N/A
16 EBI-6658203,EBI-1104907 GNPTAB  
  .carbohydrate phosphorylation
.cell differentiation
.N-glycan processing to lysosome
  + 2 more...
.calcium ion binding
.UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
.integral component of membrane
.Golgi apparatus
.nucleus
.Golgi membrane
17 EBI-6658203,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
18 EBI-6658203,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
19 EBI-6658203,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
20 EBI-6658203,EBI-747107 SIAH1  
  .positive regulation of intrinsic apoptotic signaling pathway
.neuron apoptotic process
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 11 more...
.ubiquitin protein ligase activity
.identical protein binding
.ligase activity
  + 3 more...
.beta-catenin destruction complex
.plasma membrane
.cytosol
  + 3 more...
21 EBI-6658203,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
22 EBI-6658203,EBI-744695 BANP  
  .negative regulation of protein catabolic process
.protein localization to nucleus
.chromatin modification
  + 4 more...
.DNA binding .nucleoplasm
23 EBI-6658203,EBI-742887 CEP76  
  .regulation of centriole replication
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .protein complex
.cytosol
.centriole
.centrosome
24 EBI-6658203,EBI-371922 EXOSC8  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
.rRNA processing
.nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
.AU-rich element binding .cytosol
.cytoplasm
.nucleolus
  + 2 more...
25 EBI-6658203,EBI-745680 STAC3  
  .skeletal muscle fiber development
.intracellular signal transduction
.neuromuscular synaptic transmission
.skeletal muscle contraction
.metal ion binding
.identical protein binding
.N/A
26 EBI-6658203,EBI-349832 GOPC  
  .protein homooligomerization
.regulation of catalytic activity
.apical protein localization
  + 6 more...
.ion channel binding .postsynaptic membrane
.protein complex
.Golgi-associated vesicle membrane
  + 9 more...
27 EBI-6658203,EBI-739498 CEP72  
  .gamma-tubulin complex localization
.spindle organization
.organelle organization
  + 2 more...
.N/A .cytosol
.centrosome
28 EBI-6658203,EBI-1640204 ZNF212  
  .regulation of transcription from RNA polymerase II promoter
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.identical protein binding
.zinc ion binding
.transcription cofactor activity
.DNA binding
.nucleus
29 EBI-6658203,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain1
lung5
pancreas4
testis11
Health State
TissuesTPM*
normal1
germ cell tumor26
Developmental Stage
TissuesTPM*
adult2
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*613041, gene) Family with sequence similarity 90, member a1; FAM90A1OMIM


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