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> Protein (NX_Q86YR7)
Protein (NX_Q86YR7)
Protein
Gene SymbolMCF2L2 to neXtProt (NX_Q86YR7)
DescriptionProbable guanine nucleotide exchange factor MCF2L2
Chromosome3
Location3q27.1 (182895831 ~ 183146566) to Ensembl
Sequene Features : Isoforms 4, Variants 180, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .Rho guanyl-nucleotide exchange factor activity .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
4 180 0
2014-09-19transcript level
4 138 0
2014-05-27transcript level
4 138 0
2014-02-25transcript level
4 137 0
2013-12-09transcript level
4 116 0
2013-11-01transcript level
4 111 0
2013-09-12transcript level
4 111 0
2013-08-17transcript level
4 111 0
2013-07-15transcript level
4 73 0
2013-06-11transcript level
4 73 0
2013-02-12transcript level
4 43 0
2012-12-20transcript level
4 42 0
2012-10-30transcript level
4 46 0
2012-10-07transcript level
4 46 0
2012-08-24transcript level
4 33 0
2012-07-28transcript level
4 33 0
2012-06-08transcript level
4 34 0
2012-05-07transcript level
4 34 0
2012-04-10transcript level
4 34 0
2012-01-13transcript level
4 24 0
2011-12-20transcript level
4 24 0
2011-11-11transcript level
4 24 0
2011-08-23transcript level
4 24 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86YR7-1
2 54 0 126912.3125
NX_Q86YR7-2
0 37 0 81825.1338
NX_Q86YR7-3
0 31 0 71866.8646
NX_Q86YR7-4
0 54 0 122844.265
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bone27
brain19
connective tissue13
embryonic tissue18
intestine17
kidney9
larynx85
liver14
lung14
lymph node22
mammary gland13
mouth105
muscle28
pancreas23
pharynx24
placenta21
prostate10
salivary gland49
skin4
stomach52
testis11
thyroid21
trachea19
uterus17
vascular19
Health State
TissuesTPM*
normal19
breast (mammary gland) tumor21
colorectal tumor26
gastrointestinal tumor16
germ cell tumor7
glioma18
head and neck tumor82
kidney tumor14
liver tumor10
lymphoma13
non-neoplasia10
primitive neuroectodermal tumor of the CNS15
prostate cancer19
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult27
fetus16
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland9.6
appendix1.2
cerebral cortex11.3
colon1.2
duodenum1.1
esophagus1.2
prostate1.1
spleen3.2
testis5.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#125853, phenotype) Diabetes mellitus, noninsulin-dependent; NIDDMOMIM


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