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> Protein (NX_Q8IUC2)
Protein (NX_Q8IUC2)
Protein
Gene SymbolKRTAP8-1 to neXtProt (NX_Q8IUC2)
DescriptionKeratin-associated protein 8-1
Chromosome21
Location21q22.11 (32185016 ~ 32185570) to Ensembl
Sequene Features : Isoforms 1, Variants 20, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .intermediate filament
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 20 0
2014-09-19transcript level
1 16 0
2014-05-27transcript level
1 16 0
2014-02-25transcript level
1 16 0
2013-12-09transcript level
1 15 0
2013-11-01transcript level
1 15 0
2013-09-12transcript level
1 15 0
2013-08-17transcript level
1 15 0
2013-07-15transcript level
1 8 0
2013-06-11transcript level
1 8 0
2013-02-12transcript level
1 2 0
2012-12-20transcript level
1 2 0
2012-10-30transcript level
1 2 0
2012-10-07transcript level
1 2 0
2012-08-24transcript level
1 1 0
2012-07-28transcript level
1 1 0
2012-06-08transcript level
1 1 0
2012-05-07transcript level
1 1 0
2012-04-10transcript level
1 1 0
2012-01-13transcript level
1 2 0
2011-12-20transcript level
1 2 0
2011-11-11transcript level
1 2 0
2011-08-23transcript level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8IUC2-1
1 0 0 6820.9295
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10261141,EBI-7875264 DAB1  
  .lateral motor column neuron migration
.Golgi localization
.negative regulation of axonogenesis
  + 15 more...
.N/A .perinuclear region of cytoplasm
.apical part of cell
.neuronal cell body
  + 5 more...
2 EBI-10261141,EBI-348380 PSMA3  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.proteasome core complex
  + 5 more...
3 EBI-10261141,EBI-724310 DAZAP2  
  .N/A .WW domain binding .cytoplasm
.nucleus
4 EBI-10261141,EBI-740322 RBPMS  
  .positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
Expression level of Protein (ref. Human Protein Atlas)
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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