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> Protein (NX_Q8IUH3)
Protein (NX_Q8IUH3)
Protein
Gene SymbolRBM45 to neXtProt (NX_Q8IUH3)
DescriptionRNA-binding protein 45
Chromosome2
Location2q31.2 (178977151 ~ 179003738) to Ensembl
Sequene Features : Isoforms 3, Variants 46, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell differentiation
.nervous system development
.poly(A) RNA binding
.RNA binding
.nucleotide binding
.cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 46 0
2014-09-19protein level
3 38 0
2014-05-27protein level
3 38 0
2014-02-25protein level
3 37 0
2013-12-09protein level
3 30 0
2013-11-01protein level
3 30 0
2013-09-12protein level
3 30 0
2013-08-17protein level
3 30 0
2013-07-15protein level
3 20 0
2013-06-11protein level
3 20 0
2013-02-12protein level
3 7 8
2012-12-20protein level
3 7 8
2012-10-30protein level
3 9 8
2012-10-07protein level
3 9 4
2012-08-24protein level
3 9 4
2012-07-28protein level
3 9 4
2012-06-08protein level
3 0 4
2012-05-07protein level
3 0 4
2012-04-10protein level
3 0 4
2012-01-13protein level
3 0 4
2011-12-20protein level
3 2 4
2011-11-11protein level
3 2 4
2011-08-23protein level
3 2 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8IUH3-1
1 20 0 53468.6382
NX_Q8IUH3-2
1 14 0 37049.1038
NX_Q8IUH3-3
0 21 0 53312.5488
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2512147,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
2 EBI-2512147,EBI-2932492 TXN2  
  .oxidation-reduction process
.response to axon injury
.cell redox homeostasis
  + 12 more...
.peptide-methionine (R)-S-oxide reductase activity
.oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
.protein disulfide oxidoreductase activity
.peptide-methionine (S)-S-oxide reductase activity
.neuronal cell body
.dendrite
.mitochondrial matrix
  + 2 more...
3 EBI-2512147,EBI-2339898 FANCL  
  .regulation of cell proliferation
.gamete generation
.cellular response to DNA damage stimulus
  + 3 more...
.ubiquitin protein ligase activity
.ubiquitin protein ligase binding
.ligase activity
  + 2 more...
.Fanconi anaemia nuclear complex
.cytoplasm
.nucleoplasm
.nuclear envelope
4 EBI-2512147,EBI-1104564 MEMO1  
  .regulation of microtubule-based process .N/A .cytosol
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood16
brain13
embryonic tissue18
esophagus49
eye19
heart33
intestine4
liver19
lung20
lymph node22
mammary gland19
ovary9
pancreas4
placenta14
skin9
testis6
Health State
TissuesTPM*
normal14
breast (mammary gland) tumor10
colorectal tumor8
esophageal tumor57
germ cell tumor18
glioma37
leukemia21
liver tumor10
lymphoma55
non-neoplasia10
retinoblastoma21
Developmental Stage
TissuesTPM*
adult10
embryoid body14
blastocyst16
fetus16
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5
adrenal gland6.4
appendix8.7
bone marrow4.6
cerebral cortex5.3
colon7.8
duodenum7.3
esophagus5.6
gallbladder6.3
heart muscle5
kidney5.8
liver3.4
lung7.1
lymph node10.7
ovary5.9
pancreas2.8
placenta3.9
prostate8.4
salivary gland5.7
skin6.6
small intestine7.6
spleen7.1
stomach6.9
testis8.1
thyroid gland8.8
urinary bladder7.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608888, gene) Developmentally regulated rna-binding protein 1OMIM


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