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> Protein (NX_Q8IVL1)
Protein (NX_Q8IVL1)
Protein
Gene SymbolNAV2 to neXtProt (NX_Q8IVL1)
DescriptionNeuron navigator 2
Chromosome11
Location11p15.1 (19372271 ~ 20143144) to Ensembl
Sequene Features : Isoforms 13, Variants 340, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.vagus nerve development
.glossopharyngeal nerve development
.optic nerve development
  + 4 more...
.heparin binding
.ATP binding
.helicase activity
.nucleoplasm
.interstitial matrix
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
13 340 6
2014-09-19protein level
13 278 6
2014-05-27protein level
13 277 6
2014-02-25protein level
13 276 6
2013-12-09protein level
13 218 6
2013-11-01protein level
13 208 6
2013-09-12protein level
13 208 6
2013-08-17protein level
13 208 6
2013-07-15protein level
13 150 6
2013-06-11protein level
13 150 6
2013-02-12protein level
13 81 55
2012-12-20protein level
13 79 55
2012-10-30protein level
13 88 55
2012-10-07protein level
13 88 5
2012-08-24protein level
13 85 5
2012-07-28protein level
13 85 5
2012-06-08protein level
13 18 5
2012-05-07protein level
13 18 5
2012-04-10protein level
13 18 5
2012-01-13protein level
13 18 5
2011-12-20protein level
13 19 5
2011-11-11protein level
13 19 5
2011-08-23protein level
13 19 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8IVL1-1
0 107 5 268001.7634
NX_Q8IVL1-10
2 101 5 260947.8457
NX_Q8IVL1-11
0 104 5 261704.2987
NX_Q8IVL1-12
1 101 5 261416.9957
NX_Q8IVL1-13
1 102 5 260940.84
NX_Q8IVL1-2
0 104 5 261588.4721
NX_Q8IVL1-3
0 104 5 261246.3191
NX_Q8IVL1-4
0 100 6 254820.7962
NX_Q8IVL1-5
2 62 3 161846.298
NX_Q8IVL1-6
1 36 3 97622.5613
NX_Q8IVL1-7
1 24 2 66854.3738
NX_Q8IVL1-8
1 101 5 259810.354
NX_Q8IVL1-9
1 102 5 260047.3768
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741200,EBI-348555 PIAS2  
  .negative regulation of androgen receptor signaling pathway
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 7 more...
.SUMO ligase activity
.androgen receptor binding
.ligase activity
  + 4 more...
.nuclear speck
.PML body
.nucleoplasm
.nucleus
2 EBI-741200,EBI-10245749 CCDC147  
  .N/A .N/A .cilium
.extracellular space
3 EBI-741200,EBI-2809203 ADAT2  
  .tRNA wobble adenosine to inosine editing .zinc ion binding
.tRNA-specific adenosine deaminase activity
.N/A
4 EBI-741200,EBI-726721 RBM15B  
  .viral process
.RNA splicing
.mRNA processing
  + 3 more...
.poly(A) RNA binding
.RNA binding
.nucleotide binding
.nucleoplasm
5 EBI-741200,EBI-488533 ING5  
  .positive regulation of apoptotic signaling pathway
.negative regulation of growth
.positive regulation of transcription, DNA-templated
  + 7 more...
.methylated histone binding
.zinc ion binding
.chromatin binding
.MOZ/MORF histone acetyltransferase complex
.nucleoplasm
.nucleus
6 EBI-741200,EBI-2514922 RBM15  
  .placenta blood vessel development
.ventricular septum morphogenesis
.spleen development
  + 4 more...
.poly(A) RNA binding
.nucleotide binding
.nuclear membrane
.nucleoplasm
7 EBI-741200,EBI-399246 MORF4L1  
  .histone H2A acetylation
.histone H4 acetylation
.regulation of growth
  + 6 more...
.protein N-terminus binding
.chromatin binding
.NuA4 histone acetyltransferase complex
.Sin3 complex
.nucleoplasm
8 EBI-741200,EBI-2866661 ING4  
  .negative regulation of growth
.negative regulation of transcription, DNA-templated
.histone H4-K12 acetylation
  + 11 more...
.methylated histone binding
.zinc ion binding
.transcription coactivator activity
.nucleoplasm
.nucleus
.histone acetyltransferase complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
bone41
bone marrow20
brain50
connective tissue20
embryonic tissue98
eye28
heart55
intestine25
kidney47
larynx42
liver29
lung89
mammary gland46
mouth15
muscle56
nerve64
ovary29
pancreas60
pharynx24
placenta49
skin80
stomach10
testis20
thymus12
thyroid193
trachea19
uterus77
vascular19
Health State
TissuesTPM*
normal11
breast (mammary gland) tumor32
chondrosarcoma48
colorectal tumor35
gastrointestinal tumor8
germ cell tumor83
glioma37
kidney tumor14
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult52
embryoid body228
blastocyst48
fetus73
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.8
adrenal gland2.3
appendix4.1
bone marrow1.9
cerebral cortex11.2
colon5.2
duodenum4.6
esophagus8.1
gallbladder2.8
heart muscle5
kidney12.9
liver9.5
lung12.7
lymph node2.3
ovary3.7
pancreas4.6
placenta16.7
prostate4.4
salivary gland14.3
skin2
small intestine3.6
spleen1.6
stomach3.8
testis1.2
thyroid gland19.4
urinary bladder3.5
Tissues
TissuesExpression level
adrenal glandLow
appendixHigh
bone marrowMedium
breastHigh
bronchusMedium
cerebellumMedium
cerebral cortexLow
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
kidneyHigh
liverLow
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandHigh
placentaHigh
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleHigh
skeletal muscleMedium
skin 1Low
skin 2Medium
small intestineHigh
smooth muscleLow
spleenMedium
stomach 1High
stomach 2High
testisMedium
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607026, gene) Neuron navigator 2; NAV2OMIM


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