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> Protein (NX_Q8IWL2)
Protein (NX_Q8IWL2)
Protein
Gene SymbolSFTPA1 to neXtProt (NX_Q8IWL2)
DescriptionPulmonary surfactant-associated protein A1
Chromosome10
Location10q22.3 (81370695 ~ 81375196) to Ensembl
Sequene Features : Isoforms 2, Variants 42, PTMs 14 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.respiratory gaseous exchange
.lipid transport
.carbohydrate binding
.lipid transporter activity
.extracellular space
.collagen trimer
.proteinaceous extracellular matrix
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 42 14
2014-09-19protein level
2 34 14
2014-05-27protein level
2 34 14
2014-02-25protein level
2 34 14
2013-12-09protein level
2 29 14
2013-11-01protein level
2 28 14
2013-09-12protein level
2 28 14
2013-08-17protein level
2 28 14
2013-07-15protein level
1 23 14
2013-06-11protein level
1 23 14
2013-02-12protein level
1 20 14
2012-12-20protein level
1 21 14
2012-10-30protein level
1 22 14
2012-10-07protein level
1 22 14
2012-08-24protein level
1 20 14
2012-07-28protein level
1 20 14
2012-06-08protein level
1 23 14
2012-05-07protein level
1 22 14
2012-04-10protein level
1 22 14
2012-01-13protein level
1 16 14
2011-12-20protein level
1 16 14
2011-11-11protein level
1 16 14
2011-08-23protein level
1 16 14
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8IWL2-1
1 1 8 26225.5073
NX_Q8IWL2-2
2 1 8 27718.242
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
connective tissue6
kidney4
lung588
lymph node11
pancreas4
prostate21
Health State
TissuesTPM*
normal62
chondrosarcoma12
leukemia10
lung tumor136
non-neoplasia238
Developmental Stage
TissuesTPM*
adult118
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland3.5
appendix2.1
lung5366
placenta1.3
prostate3.6
spleen4.1
stomach3.9
Tissues
TissuesExpression level
gallbladderLow
kidneyLow
lungHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#178500, phenotype) Pulmonary fibrosis, idiopathic; IPFOMIM
2(*178630, gene) Surfactant, pulmonary-associated protein a1; SFTPA1OMIM
3(#267450, phenotype) Respiratory distress syndrome in premature infantsOMIM


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