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> Protein (NX_Q8IWL3)
Protein (NX_Q8IWL3)
Protein
Gene SymbolHSCB to neXtProt (NX_Q8IWL3)
DescriptionIron-sulfur cluster co-chaperone protein HscB, mitochondrial
Chromosome22
Location22q12.1 (29138019 ~ 29153503) to Ensembl
Sequene Features : Isoforms 1, Variants 22, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein oligomerization
.iron-sulfur cluster assembly
.protein folding
.metal ion binding .plasma membrane
.centrosome
.mitochondrion
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 22 0
2014-09-19protein level
1 17 0
2014-05-27protein level
1 17 0
2014-02-25protein level
1 17 0
2013-12-09protein level
1 16 0
2013-11-01protein level
1 16 0
2013-09-12protein level
1 16 0
2013-08-17protein level
1 16 0
2013-07-15protein level
1 9 0
2013-06-11protein level
1 9 0
2013-02-12protein level
1 5 0
2012-12-20protein level
1 5 0
2012-10-30protein level
1 5 0
2012-10-07protein level
1 5 0
2012-08-24protein level
1 5 0
2012-07-28protein level
1 5 0
2012-06-08protein level
1 11 0
2012-05-07protein level
1 11 0
2012-04-10protein level
1 11 0
2012-01-13protein level
1 11 0
2011-12-20protein level
1 11 0
2011-11-11protein level
1 11 0
2011-08-23protein level
1 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8IWL3-1
13 0 0 27404.644
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1805738,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood8
bone13
brain3
connective tissue6
embryonic tissue4
eye9
heart22
intestine12
kidney33
liver4
lung26
lymph45
pancreas4
placenta7
prostate10
skin14
testis2
thyroid64
uterus4
Health State
TissuesTPM*
normal8
chondrosarcoma12
gastrointestinal tumor8
germ cell tumor7
lung tumor38
lymphoma27
pancreatic tumor9
retinoblastoma43
skin tumor7
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult8
embryoid body14
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.1
adrenal gland14.7
appendix12.9
bone marrow3.6
cerebral cortex7.1
colon12.4
duodenum9.5
esophagus9.2
gallbladder11.2
heart muscle6.7
kidney15.3
liver12.3
lung8
lymph node15.4
ovary15.9
pancreas6.3
placenta7
prostate14
salivary gland19.3
skin6.6
small intestine8.9
spleen10.4
stomach10.8
testis7.6
thyroid gland12.5
urinary bladder17
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowLow
breastHigh
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusLow
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusLow
kidneyHigh
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxHigh
oral mucosaLow
ovaryHigh
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumHigh
salivary glandLow
seminal vesicleLow
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1High
stomach 2High
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608142, gene) Hsc20, e. coli, homolog ofOMIM


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