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> Protein (NX_Q8IX12)
Protein (NX_Q8IX12)
Protein
Gene SymbolCCAR1 to neXtProt (NX_Q8IX12)
DescriptionCell division cycle and apoptosis regulator protein 1
Chromosome10
Location10q21.3 (70480769 ~ 70552134) to Ensembl
Sequene Features : Isoforms 2, Variants 100, PTMs 12 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.gene expression
.RNA splicing
.cell cycle
  + 4 more...
.poly(A) RNA binding
.ligand-dependent nuclear receptor transcription coactivator activity
.perinuclear region of cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 100 12
2014-09-19protein level
2 79 12
2014-05-27protein level
2 79 12
2014-02-25protein level
2 79 12
2013-12-09protein level
2 70 12
2013-11-01protein level
2 69 9
2013-09-12protein level
2 69 9
2013-08-17protein level
2 69 9
2013-07-15protein level
2 46 8
2013-06-11protein level
2 46 8
2013-02-12protein level
2 22 22
2012-12-20protein level
2 24 22
2012-10-30protein level
2 26 22
2012-10-07protein level
2 26 11
2012-08-24protein level
2 23 11
2012-07-28protein level
2 22 11
2012-06-08protein level
2 36 11
2012-05-07protein level
2 22 11
2012-04-10protein level
2 22 11
2012-01-13protein level
2 27 11
2011-12-20protein level
2 27 11
2011-11-11protein level
2 27 8
2011-08-23protein level
2 27 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8IX12-1
1 39 0 132738.6981
NX_Q8IX12-2
1 39 0 130961.8599
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-356265,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
2 EBI-356265,EBI-5661333 TRIM63  
  .cellular response to dexamethasone stimulus
.response to interleukin-1
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 5 more...
.titin binding
.ligase activity
.zinc ion binding
  + 2 more...
.M band
.Z disc
.microtubule
  + 2 more...
3 EBI-356265,EBI-747743 WWTR1  
  .negative regulation of canonical Wnt signaling pathway
.regulation of metanephric nephron tubule epithelial cell differentiation
.kidney morphogenesis
  + 23 more...
.transcription corepressor activity
.transcription coactivator activity
.cytosol
.cytoplasm
.transcription factor complex
  + 2 more...
4 EBI-356265,EBI-10239299 PIH1D3  
  .axonemal dynein complex assembly
.sperm motility
.chaperone binding .cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites150
bladder133
blood163
bone69
bone marrow123
brain129
cervix103
connective tissue80
ear124
embryonic tissue93
esophagus248
eye52
heart100
intestine94
kidney71
larynx85
liver68
lung68
lymph22
lymph node89
mammary gland79
mouth302
muscle56
ovary29
pancreas65
pharynx49
placenta24
prostate100
skin52
spleen243
stomach114
testis82
thymus225
thyroid171
trachea289
umbilical cord72
uterus94
vascular116
Health State
TissuesTPM*
normal88
adrenal tumor79
breast (mammary gland) tumor75
cervical tumor144
chondrosarcoma48
colorectal tumor71
esophageal tumor289
gastrointestinal tumor118
germ cell tumor178
glioma18
head and neck tumor216
kidney tumor58
leukemia105
liver tumor114
lung tumor68
lymphoma13
non-neoplasia82
ovarian tumor26
pancreatic tumor95
primitive neuroectodermal tumor of the CNS141
prostate cancer125
retinoblastoma86
skin tumor55
soft tissue/muscle tissue tumor31
uterine tumor77
Developmental Stage
TissuesTPM*
adult82
embryoid body128
blastocyst16
neonate128
fetus109
infant212
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.8
adrenal gland33.8
appendix36.6
bone marrow28.9
cerebral cortex19.6
colon26.7
duodenum26.3
esophagus22.9
gallbladder27.3
heart muscle12.9
kidney22.6
liver16
lung23.6
lymph node47.3
ovary27.5
pancreas12.3
placenta28.4
prostate30.4
salivary gland16.8
skin37.9
small intestine24.9
spleen33.2
stomach27.3
testis27.1
thyroid gland29.9
urinary bladder32
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastHigh
bronchusHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverHigh
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaHigh
ovaryHigh
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleHigh
skin 1High
skin 2High
small intestineHigh
smooth muscleHigh
soft tissue 1High
soft tissue 2High
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612569, gene) Cell division cycle and apoptosis regulator 1; CCAR1OMIM


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