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> Protein (NX_Q8IY31)
Protein (NX_Q8IY31)
Protein
Gene SymbolIFT20 to neXtProt (NX_Q8IY31)
DescriptionIntraflagellar transport protein 20 homolog
Chromosome17
Location17q11.2 (26655352 ~ 26662515) to Ensembl
Sequene Features : Isoforms 4, Variants 18, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of autophagic vacuole assembly
.regulation of cilium assembly
.protein localization to cilium
  + 13 more...
.N/A .ciliary base
.ciliary tip
.primary cilium
  + 13 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 18 0
2014-09-19protein level
4 15 0
2014-05-27protein level
4 14 0
2014-02-25protein level
4 14 0
2013-12-09protein level
4 11 0
2013-11-01protein level
4 11 0
2013-09-12protein level
4 11 0
2013-08-17protein level
4 11 0
2013-07-15protein level
4 8 0
2013-06-11protein level
4 8 0
2013-02-12protein level
3 6 0
2012-12-20protein level
3 6 0
2012-10-30protein level
3 4 0
2012-10-07protein level
3 4 0
2012-08-24protein level
3 4 0
2012-07-28protein level
3 4 0
2012-06-08protein level
3 0 0
2012-05-07protein level
3 0 0
2012-04-10protein level
3 0 0
2012-01-13protein level
3 0 0
2011-12-20protein level
3 3 0
2011-11-11protein level
3 3 0
2011-08-23protein level
3 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8IY31-1
0 6 0 15270.9728
NX_Q8IY31-2
2 6 0 18108.3303
NX_Q8IY31-3
5 3 0 15954.0136
NX_Q8IY31-4
0 4 0 12960.9735
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744203,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-744203,EBI-715849 NDC80  
  .attachment of mitotic spindle microtubules to kinetochore
.cell division
.attachment of spindle microtubules to kinetochore
  + 7 more...
.identical protein binding
.structural constituent of cytoskeleton
.Ndc80 complex
.membrane
.cytosol
  + 5 more...
3 EBI-744203,EBI-359352 PSMA1  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.RNA binding
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.polysome
  + 7 more...
4 EBI-744203,EBI-347978 NUP62  
  .regulation of cellular response to heat
.transmembrane transport
.mRNA transport
  + 34 more...
.thyroid hormone receptor binding
.ubiquitin binding
.SH2 domain binding
  + 3 more...
.Flemming body
.pore complex
.intracellular membrane-bounded organelle
  + 7 more...
5 EBI-744203,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
6 EBI-744203,EBI-741048 NUP54  
  .regulation of cellular response to heat
.transmembrane transport
.mRNA transport
  + 17 more...
.nucleocytoplasmic transporter activity .nuclear membrane
.cytoplasm
.nucleoplasm
  + 2 more...
7 EBI-744203,EBI-2872397 CROCCP2  
  .centrosome organization .N/A .ciliary rootlet
8 EBI-9091197,EBI-524753 ZDHHC17  
  .positive regulation of I-kappaB kinase/NF-kappaB signaling
.lipoprotein transport
.protein palmitoylation
  + 2 more...
.identical protein binding
.protein-cysteine S-palmitoyltransferase activity
.palmitoyltransferase activity
  + 3 more...
.intracellular membrane-bounded organelle
.Golgi-associated vesicle membrane
.integral component of membrane
  + 3 more...
9 EBI-744203,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
10 EBI-744203,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
11 EBI-744203,EBI-465804 DTNBP1  
  .membrane organization
.regulation of dopamine receptor signaling pathway
.platelet dense granule organization
  + 11 more...
.N/A .postsynaptic membrane
.dendritic spine
.neuron projection
  + 14 more...
12 EBI-744203,EBI-739657 KXD1  
  .vesicle-mediated transport .N/A .BLOC-1 complex
13 EBI-744203,EBI-394607 MED4  
  .positive regulation of transcription, DNA-templated
.androgen receptor signaling pathway
.intracellular steroid hormone receptor signaling pathway
  + 3 more...
.thyroid hormone receptor binding
.vitamin D receptor binding
.ligand-dependent nuclear receptor transcription coactivator activity
  + 3 more...
.mediator complex
.membrane
.nucleoplasm
.nucleus
14 EBI-744203,EBI-743598 ABI2  
  .positive regulation of Arp2/3 complex-mediated actin nucleation
.peptidyl-tyrosine phosphorylation
.Rac protein signal transduction
  + 5 more...
.proline-rich region binding
.protein complex binding
.ubiquitin protein ligase binding
  + 4 more...
.SCAR complex
.filopodium
.lamellipodium
  + 3 more...
15 EBI-744203,EBI-720048 EXOC7  
  .membrane organization
.cellular protein metabolic process
.protein transport
  + 2 more...
.N/A .centriolar satellite
.growth cone membrane
.membrane
  + 4 more...
16 EBI-744203,EBI-712969 CCDC53  
  .protein transport .N/A .WASH complex
.intracellular membrane-bounded organelle
.actin cytoskeleton
.early endosome
17 EBI-744203,EBI-744586 EMILIN1  
  .extracellular matrix organization
.positive regulation of cell-substrate adhesion
.cell adhesion
.extracellular matrix constituent conferring elasticity .extracellular exosome
.extracellular matrix
.collagen trimer
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
blood16
bone13
bone marrow20
brain40
connective tissue20
embryonic tissue4
eye38
heart55
intestine64
kidney42
larynx42
liver29
lung20
lymph node55
mammary gland19
mouth30
muscle37
nerve64
ovary39
pancreas46
placenta17
skin9
spleen74
stomach62
testis9
uterus56
vascular19
Health State
TissuesTPM*
normal23
breast (mammary gland) tumor21
chondrosarcoma24
colorectal tumor79
gastrointestinal tumor50
germ cell tumor41
head and neck tumor14
kidney tumor43
leukemia10
liver tumor41
lung tumor29
lymphoma13
ovarian tumor52
retinoblastoma43
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult23
embryoid body14
blastocyst16
fetus25
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.6
adrenal gland32.9
appendix24.7
bone marrow73.9
cerebral cortex22.6
colon27.1
duodenum39
esophagus18
gallbladder32.1
heart muscle16.4
kidney27.7
liver23.8
lung28.5
lymph node29.9
ovary27.6
pancreas64.4
placenta31.9
prostate32.6
salivary gland38.4
skin21.2
small intestine35.6
spleen29.9
stomach41
testis49.3
thyroid gland33.7
urinary bladder39.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614394, gene) Intraflagellar transport 20, chlamydomonas, homolog of: ift20OMIM


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