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> Protein (NX_Q8IYX3)
Protein (NX_Q8IYX3)
Protein
Gene SymbolCCDC116 to neXtProt (NX_Q8IYX3)
DescriptionCoiled-coil domain-containing protein 116
Chromosome22
Location22q11.21 (21987005 ~ 21991616) to Ensembl
Sequene Features : Isoforms 3, Variants 103, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .centrosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
3 103 0
2014-09-19transcript level
2 86 0
2014-05-27transcript level
2 86 0
2014-02-25transcript level
2 86 0
2013-12-09transcript level
2 66 0
2013-11-01transcript level
2 64 0
2013-09-12transcript level
2 64 0
2013-08-17transcript level
2 64 0
2013-07-15transcript level
2 47 0
2013-06-11transcript level
2 47 0
2013-02-12transcript level
2 42 0
2012-12-20transcript level
2 42 0
2012-10-30transcript level
2 41 0
2012-10-07transcript level
2 41 0
2012-08-24transcript level
2 40 0
2012-07-28transcript level
2 40 0
2012-06-08transcript level
2 6 0
2012-05-07transcript level
2 6 0
2012-04-10transcript level
2 6 0
2012-01-13transcript level
2 6 0
2011-12-20transcript level
2 6 0
2011-11-11transcript level
2 6 0
2011-08-23transcript level
2 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8IYX3-1
1 20 0 56903.989
NX_Q8IYX3-2
6 20 0 67902.8166
NX_Q8IYX3-3
7 15 0 57147.7487
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744311,EBI-741753 NGFRAP1  
  .apoptotic signaling pathway
.neurotrophin TRK receptor signaling pathway
.regulation of cysteine-type endopeptidase activity involved in apoptotic process
  + 3 more...
.metal ion binding
.cysteine-type endopeptidase activator activity involved in apoptotic process
.cytosol
.cytoplasm
.nucleus
2 EBI-744311,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
3 EBI-744311,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
4 EBI-744311,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
5 EBI-744311,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
6 EBI-744311,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
7 EBI-744311,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain4
connective tissue6
testis45
Health State
TissuesTPM*
normal5
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult4
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis15
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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