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> Protein (NX_Q8N140)
Protein (NX_Q8N140)
Protein
Gene SymbolEID3 to neXtProt (NX_Q8N140)
DescriptionEP300-interacting inhibitor of differentiation 3
Chromosome12
Location12q23.3 (104697517 ~ 104698980) to Ensembl
Sequene Features : Isoforms 1, Variants 38, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 4 more...
.identical protein binding .Smc5-Smc6 complex
.cytoplasm
.nucleoplasm
.chromosome, telomeric region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 38 0
2014-09-19protein level
1 31 0
2014-05-27protein level
1 31 0
2014-02-25protein level
1 31 0
2013-12-09protein level
1 25 0
2013-11-01protein level
1 25 0
2013-09-12protein level
1 25 0
2013-08-17protein level
1 25 0
2013-07-15protein level
1 16 0
2013-06-11protein level
1 16 0
2013-02-12protein level
1 8 0
2012-12-20protein level
1 6 0
2012-10-30protein level
1 9 0
2012-10-07protein level
1 9 0
2012-08-24protein level
1 9 0
2012-07-28protein level
1 9 0
2012-06-08protein level
1 9 0
2012-05-07protein level
1 5 0
2012-04-10protein level
1 5 0
2012-01-13protein level
1 4 0
2011-12-20protein level
1 4 0
2011-11-11protein level
1 4 0
2011-08-23protein level
1 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N140-1
15 0 1 38143.774
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744483,EBI-740978 MAGEA1  
  .negative regulation of Notch signaling pathway
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.histone deacetylase binding .plasma membrane
.cytoplasm
.nucleus
2 EBI-744483,EBI-301834 HDAC1  
  .histone H4 deacetylation
.histone H3 deacetylation
.fungiform papilla formation
  + 34 more...
.NAD-dependent histone deacetylase activity (H3-K18 specific)
.repressing transcription factor binding
.NF-kappaB binding
  + 17 more...
.protein complex
.NuRD complex
.Sin3 complex
  + 7 more...
3 EBI-744483,EBI-5525894 EID2  
  .negative regulation of transcription, DNA-templated
.regulation of cell proliferation
.negative regulation of transforming growth factor beta receptor signaling pathway
  + 6 more...
.SMAD binding .nucleoplasm
.intracellular
4 EBI-744483,EBI-2557356 NDNL2  
  .cellular protein metabolic process
.post-translational protein modification
.regulation of growth
  + 4 more...
.N/A .Smc5-Smc6 complex
.cytoplasm
.nucleoplasm
.chromosome, telomeric region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
brain2
eye9
larynx42
lung8
lymph node22
ovary9
stomach10
testis142
Health State
TissuesTPM*
normal7
germ cell tumor22
head and neck tumor7
leukemia10
lymphoma27
Developmental Stage
TissuesTPM*
adult3
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.2
adrenal gland1.7
appendix3.6
bone marrow3.2
cerebral cortex1.5
esophagus1.6
gallbladder2.5
kidney1.4
lung1.8
lymph node5.6
ovary3.6
pancreas1.1
placenta1.5
prostate3.3
skin1.5
small intestine1.2
spleen2.4
stomach1.6
testis62.5
thyroid gland1.1
urinary bladder2.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612986, gene) E1a-like inhibitor of differentiation 3; EID3OMIM


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