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> Protein (NX_Q8N2Z9)
Protein (NX_Q8N2Z9)
Protein
Gene SymbolAPITD1 to neXtProt (NX_Q8N2Z9)
DescriptionCentromere protein S
Chromosome1
Location1p36.22 (10490159 ~ 10512210) to Ensembl
Sequene Features : Isoforms 3, Variants 27, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.CENP-A containing nucleosome assembly
.positive regulation of protein ubiquitination
  + 8 more...
.chromatin binding
.DNA binding
.FANCM-MHF complex
.Fanconi anaemia nuclear complex
.cytosol
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 27 3
2014-09-19protein level
3 20 3
2014-05-27protein level
3 20 3
2014-02-25protein level
3 20 3
2013-12-09protein level
3 15 3
2013-11-01protein level
3 14 2
2013-09-12protein level
3 14 1
2013-08-17protein level
3 14 1
2013-07-15protein level
3 6 1
2013-06-11protein level
3 6 1
2013-02-12protein level
3 3 0
2012-12-20protein level
3 3 0
2012-10-30protein level
3 3 0
2012-10-07protein level
3 3 0
2012-08-24protein level
3 3 0
2012-07-28protein level
3 3 0
2012-06-08protein level
3 3 0
2012-05-07protein level
3 2 0
2012-04-10protein level
3 2 0
2012-01-13protein level
3 2 0
2011-12-20protein level
3 2 0
2011-11-11protein level
3 2 0
2011-08-23protein level
3 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N2Z9-1
2 4 0 15882.9272
NX_Q8N2Z9-2
1 4 2 19035.3285
NX_Q8N2Z9-3
1 3 0 9068.2858
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5529649,EBI-5529694 STRA13  
  .kinetochore assembly
.cell division
.CENP-A containing nucleosome assembly
  + 6 more...
.DNA binding .FANCM-MHF complex
.Fanconi anaemia nuclear complex
.nucleoplasm
.condensed chromosome kinetochore
2 EBI-5529649,EBI-10172004 HOMEZ  
  .transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
bone13
brain21
cervix103
connective tissue73
embryonic tissue9
eye52
heart22
intestine21
kidney56
lung41
lymph node44
ovary9
pancreas18
parathyroid97
pharynx24
pituitary gland121
placenta24
prostate31
skin14
stomach10
testis105
uterus25
Health State
TissuesTPM*
normal27
cervical tumor57
chondrosarcoma36
germ cell tumor26
glioma83
kidney tumor14
leukemia10
lung tumor9
non-neoplasia41
pancreatic tumor9
prostate cancer38
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor95
uterine tumor33
Developmental Stage
TissuesTPM*
adult26
blastocyst32
fetus43
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.5
adrenal gland15.2
appendix9.9
bone marrow9.2
cerebral cortex8.5
colon13.5
duodenum20.1
esophagus10.7
gallbladder18
heart muscle7.1
kidney48.7
liver9.7
lung12
lymph node9.9
ovary8.5
pancreas8.3
placenta7.9
prostate14.1
salivary gland12.5
skin6.3
small intestine13.9
spleen6.4
stomach13.1
testis72.3
thyroid gland30
urinary bladder11.9
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*609130, gene) Apoptosis-inducing, taf9-like domain 1; APITD1OMIM


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