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> Protein (NX_Q8N3C7)
Protein (NX_Q8N3C7)
Protein
Gene SymbolCLIP4 to neXtProt (NX_Q8N3C7)
DescriptionCAP-Gly domain-containing linker protein 4
Chromosome2
Location2p23.2 (29320571 ~ 29412509) to Ensembl
Sequene Features : Isoforms 4, Variants 107, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 107 2
2014-09-19protein level
4 77 2
2014-05-27protein level
4 77 2
2014-02-25protein level
4 77 2
2013-12-09protein level
4 62 2
2013-11-01protein level
4 59 2
2013-09-12protein level
4 59 2
2013-08-17protein level
4 59 2
2013-07-15protein level
4 42 2
2013-06-11protein level
4 42 2
2013-02-12protein level
4 23 1
2012-12-20protein level
4 20 1
2012-10-30protein level
4 29 1
2012-10-07protein level
4 29 1
2012-08-24protein level
4 28 1
2012-07-28protein level
4 27 1
2012-06-08protein level
4 28 1
2012-05-07protein level
4 22 1
2012-04-10protein level
4 22 1
2012-01-13protein level
4 11 1
2011-12-20protein level
4 11 1
2011-11-11protein level
4 11 1
2011-08-23protein level
4 11 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N3C7-1
5 29 0 76268.3841
NX_Q8N3C7-2
1 28 0 65135.7675
NX_Q8N3C7-3
0 29 0 64923.6157
NX_Q8N3C7-4
2 14 0 37089.0251
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5655540,EBI-742790 TRIM32  
  .positive regulation of cell motility
.negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
.negative regulation of viral release from host cell
  + 21 more...
.ubiquitin protein ligase activity
.protein self-association
.ubiquitin binding
  + 8 more...
.striated muscle myosin thick filament
.cytosol
.cytoplasm
.nucleus
2 EBI-5655540,EBI-10265237 ZNF114  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.extracellular exosome
.nucleus
3 EBI-5655540,EBI-752007 JAKMIP2  
  .N/A .N/A .Golgi apparatus
4 EBI-5655540,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
5 EBI-5655540,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
bladder33
bone marrow20
brain43
connective tissue33
embryonic tissue9
esophagus99
eye47
heart11
intestine8
kidney14
larynx42
liver9
lung14
lymph node11
mammary gland66
mouth90
muscle56
nerve64
pancreas23
parathyroid48
pharynx49
pituitary gland181
placenta98
prostate52
skin37
testis52
thyroid42
trachea289
uterus17
vascular19
Health State
TissuesTPM*
normal39
breast (mammary gland) tumor75
chondrosarcoma24
colorectal tumor8
esophageal tumor115
germ cell tumor7
glioma27
head and neck tumor74
kidney tumor29
liver tumor20
lymphoma13
non-neoplasia72
ovarian tumor13
pancreatic tumor9
prostate cancer19
retinoblastoma43
skin tumor23
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult43
embryoid body14
neonate32
fetus16
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17.5
adrenal gland12.6
appendix13.2
bone marrow1.2
cerebral cortex16.7
colon6.3
duodenum5.2
esophagus25
gallbladder17.2
heart muscle23.9
kidney8.1
liver4.2
lung18.3
lymph node11.6
ovary23.9
pancreas2.8
placenta22.2
prostate15.6
salivary gland4.4
skin31.8
small intestine5.6
spleen10.5
stomach6.8
testis25
thyroid gland38.5
urinary bladder18.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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