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> Protein (NX_Q8N3X1)
Protein (NX_Q8N3X1)
Protein
Gene SymbolFNBP4 to neXtProt (NX_Q8N3X1)
DescriptionFormin-binding protein 4
Chromosome11
Location11p11.2 (47738072 ~ 47788995) to Ensembl
Sequene Features : Isoforms 2, Variants 113, PTMs 16 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 113 16
2014-09-19protein level
2 91 16
2014-05-27protein level
2 91 16
2014-02-25protein level
2 89 15
2013-12-09protein level
2 72 15
2013-11-01protein level
2 70 15
2013-09-12protein level
2 70 15
2013-08-17protein level
2 70 15
2013-07-15protein level
2 44 15
2013-06-11protein level
2 44 15
2013-02-12protein level
2 19 34
2012-12-20protein level
2 19 34
2012-10-30protein level
2 24 34
2012-10-07protein level
2 24 17
2012-08-24protein level
2 14 17
2012-07-28protein level
2 12 17
2012-06-08protein level
2 3 17
2012-05-07protein level
2 3 17
2012-04-10protein level
2 3 17
2012-01-13protein level
2 3 17
2011-12-20protein level
2 7 17
2011-11-11protein level
2 7 14
2011-08-23protein level
2 7 14
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N3X1-1
1 33 0 110197.9385
NX_Q8N3X1-2
2 33 0 110383.0543
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-310600,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland121
ascites150
blood98
bone55
bone marrow20
brain60
cervix123
connective tissue80
ear248
embryonic tissue93
esophagus99
eye38
heart89
intestine99
kidney23
liver73
lung62
lymph22
lymph node167
mammary gland46
mouth45
muscle56
nerve128
ovary78
pancreas18
pharynx24
pituitary gland121
placenta45
prostate52
skin28
spleen93
stomach31
testis59
thymus75
thyroid85
trachea115
uterus107
vascular77
Health State
TissuesTPM*
normal66
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor42
cervical tumor144
chondrosarcoma120
colorectal tumor133
esophageal tumor115
gastrointestinal tumor84
germ cell tumor64
glioma65
head and neck tumor59
kidney tumor14
leukemia116
liver tumor31
lung tumor58
lymphoma27
non-neoplasia82
ovarian tumor105
pancreatic tumor38
primitive neuroectodermal tumor of the CNS23
prostate cancer38
soft tissue/muscle tissue tumor15
uterine tumor133
Developmental Stage
TissuesTPM*
adult77
embryoid body114
blastocyst81
fetus95
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue37.4
adrenal gland43.7
appendix66.3
bone marrow67
cerebral cortex28
colon32.3
duodenum45.1
esophagus30.5
gallbladder44.5
heart muscle28
kidney24.6
liver18
lung50.6
lymph node69.3
ovary60.9
pancreas21.1
placenta44.5
prostate47.8
salivary gland28.7
skin61.7
small intestine43.3
spleen81.8
stomach44.9
testis31.7
thyroid gland46.3
urinary bladder36.9
Tissues
TissuesExpression level
adrenal glandLow
appendixLow
bronchusLow
cerebellumLow
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverLow
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
pancreasLow
placentaLow
rectumMedium
seminal vesicleMedium
skin 1Low
skin 2Medium
small intestineMedium
stomach 1Medium
stomach 2Low
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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