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> Protein (NX_Q8N5A5)
Protein (NX_Q8N5A5)
Protein
Gene SymbolZGPAT to neXtProt (NX_Q8N5A5)
DescriptionZinc finger CCCH-type with G patch domain-containing protein
Chromosome20
Location20q13.33 (62338817 ~ 62367494) to Ensembl
Sequene Features : Isoforms 4, Variants 66, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of transcription, DNA-templated
.negative regulation of epidermal growth factor-activated receptor activity
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 66 6
2014-09-19protein level
4 51 6
2014-05-27protein level
4 51 6
2014-02-25protein level
4 49 5
2013-12-09protein level
3 41 5
2013-11-01protein level
3 40 5
2013-09-12protein level
3 40 4
2013-08-17protein level
3 40 4
2013-07-15protein level
3 26 4
2013-06-11protein level
3 26 4
2013-02-12protein level
3 13 12
2012-12-20protein level
3 13 12
2012-10-30protein level
3 16 12
2012-10-07protein level
3 16 4
2012-08-24protein level
3 16 4
2012-07-28protein level
3 16 4
2012-06-08protein level
3 21 4
2012-05-07protein level
3 20 4
2012-04-10protein level
3 20 4
2012-01-13protein level
3 9 4
2011-12-20protein level
3 9 4
2011-11-11protein level
3 9 4
2011-08-23protein level
3 9 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N5A5-1
1 25 0 57323.4679
NX_Q8N5A5-2
1 25 0 55465.5952
NX_Q8N5A5-3
1 24 0 54571.2145
NX_Q8N5A5-4
0 9 0 20683.8486
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3439227,EBI-1237044 DHX15  
  .RNA splicing
.mRNA processing
.mRNA splicing, via spliceosome
.poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
  + 2 more...
.cytoplasm
.nucleolus
.U12-type spliceosomal complex
  + 2 more...
2 EBI-3439227,EBI-748961 CCNDBP1  
  .regulation of cell cycle
.cell cycle
.N/A .cytoplasm
.nucleoplasm
.nucleus
3 EBI-10183064,EBI-740738 LDOC1  
  .negative regulation of cell proliferation .N/A .nucleolus
.nucleus
4 EBI-3439227,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
5 EBI-3439227,EBI-739566 KRT15  
  .activation of mitophagy in response to mitochondrial depolarization
.epidermis development
.scaffold protein binding
.structural constituent of cytoskeleton
.extracellular exosome
.intermediate filament
.nucleus
6 EBI-10183064,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
7 EBI-10183064,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
8 EBI-10183064,EBI-745226 AIMP2  
  .Type II pneumocyte differentiation
.positive regulation of protein ubiquitination
.gene expression
  + 3 more...
.N/A .membrane
.cytosol
.nucleus
9 EBI-3439227,EBI-10175039 TP53BP2  
  .positive regulation of execution phase of apoptosis
.intrinsic apoptotic signaling pathway by p53 class mediator
.negative regulation of cell cycle
  + 7 more...
.NF-kappaB binding
.identical protein binding
.SH3/SH2 adaptor activity
.p53 binding
.perinuclear region of cytoplasm
.cytoplasm
.nucleus
10 EBI-3439227,EBI-2808286 CCDC57  
  .N/A .N/A .N/A
11 EBI-10183064,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
12 EBI-3439227,EBI-724373 BEND5  
  .N/A .N/A .Golgi apparatus
13 EBI-3439227,EBI-713786 PHC2  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 2 more...
.identical protein binding
.zinc ion binding
.DNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 2 more...
14 EBI-10183064,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
15 EBI-3439227,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
16 EBI-3439227,EBI-2548751 MIPOL1  
  .N/A .N/A .nucleus
17 EBI-3439227,EBI-740680 DYDC1  
  .N/A .N/A .N/A
18 EBI-3439227,EBI-742740 ZBTB8A  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
19 EBI-10183064,EBI-745680 STAC3  
  .skeletal muscle fiber development
.intracellular signal transduction
.neuromuscular synaptic transmission
.skeletal muscle contraction
.metal ion binding
.identical protein binding
.N/A
20 EBI-3439227,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
21 EBI-3439227,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
22 EBI-3439227,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
23 EBI-3439227,EBI-2548012 BLZF1  
  .Golgi to plasma membrane protein transport
.cell proliferation
.Golgi organization
  + 3 more...
.ubiquitin protein ligase binding
.enzyme binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.Golgi lumen
.cytoplasm
.nucleoplasm
  + 2 more...
24 EBI-3439227,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
25 EBI-10183064,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
26 EBI-3439227,EBI-747204 IKZF3  
  .regulation of lymphocyte differentiation
.regulation of B cell differentiation
.regulation of apoptotic process
  + 5 more...
.protein heterodimerization activity
.metal ion binding
.sequence-specific DNA binding
  + 2 more...
.plasma membrane
.cytoplasm
.nucleus
27 EBI-3439227,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
28 EBI-3439227,EBI-10187270 AMOTL2  
  .hippo signaling
.Wnt signaling pathway
.N/A .recycling endosome
.cytoplasmic vesicle
.apical plasma membrane
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites75
bladder167
blood130
bone69
brain85
cervix20
connective tissue40
embryonic tissue18
esophagus198
eye33
heart111
intestine60
kidney80
liver43
lung62
lymph22
lymph node11
mammary gland46
mouth15
muscle37
ovary39
pancreas23
placenta67
prostate42
salivary gland49
skin42
spleen280
stomach31
testis80
thymus276
thyroid64
trachea77
uterus43
vascular38
Health State
TissuesTPM*
normal65
breast (mammary gland) tumor53
chondrosarcoma36
colorectal tumor44
esophageal tumor173
gastrointestinal tumor42
germ cell tumor56
glioma74
head and neck tumor22
leukemia31
liver tumor52
lung tumor97
lymphoma13
non-neoplasia62
ovarian tumor26
pancreatic tumor28
primitive neuroectodermal tumor of the CNS62
prostate cancer9
skin tumor55
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult51
embryoid body28
blastocyst16
neonate32
fetus26
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.6
adrenal gland9.6
appendix15.5
bone marrow15.6
cerebral cortex7.7
colon8.9
duodenum12
esophagus9.9
gallbladder9.7
heart muscle8
kidney26.1
liver30.4
lung10.9
lymph node18.7
ovary7.2
pancreas7
placenta8.2
prostate11.2
salivary gland13.1
skin11.4
small intestine11.9
spleen20.9
stomach13.4
testis15.6
thyroid gland7.6
urinary bladder9.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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