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> Protein (NX_Q8N5K1)
Protein (NX_Q8N5K1)
Protein
Gene SymbolCISD2 to neXtProt (NX_Q8N5K1)
DescriptionCDGSH iron-sulfur domain-containing protein 2
Chromosome4
Location4q24 (103790135 ~ 103810399) to Ensembl
Sequene Features : Isoforms 1, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of autophagy
.multicellular organismal aging
.mitochondrion degradation
.2 iron, 2 sulfur cluster binding
.metal ion binding
.poly(A) RNA binding
.protein homodimerization activity
.protein complex
.integral component of membrane
.membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 8 2
2014-09-19protein level
1 8 2
2014-05-27protein level
1 8 2
2014-02-25protein level
1 8 2
2013-12-09protein level
1 6 2
2013-11-01protein level
1 6 1
2013-09-12protein level
1 6 1
2013-08-17protein level
1 6 1
2013-07-15protein level
1 3 0
2013-06-11protein level
1 3 0
2013-02-12protein level
1 1 1
2012-12-20protein level
1 1 1
2012-10-30protein level
1 2 1
2012-10-07protein level
1 2 1
2012-08-24protein level
1 2 1
2012-07-28protein level
1 2 1
2012-06-08protein level
1 7 1
2012-05-07protein level
1 7 1
2012-04-10protein level
1 7 1
2012-01-13protein level
1 7 1
2011-12-20protein level
1 7 1
2011-11-11protein level
1 7 1
2011-08-23protein level
1 7 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N5K1-1
8 0 0 15268.4042
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland151
bladder100
bone41
brain10
heart22
intestine8
kidney9
liver9
lung2
mammary gland6
pancreas9
placenta3
prostate10
skin4
testis6
uterus17
Health State
TissuesTPM*
normal5
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor21
cervical tumor86
chondrosarcoma12
germ cell tumor3
glioma27
liver tumor20
lung tumor9
lymphoma27
non-neoplasia10
primitive neuroectodermal tumor of the CNS31
prostate cancer19
uterine tumor22
Developmental Stage
TissuesTPM*
adult26
embryoid body14
blastocyst16
neonate64
fetus30
infant85
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.5
adrenal gland30.4
appendix21.3
bone marrow20.9
cerebral cortex20.8
colon23.7
duodenum21.7
esophagus16.1
gallbladder22.7
heart muscle13.1
kidney31.7
liver26.9
lung14.3
lymph node22.6
ovary11.2
pancreas8.4
placenta16.1
prostate18.5
salivary gland16.7
skin12.7
small intestine23.8
spleen14.9
stomach20.4
testis12.4
thyroid gland38.9
urinary bladder26.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#604928, phenotype) Wolfram syndrome 2; WFS2OMIM
2(*611507, gene) Cdgsh iron sulfur domain protein 2; CISD2OMIM


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