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> Protein (NX_Q8N7W2)
Protein (NX_Q8N7W2)
Protein
Gene SymbolBEND7 to neXtProt (NX_Q8N7W2)
DescriptionBEN domain-containing protein 7
Chromosome10
Location10p13 (13480484 ~ 13570974) to Ensembl
Sequene Features : Isoforms 3, Variants 57, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .extracellular exosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 57 2
2014-09-19protein level
3 46 2
2014-05-27protein level
3 46 2
2014-02-25protein level
3 46 2
2013-12-09protein level
3 38 2
2013-11-01protein level
3 38 2
2013-09-12protein level
3 38 2
2013-08-17protein level
3 38 2
2013-07-15protein level
3 26 2
2013-06-11protein level
3 26 2
2013-02-12protein level
3 20 6
2012-12-20protein level
3 19 6
2012-10-30protein level
3 23 6
2012-10-07protein level
3 23 2
2012-08-24protein level
3 18 2
2012-07-28protein level
3 18 2
2012-06-08protein level
3 19 2
2012-05-07protein level
3 19 2
2012-04-10protein level
3 19 2
2012-01-13protein level
3 12 2
2011-12-20protein level
3 12 2
2011-11-11protein level
3 12 0
2011-08-23protein level
3 12 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N7W2-1
3 24 0 57513.2863
NX_Q8N7W2-2
3 17 0 41339.2568
NX_Q8N7W2-3
1 23 0 51428.3217
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10181188,EBI-1210503 CHD2  
  .hematopoietic stem cell differentiation
.DNA duplex unwinding
.chromatin modification
  + 4 more...
.poly(A) RNA binding
.histone binding
.ATP binding
  + 3 more...
.extracellular exosome
.intracellular membrane-bounded organelle
.nucleolus
  + 2 more...
2 EBI-10181188,EBI-696621 PIM1  
  .vitamin D receptor signaling pathway
.protein autophosphorylation
.negative regulation of sequence-specific DNA binding transcription factor activity
  + 9 more...
.ribosomal small subunit binding
.manganese ion binding
.transcription factor binding
  + 2 more...
.plasma membrane
.cytoplasm
.nucleus
3 EBI-10181188,EBI-351257 DDX6  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.cytoplasmic mRNA processing body assembly
.viral RNA genome packaging
  + 4 more...
.poly(A) RNA binding
.protein domain specific binding
.ATP binding
  + 3 more...
.intracellular membrane-bounded organelle
.RISC complex
.membrane
  + 5 more...
4 EBI-10181188,EBI-489887 EMD  
  .cellular response to growth factor stimulus
.regulation of canonical Wnt signaling pathway
.negative regulation of fibroblast proliferation
  + 8 more...
.beta-tubulin binding
.actin binding
.nuclear membrane
.integral component of membrane
.membrane
  + 5 more...
5 EBI-10181188,EBI-10212306 SMARCA2  
  .positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
  + 9 more...
.transcription regulatory region DNA binding
.DNA-dependent ATPase activity
.ATP binding
  + 3 more...
.nBAF complex
.npBAF complex
.intermediate filament cytoskeleton
  + 5 more...
6 EBI-10181188,EBI-1048159 MFAP1  
  .extracellular matrix organization .poly(A) RNA binding .extracellular region
.microfibril
7 EBI-10181188,EBI-396072 PPIG  
  .RNA splicing
.protein folding
.protein peptidyl-prolyl isomerization
.poly(A) RNA binding
.cyclosporin A binding
.peptidyl-prolyl cis-trans isomerase activity
.nuclear speck
.nuclear matrix
.cytoplasm
  + 2 more...
8 EBI-10181188,EBI-358049 BYSL  
  .cell proliferation
.female pregnancy
.cell adhesion
  + 2 more...
.poly(A) RNA binding .apical part of cell
.intracellular membrane-bounded organelle
.membrane
  + 3 more...
9 EBI-10181188,EBI-399257 MORF4L2  
  .positive regulation of striated muscle cell differentiation
.positive regulation of transcription from RNA polymerase II promoter
.regulation of growth
  + 4 more...
.N/A .nucleolus
.nucleoplasm
10 EBI-10181188,EBI-3920396 C11orf57  
  .N/A .N/A .N/A
11 EBI-10181188,EBI-10268158 FAM133A  
  .N/A .N/A .N/A
12 EBI-10181188,EBI-750700 EIF1AD  
  .N/A .translation initiation factor activity .intermediate filament cytoskeleton
.intracellular membrane-bounded organelle
.nucleoplasm
13 EBI-10181188,EBI-597063 ZCCHC10  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
14 EBI-10181188,EBI-1245604 EAF2  
  .negative regulation of epithelial cell proliferation involved in prostate gland development
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of cell growth
.apoptotic process
.RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II regulatory region sequence-specific DNA binding
.ELL-EAF complex
.nuclear speck
.transcription elongation factor complex
15 EBI-10181188,EBI-5278764 CDCA7L  
  .positive regulation of cell proliferation
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .cytoplasm
.nucleolus
.nucleus
16 EBI-10181188,EBI-769261 EAF1  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .ELL-EAF complex
.nuclear speck
.Cajal body
  + 3 more...
17 EBI-10181188,EBI-10292696 CIB3  
  .N/A .calcium ion binding .N/A
18 EBI-10181188,EBI-744115 CEP44  
  .N/A .N/A .midbody
.centrosome
.cytoplasm
.spindle pole
19 EBI-743382,EBI-740897 NIF3L1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription, DNA-templated
.neuron differentiation
.identical protein binding
.transcription factor binding
.mitochondrion
.cytoplasm
.nucleus
20 EBI-10181188,EBI-713507 LYAR  
  .N/A .metal ion binding
.poly(A) RNA binding
.nucleolus
.nucleus
21 EBI-10181188,EBI-399246 MORF4L1  
  .histone H2A acetylation
.histone H4 acetylation
.regulation of growth
  + 6 more...
.protein N-terminus binding
.chromatin binding
.NuA4 histone acetyltransferase complex
.Sin3 complex
.nucleoplasm
22 EBI-10181188,EBI-2511991 USP20  
  .protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.regulation of proteasomal protein catabolic process
  + 4 more...
.zinc ion binding
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.G-protein coupled receptor binding
.perinuclear region of cytoplasm
.centrosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
bone27
brain7
connective tissue6
embryonic tissue4
eye71
intestine8
kidney75
liver14
lung5
muscle18
ovary9
pancreas23
parathyroid97
placenta14
stomach20
testis41
trachea38
uterus30
Health State
TissuesTPM*
normal21
adrenal tumor79
chondrosarcoma36
colorectal tumor8
gastrointestinal tumor16
germ cell tumor22
glioma18
liver tumor10
ovarian tumor26
soft tissue/muscle tissue tumor7
uterine tumor77
Developmental Stage
TissuesTPM*
adult15
fetus28
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.8
adrenal gland6.7
appendix3.6
bone marrow1.5
cerebral cortex5.6
colon9.5
duodenum23.2
esophagus3.7
gallbladder9.8
heart muscle4.9
kidney26.5
liver7.4
lung10
lymph node2
ovary9
pancreas8.3
placenta6.3
prostate4.6
salivary gland10.4
skin1.2
small intestine30.5
spleen2.9
stomach12.6
testis24.8
thyroid gland33
urinary bladder4.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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