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> Protein (NX_Q8N983)
Protein (NX_Q8N983)
Protein
Gene SymbolMRPL43 to neXtProt (NX_Q8N983)
Description39S ribosomal protein L43, mitochondrial
Chromosome10
Location10q24.31 (102729215 ~ 102747272) to Ensembl
Sequene Features : Isoforms 6, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mitochondrial translational termination
.mitochondrial translational elongation
.mitochondrial translational initiation
  + 3 more...
.poly(A) RNA binding
.structural constituent of ribosome
.mitochondrial ribosome
.mitochondrial inner membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
6 28 0
2014-09-19protein level
6 20 0
2014-05-27protein level
6 19 0
2014-02-25protein level
4 16 0
2013-12-09protein level
4 11 0
2013-11-01protein level
4 11 0
2013-09-12protein level
4 11 0
2013-08-17protein level
4 11 0
2013-07-15protein level
4 6 0
2013-06-11protein level
4 6 0
2013-02-12protein level
4 5 0
2012-12-20protein level
4 6 0
2012-10-30protein level
4 6 0
2012-10-07protein level
4 6 0
2012-08-24protein level
4 5 0
2012-07-28protein level
4 5 0
2012-06-08protein level
4 5 0
2012-05-07protein level
4 5 0
2012-04-10protein level
4 5 0
2012-01-13protein level
4 1 0
2011-12-20protein level
4 1 0
2011-11-11protein level
4 1 0
2011-08-23protein level
4 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N983-1
1 7 0 23416.0981
NX_Q8N983-2
1 7 0 22565.5965
NX_Q8N983-3
1 6 0 18299.4983
NX_Q8N983-4
1 6 0 17842.2022
NX_Q8N983-6
1 8 0 25846.1862
NX_Q8N983-7
2 8 0 28657.4429
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1043145,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood81
bone125
bone marrow20
brain41
cervix61
connective tissue6
ear124
embryonic tissue65
eye67
heart89
intestine60
kidney37
larynx85
liver29
lung74
lymph112
lymph node55
mammary gland26
muscle94
nerve193
ovary88
pancreas126
parathyroid97
pharynx196
placenta95
prostate84
skin109
spleen18
stomach31
testis50
thyroid21
tonsil117
uterus99
vascular38
Health State
TissuesTPM*
normal61
breast (mammary gland) tumor42
cervical tumor86
chondrosarcoma48
colorectal tumor44
germ cell tumor26
glioma102
head and neck tumor74
leukemia116
liver tumor31
lung tumor29
lymphoma138
non-neoplasia51
ovarian tumor105
pancreatic tumor85
primitive neuroectodermal tumor of the CNS133
prostate cancer57
skin tumor135
soft tissue/muscle tissue tumor119
uterine tumor99
Developmental Stage
TissuesTPM*
adult69
embryoid body71
blastocyst113
fetus70
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue38.1
adrenal gland48.7
appendix37.3
bone marrow23.6
cerebral cortex29.1
colon38.5
duodenum41.6
esophagus41.3
gallbladder47.2
heart muscle39.7
kidney64.2
liver34.3
lung41.1
lymph node43.5
ovary59.6
pancreas37.3
placenta39.1
prostate55.3
salivary gland56.2
skin38.7
small intestine37.4
spleen39.2
stomach44.4
testis70.9
thyroid gland71.8
urinary bladder48.9
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*611848, gene) Mitochondrial ribosomal protein l43; MRPL43OMIM


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