Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q8N9N5)
Protein (NX_Q8N9N5)
Protein
Gene SymbolBANP to neXtProt (NX_Q8N9N5)
DescriptionProtein BANP
Chromosome16
Location16q24.2 (87982850 ~ 88110924) to Ensembl
Sequene Features : Isoforms 7, Variants 50, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of protein catabolic process
.protein localization to nucleus
.chromatin modification
  + 4 more...
.DNA binding .nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
7 50 3
2014-09-19protein level
7 34 3
2014-05-27protein level
7 34 3
2014-02-25protein level
7 34 2
2013-12-09protein level
7 28 2
2013-11-01protein level
7 28 2
2013-09-12protein level
7 28 2
2013-08-17protein level
7 28 2
2013-07-15protein level
7 13 2
2013-06-11protein level
7 13 2
2013-02-12protein level
6 5 6
2012-12-20protein level
6 5 6
2012-10-30protein level
6 5 6
2012-10-07protein level
6 5 1
2012-08-24protein level
6 5 1
2012-07-28protein level
6 5 1
2012-06-08protein level
6 1 1
2012-05-07protein level
5 1 1
2012-04-10protein level
4 1 1
2012-01-13protein level
4 1 1
2011-12-20protein level
4 1 1
2011-11-11protein level
4 1 0
2011-08-23protein level
4 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N9N5-1
1 15 0 56459.0326
NX_Q8N9N5-2
0 12 0 51211.2774
NX_Q8N9N5-3
1 11 0 48373.0822
NX_Q8N9N5-4
0 14 0 53493.5164
NX_Q8N9N5-5
1 13 0 54208.8323
NX_Q8N9N5-6
0 12 0 50873.083
NX_Q8N9N5-7
0 15 0 55467.4509
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744695,EBI-10173222 DCDC2B  
  .intracellular signal transduction .N/A .N/A
2 EBI-744695,EBI-750973 PSMD9  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.proteasome regulatory particle assembly
  + 26 more...
.bHLH transcription factor binding
.transcription coactivator activity
.proteasome regulatory particle
.cytosol
.cytoplasm
  + 2 more...
3 EBI-744695,EBI-7600166 SLC16A3  
  .transmembrane transport
.leukocyte migration
.small molecule metabolic process
  + 5 more...
.poly(A) RNA binding
.secondary active monocarboxylate transmembrane transporter activity
.symporter activity
  + 2 more...
.nuclear membrane
.membrane
.actin cytoskeleton
  + 2 more...
4 EBI-744695,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
5 EBI-744695,EBI-948613 TOX4  
  .regulation of transcription, DNA-templated
.chromatin remodeling
.chromatin binding
.DNA binding
.PTW/PP1 phosphatase complex
.nucleoplasm
.chromatin
6 EBI-744695,EBI-366083 TP53  
  .positive regulation of intrinsic apoptotic signaling pathway
.positive regulation of reactive oxygen species metabolic process
.negative regulation of reactive oxygen species metabolic process
  + 99 more...
.protein phosphatase 2A binding
.chaperone binding
.protein N-terminus binding
  + 27 more...
.protein complex
.PML body
.nuclear matrix
  + 11 more...
7 EBI-744695,EBI-696621 PIM1  
  .vitamin D receptor signaling pathway
.protein autophosphorylation
.negative regulation of sequence-specific DNA binding transcription factor activity
  + 9 more...
.ribosomal small subunit binding
.manganese ion binding
.transcription factor binding
  + 2 more...
.plasma membrane
.cytoplasm
.nucleus
8 EBI-744695,EBI-372475 SNRPB  
  .activation of mitophagy in response to mitochondrial depolarization
.ncRNA metabolic process
.mRNA 3'-end processing
  + 9 more...
.histone pre-mRNA DCP binding
.poly(A) RNA binding
.histone pre-mRNA 3'end processing complex
.catalytic step 2 spliceosome
.U2-type prespliceosome
  + 14 more...
9 EBI-744695,EBI-2821024 TNXB  
  .elastic fiber assembly
.regulation of JUN kinase activity
.extracellular fibril organization
  + 8 more...
.heparin binding
.integrin binding
.extracellular exosome
.intracellular
.extracellular space
.proteinaceous extracellular matrix
10 EBI-744695,EBI-2115743 ALAS2  
  .small molecule metabolic process
.hemoglobin biosynthetic process
.oxygen homeostasis
  + 6 more...
.coenzyme binding
.pyridoxal phosphate binding
.glycine binding
.5-aminolevulinate synthase activity
.mitochondrial matrix
.mitochondrial inner membrane
.mitochondrion
11 EBI-744695,EBI-359252 PPIB  
  .chaperone-mediated protein folding
.bone development
.protein stabilization
  + 5 more...
.RNA polymerase binding
.unfolded protein binding
.poly(A) RNA binding
  + 3 more...
.extracellular exosome
.perinuclear region of cytoplasm
.melanosome
  + 7 more...
12 EBI-744695,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
13 EBI-744695,EBI-5544229 PPIF  
  .negative regulation of intrinsic apoptotic signaling pathway
.negative regulation of oxidative phosphorylation uncoupler activity
.regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
  + 16 more...
.cyclosporin A binding
.peptidyl-prolyl cis-trans isomerase activity
.membrane
.mitochondrial matrix
.mitochondrial inner membrane
14 EBI-744695,EBI-953909 PPIC  
  .protein folding
.protein peptidyl-prolyl isomerization
.cyclosporin A binding
.peptidyl-prolyl cis-trans isomerase activity
.extracellular exosome
.cytoplasm
15 EBI-744695,EBI-751711 MAX  
  .cellular response to peptide hormone stimulus
.retina development in camera-type eye
.neuron apoptotic process
  + 6 more...
.sequence-specific DNA binding
.transcription coactivator activity
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
.MLL1 complex
.dendrite
.PML body
  + 3 more...
16 EBI-744695,EBI-2798728 LMO4  
  .regulation of cell activation
.thymus development
.positive regulation of transcription from RNA polymerase II promoter
  + 8 more...
.zinc ion binding
.transcription factor binding
.sequence-specific DNA binding transcription factor activity
.enhancer sequence-specific DNA binding
.transcription factor complex
17 EBI-744695,EBI-359527 POLR2L  
  .positive regulation of viral transcription
.negative regulation of gene expression, epigenetic
.innate immune response
  + 23 more...
.zinc ion binding
.DNA-directed RNA polymerase activity
.DNA binding
.cytosol
.DNA-directed RNA polymerase I complex
.DNA-directed RNA polymerase III complex
  + 3 more...
18 EBI-744695,EBI-8651703 SP2  
  .cardiovascular system development
.embryonic organ development
.fibroblast proliferation
  + 5 more...
.metal ion binding
.histone deacetylase binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleoplasm
.nucleus
19 EBI-744695,EBI-492564 MAP2K1  
  .regulation of early endosome to late endosome transport
.activation of mitophagy in response to mitochondrial depolarization
.cellular senescence
  + 55 more...
.protein N-terminus binding
.protein serine/threonine kinase activator activity
.protein C-terminus binding
  + 7 more...
.extracellular exosome
.perinuclear region of cytoplasm
.perikaryon
  + 15 more...
20 EBI-744695,EBI-2528309 COL10A1  
  .cartilage development
.collagen catabolic process
.extracellular matrix organization
  + 3 more...
.metal ion binding .cell cortex
.endoplasmic reticulum lumen
.collagen trimer
  + 2 more...
21 EBI-744695,EBI-2349743 TROAP  
  .cell adhesion .N/A .cytoplasm
22 EBI-744695,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
23 EBI-744695,EBI-723426 MRPL28  
  .mitochondrial translational termination
.mitochondrial translational elongation
.mitochondrial translational initiation
  + 3 more...
.poly(A) RNA binding
.structural constituent of ribosome
.mitochondrial ribosome
.mitochondrial inner membrane
.mitochondrion
  + 2 more...
24 EBI-744695,EBI-77818 ADAM15  
  .negative regulation of receptor binding
.protein kinase C signaling
.cardiac epithelial to mesenchymal transition
  + 11 more...
.SH3 domain binding
.zinc ion binding
.metallopeptidase activity
  + 2 more...
.extracellular exosome
.cell projection
.integral component of membrane
  + 4 more...
25 EBI-744695,EBI-351018 CAMK2D  
  .negative regulation of sodium ion transmembrane transporter activity
.regulation of generation of L-type calcium current
.negative regulation of sodium ion transmembrane transport
  + 41 more...
.ion channel binding
.protein homodimerization activity
.titin binding
  + 5 more...
.perinuclear region of cytoplasm
.axon initial segment
.neuronal cell body
  + 12 more...
26 EBI-744695,EBI-701903 FHL2  
  .heart trabecula formation
.ventricular cardiac muscle cell development
.atrial cardiac muscle cell development
  + 9 more...
.androgen receptor binding
.identical protein binding
.zinc ion binding
  + 2 more...
.M band
.Z disc
.actin cytoskeleton
  + 3 more...
27 EBI-744695,EBI-6654703 RBM39  
  .RNA splicing
.mRNA processing
.RNA processing
  + 2 more...
.poly(A) RNA binding
.nucleotide binding
.nuclear speck
.microtubule cytoskeleton
.microtubule organizing center
.nucleoplasm
28 EBI-744695,EBI-2108053 NEDD9  
  .cell division
.actin filament bundle assembly
.regulation of growth
  + 5 more...
.N/A .lamellipodium
.cell cortex
.focal adhesion
  + 5 more...
29 EBI-744695,EBI-740767 ZC2HC1C  
  .N/A .metal ion binding .N/A
30 EBI-744695,EBI-10244652 EPHA10  
  .ephrin receptor signaling pathway
.axon guidance
.ATP binding
.transmembrane-ephrin receptor activity
.ephrin receptor activity
.extracellular exosome
.integral component of membrane
.integral component of plasma membrane
.plasma membrane
31 EBI-744695,EBI-3893327 FAM117B  
  .N/A .N/A .N/A
32 EBI-744695,EBI-946029 C1orf94  
  .N/A .N/A .N/A
33 EBI-744695,EBI-7317823 C22orf39  
  .N/A .N/A .N/A
34 EBI-744695,EBI-10253815 FOXR1  
  .cell differentiation
.anatomical structure morphogenesis
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.sequence-specific DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
35 EBI-744695,EBI-10256685 PID1  
  .negative regulation of glucose import in response to insulin stimulus
.positive regulation of ATP biosynthetic process
.negative regulation of ATP biosynthetic process
  + 19 more...
.N/A .cytoplasm
.nucleoplasm
36 EBI-744695,EBI-1389308 POGZ  
  .kinetochore assembly
.cell division
.mitotic sister chromatid cohesion
.metal ion binding
.DNA binding
.cytoplasm
.nucleoplasm
.nucleus
.nuclear chromatin
37 EBI-744695,EBI-6658203 FAM90A1  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
38 EBI-744695,EBI-749051 C6orf165  
  .N/A .N/A .N/A
39 EBI-744695,EBI-752049 FAM71C  
  .N/A .N/A .N/A
40 EBI-744695,EBI-10182121 ZMIZ2  
  .positive regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.ligand-dependent nuclear receptor transcription coactivator activity
.zinc ion binding
.nuclear replication fork
.mitochondrion
.nucleoplasm
.nucleus
41 EBI-744695,EBI-10271580 CCDC26  
  .N/A .N/A .N/A
42 EBI-744695,EBI-742259 LMO3  
  .positive regulation of glucocorticoid receptor signaling pathway
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of fat cell differentiation
  + 3 more...
.zinc ion binding .cytoplasm
43 EBI-744695,EBI-742887 CEP76  
  .regulation of centriole replication
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .protein complex
.cytosol
.centriole
.centrosome
44 EBI-744695,EBI-10274069 LGALS14  
  .positive regulation of T cell apoptotic process
.apoptotic process
.carbohydrate binding .nucleus
45 EBI-744695,EBI-2130111 SH3RF2  
  .protein ubiquitination
.negative regulation of phosphatase activity
.phosphatase binding
.ligase activity
.zinc ion binding
  + 2 more...
.nucleoplasm
46 EBI-744695,EBI-2865743 LACE1  
  .N/A .ATP binding .mitochondrion
47 EBI-744695,EBI-10277181 DNAJA4  
  .negative regulation of inclusion body assembly
.protein refolding
.response to heat
.chaperone binding
.unfolded protein binding
.metal ion binding
.ATP binding
.membrane
.cytosol
48 EBI-744695,EBI-740322 RBPMS  
  .positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
49 EBI-744695,EBI-2371750 GFM2  
  .mitochondrial translational termination
.ribosome disassembly
.mitochondrial translation
.organelle organization
.GTP binding
.GTPase activity
.mitochondrial matrix
50 EBI-744695,EBI-745085 PHF21A  
  .chromatin modification
.blood coagulation
.regulation of transcription, DNA-templated
  + 4 more...
.zinc ion binding
.chromatin binding
.DNA binding
.nucleoplasm
.histone deacetylase complex
51 EBI-744695,EBI-726510 LENG1  
  .N/A .N/A .N/A
52 EBI-744695,EBI-2686809 L3MBTL3  
  .erythrocyte maturation
.granulocyte differentiation
.macrophage differentiation
  + 3 more...
.N/A .nucleus
53 EBI-744695,EBI-948288 ZNF488  
  .positive regulation of oligodendrocyte differentiation
.negative regulation of transcription, DNA-templated
.oligodendrocyte development
  + 2 more...
.metal ion binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
54 EBI-744695,EBI-747844 RAB3IP  
  .positive regulation of GTPase activity
.cilium assembly
.protein localization to organelle
  + 3 more...
.Rab guanyl-nucleotide exchange factor activity .ciliary basal body
.lamellipodium
.cytoskeleton
  + 3 more...
55 EBI-744695,EBI-3913975 NRIP2  
  .transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.aspartic-type endopeptidase activity .cytoplasm
.nucleus
56 EBI-744695,EBI-3650647 TRAF4  
  .positive regulation of protein homodimerization activity
.positive regulation of JNK cascade
.positive regulation of protein kinase activity
  + 6 more...
.WW domain binding
.thioesterase binding
.ubiquitin protein ligase binding
  + 4 more...
.perinuclear region of cytoplasm
.tight junction
.plasma membrane
  + 3 more...
57 EBI-744695,EBI-1047335 ISCU  
  .protein maturation by iron-sulfur cluster transfer
.[2Fe-2S] cluster assembly
.small molecule metabolic process
  + 3 more...
.4 iron, 4 sulfur cluster binding
.2 iron, 2 sulfur cluster binding
.iron-sulfur transferase activity
  + 3 more...
.cytosol
.mitochondrial matrix
.mitochondrion
  + 2 more...
58 EBI-744695,EBI-2340004 XAGE1A  
  .N/A .N/A .N/A
59 EBI-744695,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
60 EBI-744695,EBI-356517 BAG5  
  .negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
.regulation of cellular response to heat
.regulation of inclusion body assembly
  + 7 more...
.chaperone binding
.ubiquitin protein ligase binding
.protein kinase binding
.perinuclear region of cytoplasm
.inclusion body
.membrane
  + 3 more...
61 EBI-744695,EBI-347416 LSM2  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
.RNA splicing
  + 2 more...
.poly(A) RNA binding
.Ral GTPase binding
.U6 snRNA binding
.catalytic step 2 spliceosome
.cytosol
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites50
bladder33
blood114
bone27
bone marrow41
brain38
cervix61
connective tissue13
ear124
embryonic tissue51
eye9
heart44
intestine30
kidney28
liver53
lung26
lymph node11
mammary gland19
mouth30
muscle28
nerve64
pancreas18
placenta67
prostate10
skin61
spleen74
stomach20
testis45
thymus150
trachea77
uterus17
vascular19
Health State
TissuesTPM*
normal39
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma24
colorectal tumor17
gastrointestinal tumor25
germ cell tumor75
glioma37
head and neck tumor7
leukemia52
liver tumor114
lung tumor19
lymphoma41
non-neoplasia20
pancreatic tumor9
primitive neuroectodermal tumor of the CNS78
prostate cancer9
skin tumor95
soft tissue/muscle tissue tumor31
uterine tumor22
Developmental Stage
TissuesTPM*
adult31
embryoid body71
blastocyst16
neonate32
fetus39
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.7
adrenal gland7.7
appendix9.1
bone marrow10.7
cerebral cortex5
colon6.1
duodenum4.3
esophagus6.2
gallbladder6.9
heart muscle5.1
kidney6.7
liver7.4
lung6.9
lymph node11.4
ovary11.2
pancreas3.8
placenta12.9
prostate5.8
salivary gland5.4
skin6.6
small intestine6.9
spleen9.8
stomach6.2
testis11.3
thyroid gland7.9
urinary bladder8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611564, gene) Btg3-associated nuclear protein; BANPOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center