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> Protein (NX_Q8N9Q2)
Protein (NX_Q8N9Q2)
Protein
Gene SymbolSREK1IP1 to neXtProt (NX_Q8N9Q2)
DescriptionProtein SREK1IP1
Chromosome5
Location5q12.3 (64013971 ~ 64064512) to Ensembl
Sequene Features : Isoforms 1, Variants 19, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.RNA splicing
.mRNA processing
.zinc ion binding
.nucleic acid binding
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 19 3
2014-09-19protein level
1 18 3
2014-05-27protein level
1 18 3
2014-02-25protein level
1 17 3
2013-12-09protein level
1 16 3
2013-11-01protein level
1 14 3
2013-09-12protein level
1 14 3
2013-08-17protein level
1 14 3
2013-07-15protein level
1 10 3
2013-06-11protein level
1 10 3
2013-02-12protein level
1 3 9
2012-12-20protein level
1 3 9
2012-10-30protein level
1 3 9
2012-10-07protein level
1 3 9
2012-08-24protein level
1 1 9
2012-07-28protein level
1 1 9
2012-06-08protein level
1 1 9
2012-05-07protein level
1 1 9
2012-04-10protein level
1 1 9
2012-01-13protein level
1 1 9
2011-12-20protein level
1 1 9
2011-11-11protein level
1 1 9
2011-08-23protein level
1 1 9
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8N9Q2-1
5 0 0 18165.5502
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10268630,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
2 EBI-10268630,EBI-741141 NME1  
  .cellular response to fatty acid
.cellular response to glucose stimulus
.nucleobase-containing small molecule metabolic process
  + 22 more...
.poly(A) RNA binding
.ribosomal small subunit binding
.identical protein binding
  + 7 more...
.extracellular exosome
.perinuclear region of cytoplasm
.ruffle membrane
  + 7 more...
3 EBI-10268630,EBI-395290 RBM39  
  .RNA splicing
.mRNA processing
.RNA processing
  + 2 more...
.poly(A) RNA binding
.nucleotide binding
.nuclear speck
.microtubule cytoskeleton
.microtubule organizing center
.nucleoplasm
4 EBI-10268630,EBI-724333 PPCDC  
  .small molecule metabolic process
.pantothenate metabolic process
.coenzyme A biosynthetic process
  + 3 more...
.phosphopantothenoylcysteine decarboxylase activity .cytosol
5 EBI-10268630,EBI-745680 STAC3  
  .skeletal muscle fiber development
.intracellular signal transduction
.neuromuscular synaptic transmission
.skeletal muscle contraction
.metal ion binding
.identical protein binding
.N/A
6 EBI-10268630,EBI-742664 HSD17B14  
  .steroid catabolic process .testosterone 17-beta-dehydrogenase (NADP+) activity
.estradiol 17-beta-dehydrogenase activity
.cytosol
7 EBI-10268630,EBI-742426 SDCBP2  
  .intracellular transport
.intracellular signal transduction
.nervous system development
.protein heterodimerization activity
.protein homodimerization activity
.protein C-terminus binding
.extracellular exosome
.plasma membrane
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
blood8
bone27
brain6
connective tissue6
embryonic tissue32
eye28
intestine21
kidney47
liver29
lung29
lymph22
lymph node89
mammary gland19
mouth30
muscle56
ovary19
pancreas42
parathyroid48
pituitary gland60
placenta24
prostate42
spleen18
testis16
uterus47
Health State
TissuesTPM*
normal30
adrenal tumor79
bladder carcinoma56
chondrosarcoma24
colorectal tumor26
gastrointestinal tumor16
germ cell tumor49
glioma9
kidney tumor43
leukemia21
liver tumor20
lung tumor19
lymphoma13
non-neoplasia31
ovarian tumor26
pancreatic tumor9
primitive neuroectodermal tumor of the CNS47
prostate cancer9
retinoblastoma21
soft tissue/muscle tissue tumor23
uterine tumor44
Developmental Stage
TissuesTPM*
adult30
embryoid body57
blastocyst16
fetus32
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.4
adrenal gland8.1
appendix7.9
bone marrow14.4
cerebral cortex4.9
colon7.3
duodenum6.6
esophagus14.2
gallbladder8.8
heart muscle6
kidney7
liver5
lung8.7
lymph node8.7
ovary8.5
pancreas2.6
placenta10.3
prostate7.6
salivary gland5.9
skin14.7
small intestine5.8
spleen8.5
stomach6.5
testis7.6
thyroid gland9.7
urinary bladder7.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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