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> Protein (NX_Q8NA54)
Protein (NX_Q8NA54)
Protein
Gene SymbolIQUB to neXtProt (NX_Q8NA54)
DescriptionIQ and ubiquitin-like domain-containing protein
Chromosome7
Location7q31.32 (123092454 ~ 123175131) to Ensembl
Sequene Features : Isoforms 2, Variants 136, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cilium morphogenesis
.smoothened signaling pathway
.N/A .motile cilium
.acrosomal vesicle
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 136 0
2014-09-19protein level
2 101 0
2014-05-27protein level
2 101 0
2014-02-25protein level
2 101 0
2013-12-09protein level
2 83 0
2013-11-01protein level
2 77 0
2013-09-12protein level
2 77 0
2013-08-17protein level
2 77 0
2013-07-15protein level
2 52 0
2013-06-11protein level
2 52 0
2013-02-12protein level
2 24 0
2012-12-20protein level
2 23 0
2012-10-30protein level
2 28 0
2012-10-07protein level
2 28 0
2012-08-24protein level
2 22 0
2012-07-28protein level
2 22 0
2012-06-08protein level
2 25 0
2012-05-07protein level
2 25 0
2012-04-10protein level
2 25 0
2012-01-13protein level
2 14 0
2011-12-20protein level
2 14 0
2011-11-11protein level
2 14 0
2011-08-23protein level
2 14 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NA54-1
10 26 0 92523.0112
NX_Q8NA54-2
1 26 0 69338.355
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10220600,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-10220600,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
3 EBI-10220600,EBI-1045155 MAGEA6  
  .N/A .N/A .N/A
4 EBI-10220600,EBI-10176396 KRTAP12-4  
  .N/A .N/A .keratin filament
5 EBI-10220600,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
6 EBI-10220600,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
7 EBI-10220600,EBI-349105 DYNLL1  
  .positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
.intrinsic apoptotic signaling pathway
.negative regulation of phosphorylation
  + 15 more...
.nitric-oxide synthase regulator activity
.motor activity
.ciliary tip
.mitotic spindle
.primary cilium
  + 11 more...
8 EBI-10220600,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
9 EBI-10220600,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
10 EBI-10220600,EBI-8638439 CCDC36  
  .positive regulation of defense response to virus by host .N/A .N/A
11 EBI-10220600,EBI-6872807 SYCE1  
  .cell division
.synaptonemal complex assembly
.N/A .central element
12 EBI-10220600,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
13 EBI-10220600,EBI-2548012 BLZF1  
  .Golgi to plasma membrane protein transport
.cell proliferation
.Golgi organization
  + 3 more...
.ubiquitin protein ligase binding
.enzyme binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.Golgi lumen
.cytoplasm
.nucleoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain1
connective tissue6
kidney4
lung2
spleen18
testis142
trachea38
Health State
TissuesTPM*
normal12
germ cell tumor3
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult1
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
kidney2.9
lung1.2
testis35.6
thyroid gland2.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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