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> Protein (NX_Q8NA61)
Protein (NX_Q8NA61)
Protein
Gene SymbolSPERT to neXtProt (NX_Q8NA61)
DescriptionSpermatid-associated protein
Chromosome13
Location13q14.13 (46276446 ~ 46288694) to Ensembl
Sequene Features : Isoforms 2, Variants 70, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .cytoplasmic membrane-bounded vesicle
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 70 0
2014-09-19protein level
2 52 0
2014-05-27transcript level
2 52 0
2014-02-25transcript level
2 51 0
2013-12-09transcript level
2 42 0
2013-11-01transcript level
2 40 0
2013-09-12transcript level
2 40 0
2013-08-17transcript level
2 40 0
2013-07-15transcript level
2 21 0
2013-06-11transcript level
2 21 0
2013-02-12transcript level
2 11 0
2012-12-20transcript level
2 12 0
2012-10-30transcript level
2 13 0
2012-10-07transcript level
2 13 0
2012-08-24transcript level
2 12 0
2012-07-28transcript level
2 12 0
2012-06-08transcript level
2 13 0
2012-05-07transcript level
2 10 0
2012-04-10transcript level
2 10 0
2012-01-13transcript level
2 3 0
2011-12-20transcript level
2 3 0
2011-11-11transcript level
2 3 0
2011-08-23transcript level
2 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NA61-1
3 20 0 51537.9497
NX_Q8NA61-2
1 20 0 47258.6967
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741724,EBI-725515 FRS3  
  .fibroblast growth factor receptor signaling pathway
.signal transduction
.fibroblast growth factor receptor binding .plasma membrane
2 EBI-741724,EBI-398610 EIF4E2  
  .cytokine-mediated signaling pathway
.negative regulation of translation
.in utero embryonic development
.poly(A) RNA binding
.ubiquitin protein ligase binding
.translation factor activity, RNA binding
  + 2 more...
.mRNA cap binding complex
.cytosol
3 EBI-741724,EBI-3922653 DUSP14  
  .peptidyl-tyrosine dephosphorylation .poly(A) RNA binding
.MAP kinase tyrosine/serine/threonine phosphatase activity
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.N/A
4 EBI-741724,EBI-1757866 MOS  
  .negative regulation of metaphase/anaphase transition of meiotic cell cycle
.establishment of meiotic spindle orientation
.protein autophosphorylation
  + 6 more...
.ATP binding
.MAP kinase kinase kinase activity
.protein serine/threonine kinase activity
.cytoplasm
5 EBI-741724,EBI-351710 ACTN1  
  .regulation of nucleic acid-templated transcription
.actin crosslink formation
.negative regulation of cellular component movement
  + 8 more...
.ion channel binding
.ligand-dependent nuclear receptor transcription coactivator activity
.vinculin binding
  + 3 more...
.extracellular exosome
.dendritic spine
.cell projection
  + 14 more...
6 EBI-741724,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
7 EBI-741724,EBI-8639312 LMO1  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.zinc ion binding .nucleus
8 EBI-741724,EBI-358122 RPL9  
  .cellular protein metabolic process
.viral transcription
.viral life cycle
  + 8 more...
.rRNA binding
.structural constituent of ribosome
.RNA binding
.cytosolic large ribosomal subunit
.membrane
.focal adhesion
  + 5 more...
9 EBI-741724,EBI-359793 TXLNA  
  .activation of mitophagy in response to mitochondrial depolarization
.B cell activation
.cell proliferation
.exocytosis
.high molecular weight B cell growth factor receptor binding
.cytokine activity
.membrane
.cytoplasm
.extracellular region
10 EBI-741724,EBI-744248 MLH1  
  .meiotic spindle midzone assembly
.oogenesis
.negative regulation of mitotic recombination
  + 12 more...
.guanine/thymine mispair binding
.ATPase activity
.ATP binding
.MutLalpha complex
.membrane
.chiasma
  + 4 more...
11 EBI-741724,EBI-3905829 CCNG1  
  .cell division
.negative regulation of apoptotic process
.cell growth
  + 6 more...
.N/A .perinuclear region of cytoplasm
.neuronal cell body
.dendrite
.nucleus
12 EBI-741724,EBI-456371 CKS1B  
  .cell division
.cell proliferation
.mitotic cell cycle
  + 2 more...
.cyclin-dependent protein serine/threonine kinase regulator activity .nucleoplasm
13 EBI-741724,EBI-10224192 RUNX1T1  
  .negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.generation of precursor metabolites and energy
.metal ion binding
.identical protein binding
.transcription corepressor activity
  + 2 more...
.nuclear matrix
.mitochondrion
.cytoplasm
.nucleoplasm
14 EBI-741724,EBI-714158 PIN1  
  .negative regulation of cell motility
.negative regulation of ERK1 and ERK2 cascade
.regulation of pathway-restricted SMAD protein phosphorylation
  + 11 more...
.phosphothreonine binding
.phosphoserine binding
.GTPase activating protein binding
  + 2 more...
.midbody
.nuclear speck
.cytoplasm
  + 2 more...
15 EBI-741724,EBI-742350 TCEB3  
  .positive regulation of viral transcription
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.viral process
  + 4 more...
.DNA binding .elongin complex
.integral component of membrane
.cytoplasm
  + 3 more...
16 EBI-741724,EBI-10217913 RTP5  
  .N/A .N/A .integral component of membrane
17 EBI-741724,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
18 EBI-741724,EBI-10241513 PLEKHN1  
  .N/A .N/A .plasma membrane
19 EBI-741724,EBI-740767 ZC2HC1C  
  .N/A .metal ion binding .N/A
20 EBI-741724,EBI-2557469 PPP1R18  
  .N/A .N/A .cytoskeleton
.cytoplasm
21 EBI-741724,EBI-1643885 KLC3  
  .axon cargo transport .microtubule motor activity .neuron projection
.ciliary rootlet
.motile cilium
  + 3 more...
22 EBI-741724,EBI-10256685 PID1  
  .negative regulation of glucose import in response to insulin stimulus
.positive regulation of ATP biosynthetic process
.negative regulation of ATP biosynthetic process
  + 19 more...
.N/A .cytoplasm
.nucleoplasm
23 EBI-741724,EBI-10247802 CCDC146  
  .N/A .N/A .centriole
24 EBI-741724,EBI-742397 TEX11  
  .chiasma assembly
.negative regulation of apoptotic process
.fertilization
  + 6 more...
.N/A .central element
25 EBI-741724,EBI-10181988 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
26 EBI-741724,EBI-10264440 DZIP1L  
  .cilium assembly .metal ion binding .ciliary basal body
27 EBI-741724,EBI-6872807 SYCE1  
  .cell division
.synaptonemal complex assembly
.N/A .central element
28 EBI-741724,EBI-625509 ZNF655  
  .negative regulation of G1/S transition of mitotic cell cycle
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
29 EBI-741724,EBI-954696 TCEANC  
  .regulation of DNA-templated transcription, elongation
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.DNA binding .nucleus
30 EBI-741724,EBI-10268729 GOLGA6L2  
  .N/A .N/A .N/A
31 EBI-741724,EBI-741032 CNNM3  
  .ion transport .N/A .integral component of membrane
.membrane
.plasma membrane
32 EBI-741724,EBI-742259 LMO3  
  .positive regulation of glucocorticoid receptor signaling pathway
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of fat cell differentiation
  + 3 more...
.zinc ion binding .cytoplasm
33 EBI-741724,EBI-10273713 ZNF564  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
34 EBI-741724,EBI-10275150 ARHGEF40  
  .N/A .Rho guanyl-nucleotide exchange factor activity .cytoplasm
35 EBI-741724,EBI-726510 LENG1  
  .N/A .N/A .N/A
36 EBI-741724,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
37 EBI-741724,EBI-372775 CEP95  
  .N/A .N/A .centrosome
.cytoplasm
.spindle pole
38 EBI-741724,EBI-2682299 ZMAT2  
  .N/A .zinc ion binding
.DNA binding
.nucleus
39 EBI-741724,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
40 EBI-741724,EBI-748391 SCNM1  
  .RNA splicing
.mRNA processing
.metal ion binding
.enzyme binding
.nuclear speck
.nucleolus
.nucleus
41 EBI-741724,EBI-744794 TSGA10  
  .cell projection assembly
.spermatogenesis
.N/A .neuron projection
.nuclear membrane
.motile cilium
.cytoplasm
42 EBI-741724,EBI-744115 CEP44  
  .N/A .N/A .midbody
.centrosome
.cytoplasm
.spindle pole
43 EBI-741724,EBI-744099 ENKD1  
  .N/A .N/A .microtubule cytoskeleton
.cytoplasmic microtubule
44 EBI-741724,EBI-514199 MED28  
  .negative regulation of smooth muscle cell differentiation
.stem cell maintenance
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .cortical actin cytoskeleton
.mediator complex
.membrane
45 EBI-741724,EBI-742909 ARMC7  
  .N/A .N/A .cytoplasm
.nucleus
46 EBI-741724,EBI-7112211 C19orf44  
  .N/A .N/A .N/A
47 EBI-741724,EBI-749353 METTL17  
  .translation .methyltransferase activity
.copper ion binding
.ribosome
.mitochondrion
.nucleoplasm
.nucleus
48 EBI-741724,EBI-8643161 C1orf109  
  .N/A .N/A .N/A
49 EBI-741724,EBI-743375 CHCHD3  
  .mitochondrial fusion
.inner mitochondrial membrane organization
.negative regulation of transcription from RNA polymerase II promoter
.protein complex scaffold
.phosphatase binding
.RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
.extracellular exosome
.mitochondrial inner membrane
.mitochondrion
  + 2 more...
50 EBI-741724,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
51 EBI-741724,EBI-514206 CTNNAL1  
  .Rho protein signal transduction
.cell adhesion
.N/A .plasma membrane
.cytoskeleton
.cytosol
52 EBI-741724,EBI-396137 CDC23  
  .protein K11-linked ubiquitination
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
.positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
  + 11 more...
.ubiquitin-protein transferase activity .cytosol
.anaphase-promoting complex
.nucleoplasm
.intracellular
53 EBI-741724,EBI-741528 CHIC2  
  .Golgi to plasma membrane transport .N/A .plasma membrane
.Golgi-associated vesicle
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
testis204
Health State
TissuesTPM*
normal8
germ cell tumor3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis31.5
Tissues
TissuesExpression level
testisLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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