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> Protein (NX_Q8NBT2)
Protein (NX_Q8NBT2)
Protein
Gene SymbolSPC24 to neXtProt (NX_Q8NBT2)
DescriptionKinetochore protein Spc24
Chromosome19
Location19p13.2 (11242196 ~ 11266484) to Ensembl
Sequene Features : Isoforms 2, Variants 14, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.small GTPase mediated signal transduction
.mitotic nuclear division
.mitotic cell cycle
.N/A .Ndc80 complex
.cytosol
.nucleolus
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 14 5
2014-09-19protein level
2 12 5
2014-05-27protein level
2 12 5
2014-02-25protein level
1 12 5
2013-12-09protein level
1 6 5
2013-11-01protein level
1 6 5
2013-09-12protein level
1 6 5
2013-08-17protein level
1 6 5
2013-07-15protein level
1 5 1
2013-06-11protein level
1 5 1
2013-02-12protein level
1 3 2
2012-12-20protein level
1 4 2
2012-10-30protein level
1 4 2
2012-10-07protein level
1 4 2
2012-08-24protein level
1 2 2
2012-07-28protein level
1 2 2
2012-06-08protein level
1 3 2
2012-05-07protein level
1 2 2
2012-04-10protein level
1 2 2
2012-01-13protein level
1 1 2
2011-12-20protein level
1 1 2
2011-11-11protein level
1 1 2
2011-08-23protein level
1 1 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NBT2-1
3 7 0 22464.3604
NX_Q8NBT2-2
0 7 0 17304.7489
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-999900,EBI-999909 SPC25  
  .cell division
.small GTPase mediated signal transduction
.mitotic nuclear division
  + 3 more...
.N/A .Ndc80 complex
.cytosol
.nucleus
.condensed chromosome kinetochore
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood8
bone27
brain3
cervix41
connective tissue6
embryonic tissue4
eye9
intestine17
kidney14
liver19
lung8
lymph135
ovary49
pancreas4
prostate10
skin4
stomach10
testis2
thymus50
Health State
TissuesTPM*
normal3
cervical tumor57
chondrosarcoma24
colorectal tumor26
gastrointestinal tumor16
germ cell tumor11
glioma27
kidney tumor29
leukemia21
liver tumor20
lung tumor19
lymphoma83
ovarian tumor52
pancreatic tumor9
primitive neuroectodermal tumor of the CNS23
prostate cancer19
retinoblastoma43
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult6
embryoid body14
neonate32
fetus5
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1
appendix3.7
bone marrow10.4
colon3.3
duodenum2.7
esophagus1.5
lymph node4.6
placenta2.8
skin1.7
small intestine2.4
spleen1.5
stomach2.6
testis3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609394, gene) Spindle pole body component 24, s. cerevisiae, homolog of; SPBC24OMIM


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