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> Protein (NX_Q8NDH3)
Protein (NX_Q8NDH3)
Protein
Gene SymbolNPEPL1 to neXtProt (NX_Q8NDH3)
DescriptionProbable aminopeptidase NPEPL1
Chromosome20
Location20q13.32 (57264187 ~ 57294294) to Ensembl
Sequene Features : Isoforms 5, Variants 52, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .manganese ion binding
.metalloexopeptidase activity
.aminopeptidase activity
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 52 0
2014-09-19protein level
5 38 0
2014-05-27protein level
5 38 0
2014-02-25protein level
5 38 0
2013-12-09protein level
5 26 0
2013-11-01protein level
5 26 0
2013-09-12protein level
5 26 0
2013-08-17protein level
5 26 0
2013-07-15protein level
5 14 0
2013-06-11protein level
5 14 0
2013-02-12protein level
5 5 0
2012-12-20protein level
5 8 0
2012-10-30protein level
3 10 0
2012-10-07protein level
3 10 0
2012-08-24protein level
3 10 0
2012-07-28protein level
3 10 0
2012-06-08protein level
3 5 0
2012-05-07protein level
3 5 0
2012-04-10protein level
3 5 0
2012-01-13protein level
3 5 0
2011-12-20protein level
3 9 0
2011-11-11protein level
3 9 0
2011-08-23protein level
3 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NDH3-1
0 22 0 55825.3074
NX_Q8NDH3-2
1 16 0 44097.6929
NX_Q8NDH3-3
3 14 0 42108.6294
NX_Q8NDH3-4
2 20 0 52637.4789
NX_Q8NDH3-5
1 20 0 50498.4781
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10269715,EBI-717422 TFCP2  
  .regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.sequence-specific DNA binding
.protein C-terminus binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites50
bladder100
blood32
bone69
brain24
cervix185
embryonic tissue61
esophagus49
eye76
heart33
intestine17
kidney23
liver4
lung32
lymph node22
mammary gland33
mouth45
muscle18
ovary98
pancreas32
parathyroid97
pituitary gland60
placenta35
prostate58
salivary gland197
skin23
spleen18
stomach31
testis34
thymus25
thyroid42
uterus34
vascular19
Health State
TissuesTPM*
normal33
bladder carcinoma113
breast (mammary gland) tumor53
cervical tumor144
colorectal tumor17
esophageal tumor57
gastrointestinal tumor42
germ cell tumor3
glioma9
head and neck tumor44
kidney tumor29
leukemia42
liver tumor10
lung tumor19
lymphoma27
non-neoplasia20
ovarian tumor105
pancreatic tumor47
prostate cancer38
soft tissue/muscle tissue tumor31
uterine tumor11
Developmental Stage
TissuesTPM*
adult37
embryoid body14
blastocyst81
fetus25
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue24.9
adrenal gland20.1
appendix17.8
bone marrow23.6
cerebral cortex11
colon12.5
duodenum22
esophagus23.8
gallbladder27.5
heart muscle22.3
kidney23.6
liver6.4
lung27.7
lymph node22
ovary19.2
pancreas12.6
placenta15.4
prostate21.1
salivary gland25.7
skin28.8
small intestine17.4
spleen33.5
stomach20.9
testis24.7
thyroid gland20.7
urinary bladder24.5
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumLow
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisLow
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
hippocampusLow
kidneyHigh
lateral ventricleLow
liverLow
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasLow
parathyroid glandMedium
placentaMedium
prostateLow
rectumMedium
salivary glandMedium
seminal vesicleLow
skeletal muscleMedium
skin 1Medium
skin 2Low
small intestineMedium
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandLow
tonsilLow
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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