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> Protein (NX_Q8NE31)
Protein (NX_Q8NE31)
Protein
Gene SymbolFAM13C to neXtProt (NX_Q8NE31)
DescriptionProtein FAM13C
Chromosome10
Location10q21.1 (61005890 ~ 61122939) to Ensembl
Sequene Features : Isoforms 5, Variants 126, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 126 2
2014-09-19protein level
5 88 2
2014-05-27transcript level
5 88 2
2014-02-25transcript level
5 88 2
2013-12-09transcript level
5 81 2
2013-11-01transcript level
5 70 2
2013-09-12transcript level
5 70 2
2013-08-17transcript level
5 70 2
2013-07-15transcript level
5 53 2
2013-06-11transcript level
5 53 2
2013-02-12transcript level
4 30 8
2012-12-20transcript level
4 27 8
2012-10-30transcript level
4 32 8
2012-10-07transcript level
4 32 2
2012-08-24transcript level
3 20 2
2012-07-28transcript level
3 20 2
2012-06-08transcript level
3 20 2
2012-05-07transcript level
3 20 2
2012-04-10transcript level
3 20 2
2012-01-13transcript level
3 3 2
2011-12-20transcript level
3 3 2
2011-11-11transcript level
3 3 2
2011-08-23transcript level
3 3 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NE31-1
0 22 1 65686.4348
NX_Q8NE31-2
1 18 0 50903.7884
NX_Q8NE31-3
0 16 1 54973.0252
NX_Q8NE31-4
0 20 1 56441.3839
NX_Q8NE31-5
1 19 1 56313.3257
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751248,EBI-2692369 KIF2A  
  .mitotic spindle assembly
.cell division
.cell differentiation
  + 9 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.motor activity
.sperm principal piece
.membrane
.microtubule
  + 4 more...
2 EBI-751248,EBI-2548868 CCDC172  
  .N/A .N/A .N/A
3 EBI-751248,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
4 EBI-751248,EBI-2549423 HMBOX1  
  .positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .cytoplasm
.nucleoplasm
.nucleus
5 EBI-751248,EBI-713786 PHC2  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 2 more...
.identical protein binding
.zinc ion binding
.DNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 2 more...
6 EBI-751248,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
7 EBI-751248,EBI-739789 DVL3  
  .positive regulation of canonical Wnt signaling pathway
.planar cell polarity pathway involved in neural tube closure
.cochlea morphogenesis
  + 12 more...
.protein heterodimerization activity
.beta-catenin binding
.frizzled binding
  + 2 more...
.cytosol
8 EBI-751248,EBI-742426 SDCBP2  
  .intracellular transport
.intracellular signal transduction
.nervous system development
.protein heterodimerization activity
.protein homodimerization activity
.protein C-terminus binding
.extracellular exosome
.plasma membrane
.cytoplasm
9 EBI-751248,EBI-394607 MED4  
  .positive regulation of transcription, DNA-templated
.androgen receptor signaling pathway
.intracellular steroid hormone receptor signaling pathway
  + 3 more...
.thyroid hormone receptor binding
.vitamin D receptor binding
.ligand-dependent nuclear receptor transcription coactivator activity
  + 3 more...
.mediator complex
.membrane
.nucleoplasm
.nucleus
10 EBI-751248,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
brain55
ear62
embryonic tissue18
eye86
intestine4
kidney14
liver4
lung2
muscle47
nerve257
pancreas32
placenta28
prostate5
stomach10
testis29
thymus12
uterus4
vascular19
Health State
TissuesTPM*
normal37
gastrointestinal tumor8
germ cell tumor7
glioma46
non-neoplasia20
pancreatic tumor9
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult22
embryoid body14
blastocyst16
fetus26
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12
adrenal gland18.7
appendix5.5
cerebral cortex26.1
colon6.2
duodenum5
esophagus17
gallbladder18.5
heart muscle7.7
kidney4.2
liver1.2
lung11.7
lymph node5.6
ovary22.8
pancreas2
placenta2.2
prostate22.1
salivary gland3.8
skin6.9
small intestine5.1
spleen5.4
stomach4
testis6.9
thyroid gland6.9
urinary bladder10.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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