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> Protein (NX_Q8NEG7)
Protein (NX_Q8NEG7)
Protein
Gene SymbolDENND6B to neXtProt (NX_Q8NEG7)
DescriptionProtein DENND6B
Chromosome22
Location22q13.33 (50747459 ~ 50765489) to Ensembl
Sequene Features : Isoforms 1, Variants 19, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of GTPase activity .Rab guanyl-nucleotide exchange factor activity .recycling endosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 19 0
2014-09-19transcript level
1 34 0
2014-05-27transcript level
1 34 0
2014-02-25transcript level
1 32 0
2013-12-09transcript level
1 16 0
2013-11-01transcript level
1 16 0
2013-09-12transcript level
1 16 0
2013-08-17transcript level
1 16 0
2013-07-15transcript level
1 10 0
2013-06-11transcript level
1 10 0
2013-02-12transcript level
1 3 0
2012-12-20transcript level
1 3 0
2012-10-30transcript level
1 4 0
2012-10-07transcript level
1 4 0
2012-08-24transcript level
1 3 0
2012-07-28transcript level
1 3 0
2012-06-08transcript level
1 3 0
2012-05-07transcript level
1 3 0
2012-04-10transcript level
1 3 0
2012-01-13transcript level
1 2 0
2011-12-20transcript level
1 2 0
2011-11-11transcript level
1 2 0
2011-08-23transcript level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NEG7-1
26 0 0 66421.5252
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
blood8
brain35
cervix41
embryonic tissue4
eye28
intestine4
kidney23
liver4
lung14
lymph node33
mammary gland6
nerve64
ovary29
pancreas32
prostate10
spleen18
stomach20
testis52
thymus12
tonsil58
uterus21
Health State
TissuesTPM*
normal26
cervical tumor57
germ cell tumor11
glioma27
kidney tumor29
liver tumor10
lymphoma96
ovarian tumor26
pancreatic tumor9
primitive neuroectodermal tumor of the CNS7
uterine tumor33
Developmental Stage
TissuesTPM*
adult19
blastocyst16
fetus26
infant85
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.4
adrenal gland6.5
appendix5.4
bone marrow1.3
cerebral cortex10.8
colon2.5
duodenum2.1
esophagus3.5
gallbladder6.7
heart muscle2
kidney6.5
lung9
lymph node6.3
ovary4.1
pancreas3.4
placenta1.9
prostate6.6
salivary gland3.8
skin3.5
small intestine2.8
spleen5.2
stomach6
testis10.7
thyroid gland6.3
urinary bladder4.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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