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> Protein (NX_Q8NEM7)
Protein (NX_Q8NEM7)
Protein
Gene SymbolSUPT20H to neXtProt (NX_Q8NEM7)
DescriptionTranscription factor SPT20 homolog
Chromosome13
Location13q13.3 (37583449 ~ 37633850) to Ensembl
Sequene Features : Isoforms 3, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
.gastrulation
.autophagy
.chromatin organization
.transcription cofactor activity .SAGA-type complex
.nucleolus
.SAGA complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 28 6
2014-09-19protein level
3 64 6
2014-05-27protein level
2 63 7
2014-02-25protein level
2 63 7
2013-12-09protein level
2 48 7
2013-11-01protein level
2 47 7
2013-09-12protein level
2 47 7
2013-08-17protein level
2 47 7
2013-07-15protein level
2 30 3
2013-06-11protein level
2 30 3
2013-02-12protein level
2 16 8
2012-12-20protein level
2 14 8
2012-10-30protein level
2 20 8
2012-10-07protein level
2 20 4
2012-08-24protein level
2 16 4
2012-07-28protein level
2 16 4
2012-06-08protein level
2 17 4
2012-05-07protein level
2 17 4
2012-04-10protein level
2 17 4
2012-01-13protein level
2 8 4
2011-12-20protein level
2 8 4
2011-11-11protein level
2 8 2
2011-08-23protein level
2 8 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NEM7-1
3 24 0 85734.8889
NX_Q8NEM7-2
0 25 0 80050.963
NX_Q8NEM7-3
2 24 0 87985.8555
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-946984,EBI-73946 MAPK14  
  .positive regulation of reactive oxygen species metabolic process
.positive regulation of myoblast fusion
.regulation of cytokine production involved in inflammatory response
  + 64 more...
.NFAT protein binding
.ATP binding
.MAP kinase kinase activity
  + 2 more...
.extracellular exosome
.cytosol
.mitochondrion
  + 4 more...
2 EBI-7568679,EBI-727146 ATG9A  
  .innate immune response
.late nucleophagy
.piecemeal microautophagy of nucleus
  + 5 more...
.N/A .recycling endosome
.late endosome membrane
.cytoplasmic vesicle
  + 8 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland151
ascites150
bladder33
blood57
bone41
bone marrow123
brain70
cervix41
connective tissue60
ear124
embryonic tissue122
esophagus49
eye71
heart33
intestine77
kidney90
larynx85
liver29
lung59
lymph180
lymph node100
mammary gland72
mouth136
muscle84
nerve64
ovary157
pancreas37
parathyroid48
pharynx49
pituitary gland121
placenta74
prostate47
salivary gland49
skin52
spleen149
stomach135
testis291
thymus138
thyroid42
trachea173
uterus90
vascular38
Health State
TissuesTPM*
normal93
adrenal tumor158
breast (mammary gland) tumor75
cervical tumor57
chondrosarcoma48
colorectal tumor71
esophageal tumor57
gastrointestinal tumor151
germ cell tumor144
glioma27
head and neck tumor104
kidney tumor87
leukemia95
liver tumor41
lung tumor29
lymphoma110
non-neoplasia62
ovarian tumor196
pancreatic tumor19
primitive neuroectodermal tumor of the CNS78
prostate cancer9
retinoblastoma64
skin tumor39
soft tissue/muscle tissue tumor47
uterine tumor122
Developmental Stage
TissuesTPM*
adult87
embryoid body128
blastocyst97
neonate64
fetus122
infant127
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue15.2
adrenal gland21.9
appendix28.8
bone marrow21.5
cerebral cortex17.1
colon20.6
duodenum20.4
esophagus19.7
gallbladder24.3
heart muscle17.9
kidney19.3
liver9.1
lung23.4
lymph node31.2
ovary34
pancreas10.2
placenta26.6
prostate26.3
salivary gland17.4
skin22.6
small intestine20.8
spleen28
stomach22.4
testis70.9
thyroid gland26.5
urinary bladder29.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613417, gene) Family with sequence similarity 48, member a; FAM48AOMIM


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