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> Protein (NX_Q8NF99)
Protein (NX_Q8NF99)
Protein
Gene SymbolZNF397 to neXtProt (NX_Q8NF99)
DescriptionZinc finger protein 397
Chromosome18
Location18q12.2 (32820994 ~ 32847097) to Ensembl
Sequene Features : Isoforms 3, Variants 50, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 50 1
2014-09-19protein level
3 40 1
2014-05-27protein level
3 40 2
2014-02-25protein level
3 39 2
2013-12-09protein level
3 30 2
2013-11-01protein level
3 28 1
2013-09-12protein level
3 28 1
2013-08-17protein level
3 28 1
2013-07-15protein level
3 18 0
2013-06-11protein level
3 18 0
2013-02-12protein level
3 9 3
2012-12-20protein level
3 12 3
2012-10-30protein level
3 13 3
2012-10-07protein level
3 13 1
2012-08-24protein level
3 12 1
2012-07-28protein level
3 12 1
2012-06-08protein level
3 0 1
2012-05-07protein level
3 0 1
2012-04-10protein level
3 0 1
2012-01-13protein level
3 0 1
2011-12-20protein level
3 0 1
2011-11-11protein level
3 0 1
2011-08-23protein level
3 0 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NF99-1
16 11 5 61099.7978
NX_Q8NF99-2
1 11 0 31032.4632
NX_Q8NF99-3
2 9 0 24125.1521
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10213894,EBI-1383852 PRKAA2  
  .regulation of energy homeostasis
.membrane organization
.fatty acid homeostasis
  + 31 more...
.[acetyl-CoA carboxylase] kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
.metal ion binding
  + 7 more...
.AMP-activated protein kinase complex
.cytosol
.cytoplasm
.nucleoplasm
2 EBI-10213894,EBI-2798728 LMO4  
  .regulation of cell activation
.thymus development
.positive regulation of transcription from RNA polymerase II promoter
  + 8 more...
.zinc ion binding
.transcription factor binding
.sequence-specific DNA binding transcription factor activity
.enhancer sequence-specific DNA binding
.transcription factor complex
3 EBI-10213894,EBI-720304 ZNF410  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood16
bone13
bone marrow41
brain27
cervix41
connective tissue6
embryonic tissue42
esophagus49
eye23
heart44
kidney18
liver29
lung8
lymph node66
mammary gland19
muscle28
nerve64
pancreas14
placenta49
prostate5
skin18
spleen56
stomach10
testis25
thymus62
thyroid21
trachea38
umbilical cord72
uterus21
Health State
TissuesTPM*
normal32
cervical tumor57
esophageal tumor57
germ cell tumor15
glioma27
head and neck tumor7
leukemia21
liver tumor52
lung tumor19
lymphoma27
non-neoplasia31
primitive neuroectodermal tumor of the CNS31
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult26
embryoid body28
blastocyst32
neonate32
fetus50
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.2
adrenal gland13.9
appendix18.7
bone marrow3.1
cerebral cortex14.8
colon12.8
duodenum11.5
esophagus10.4
gallbladder12
heart muscle7.6
kidney12.7
liver6.2
lung12.6
lymph node16.1
ovary17.9
pancreas4.7
placenta11.4
prostate14.9
salivary gland8.5
skin11.2
small intestine12.7
spleen16.4
stomach13.5
testis13
thyroid gland16.8
urinary bladder12.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609601, gene) Zinc finger protein 397; ZNF397OMIM


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