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> Protein (NX_Q8NHQ1)
Protein (NX_Q8NHQ1)
Protein
Gene SymbolCEP70 to neXtProt (NX_Q8NHQ1)
DescriptionCentrosomal protein of 70 kDa
Chromosome3
Location3q22.3 (138213186 ~ 138313380) to Ensembl
Sequene Features : Isoforms 5, Variants 85, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 85 4
2014-09-19protein level
5 65 4
2014-05-27protein level
5 65 4
2014-02-25protein level
5 65 4
2013-12-09protein level
5 50 4
2013-11-01protein level
5 48 4
2013-09-12protein level
5 48 4
2013-08-17protein level
5 48 4
2013-07-15protein level
5 34 0
2013-06-11protein level
5 34 0
2013-02-12protein level
5 24 0
2012-12-20protein level
5 22 0
2012-10-30protein level
5 26 0
2012-10-07protein level
5 26 0
2012-08-24protein level
5 18 0
2012-07-28protein level
5 18 0
2012-06-08protein level
5 25 0
2012-05-07protein level
5 25 0
2012-04-10protein level
5 25 0
2012-01-13protein level
5 16 0
2011-12-20protein level
3 13 0
2011-11-11protein level
3 13 0
2011-08-23protein level
3 13 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NHQ1-1
0 28 0 69707.7303
NX_Q8NHQ1-2
1 26 0 64839.177
NX_Q8NHQ1-3
0 8 0 25017.7161
NX_Q8NHQ1-4
0 27 0 67726.7631
NX_Q8NHQ1-5
1 26 0 67470.6104
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739624,EBI-618295 STK25  
  .Golgi reassembly
.establishment of Golgi localization
.Golgi localization
  + 12 more...
.metal ion binding
.protein homodimerization activity
.ATP binding
  + 2 more...
.extracellular exosome
.Golgi apparatus
.cytoplasm
2 EBI-739624,EBI-744471 ZBTB24  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.hematopoietic progenitor cell differentiation
.metal ion binding
.DNA binding
.nucleus
3 EBI-739624,EBI-1210440 ZSCAN12  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
4 EBI-739624,EBI-349968 SUV39H1  
  .cellular response to hypoxia
.rhythmic process
.negative regulation of transcription, DNA-templated
  + 15 more...
.protein N-terminus binding
.histone methyltransferase activity (H3-K9 specific)
.histone methyltransferase activity
  + 5 more...
.rDNA heterochromatin
.chromatin silencing complex
.nucleoplasm
  + 5 more...
5 EBI-739624,EBI-710124 KDM1A  
  .positive regulation of stem cell proliferation
.positive regulation of neural precursor cell proliferation
.negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
  + 27 more...
.androgen receptor binding
.flavin adenine dinucleotide binding
.transcription regulatory region DNA binding
  + 13 more...
.transcription factor complex
.nucleoplasm
.nucleus
.nuclear chromatin
6 EBI-739624,EBI-750559 SLU7  
  .cellular response to heat
.intracellular protein transport
.mRNA splicing, via spliceosome
  + 3 more...
.pre-mRNA 3'-splice site binding
.zinc ion binding
.second spliceosomal transesterification activity
.catalytic step 2 spliceosome
.intracellular membrane-bounded organelle
.small nuclear ribonucleoprotein complex
  + 6 more...
7 EBI-739624,EBI-352528 HSPD1  
  .protein maturation
.chaperone-mediated protein complex assembly
.positive regulation of T cell activation
  + 21 more...
.chaperone binding
.unfolded protein binding
.poly(A) RNA binding
  + 8 more...
.extracellular exosome
.lipopolysaccharide receptor complex
.protein complex
  + 13 more...
8 EBI-739624,EBI-1183307 ERCC3  
  .regulation of mitotic cell cycle phase transition
.positive regulation of viral transcription
.positive regulation of transcription from RNA polymerase II promoter
  + 27 more...
.protein N-terminus binding
.3'-5' DNA helicase activity
.peptide binding
  + 10 more...
.holo TFIIH complex
.nucleoplasm
.nucleus
.core TFIIH complex
9 EBI-739624,EBI-359352 PSMA1  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.RNA binding
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.polysome
  + 7 more...
10 EBI-739624,EBI-351257 DDX6  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.cytoplasmic mRNA processing body assembly
.viral RNA genome packaging
  + 4 more...
.poly(A) RNA binding
.protein domain specific binding
.ATP binding
  + 3 more...
.intracellular membrane-bounded organelle
.RISC complex
.membrane
  + 5 more...
11 EBI-739624,EBI-356849 RPL13  
  .cellular protein metabolic process
.viral transcription
.viral life cycle
  + 8 more...
.poly(A) RNA binding
.structural constituent of ribosome
.RNA binding
.cytosolic ribosome
.cytosolic large ribosomal subunit
.membrane
  + 4 more...
12 EBI-739624,EBI-945751 COIL  
  .N/A .identical protein binding
.protein C-terminus binding
.membrane
.Cajal body
.cytoplasm
  + 3 more...
13 EBI-739624,EBI-356811 NOP2  
  .positive regulation of cell proliferation
.rRNA processing
.poly(A) RNA binding
.S-adenosylmethionine-dependent methyltransferase activity
.nucleolus
14 EBI-739624,EBI-355815 ATP5O  
  .small molecule metabolic process
.cellular metabolic process
.mitochondrial ATP synthesis coupled proton transport
  + 3 more...
.proton-transporting ATP synthase activity, rotational mechanism
.transmembrane transporter activity
.drug binding
.transporter activity
.extracellular exosome
.plasma membrane
.mitochondrial proton-transporting ATP synthase complex
  + 3 more...
15 EBI-739624,EBI-746484 NRIP1  
  .positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
.circadian regulation of gene expression
  + 6 more...
.androgen receptor binding
.glucocorticoid receptor binding
.nuclear hormone receptor binding
  + 4 more...
.cell junction
.nuclear speck
.nucleolus
  + 3 more...
16 EBI-739624,EBI-489887 EMD  
  .cellular response to growth factor stimulus
.regulation of canonical Wnt signaling pathway
.negative regulation of fibroblast proliferation
  + 8 more...
.beta-tubulin binding
.actin binding
.nuclear membrane
.integral component of membrane
.membrane
  + 5 more...
17 EBI-739624,EBI-749129 ZNF136  
  .transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription corepressor activity
.DNA binding
.nucleus
18 EBI-739624,EBI-4319440 EMP1  
  .bleb assembly
.cell growth
.epidermis development
  + 3 more...
.N/A .integral component of membrane
.membrane
.plasma membrane
19 EBI-739624,EBI-1048159 MFAP1  
  .extracellular matrix organization .poly(A) RNA binding .extracellular region
.microfibril
20 EBI-739624,EBI-297993 SNRPD2  
  .ncRNA metabolic process
.gene expression
.RNA splicing
  + 3 more...
.poly(A) RNA binding .catalytic step 2 spliceosome
.extracellular exosome
.SMN-Sm protein complex
  + 9 more...
21 EBI-739624,EBI-1042725 AKAP17A  
  .regulation of RNA splicing
.B cell activation
.RNA splicing
  + 3 more...
.protein kinase A binding
.poly(A) RNA binding
.nucleotide binding
.nuclear speck
.cytoplasm
.spliceosomal complex
  + 2 more...
22 EBI-739624,EBI-713456 IK  
  .cell-cell signaling
.immune response
.identical protein binding .nucleolus
.nucleoplasm
.extracellular space
23 EBI-739624,EBI-396072 PPIG  
  .RNA splicing
.protein folding
.protein peptidyl-prolyl isomerization
.poly(A) RNA binding
.cyclosporin A binding
.peptidyl-prolyl cis-trans isomerase activity
.nuclear speck
.nuclear matrix
.cytoplasm
  + 2 more...
24 EBI-739624,EBI-358049 BYSL  
  .cell proliferation
.female pregnancy
.cell adhesion
  + 2 more...
.poly(A) RNA binding .apical part of cell
.intracellular membrane-bounded organelle
.membrane
  + 3 more...
25 EBI-739624,EBI-702370 TRIM29  
  .negative regulation of protein localization to nucleus
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.intermediate filament cytoskeleton
.cytoplasm
.nucleoplasm
26 EBI-739624,EBI-742350 TCEB3  
  .positive regulation of viral transcription
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.viral process
  + 4 more...
.DNA binding .elongin complex
.integral component of membrane
.cytoplasm
  + 3 more...
27 EBI-739624,EBI-7115319 ZNF266  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
28 EBI-739624,EBI-10234472 ZNF169  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
29 EBI-739624,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
30 EBI-739624,EBI-8787052 ZNF239  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.RNA binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
31 EBI-739624,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
32 EBI-739624,EBI-10241197 TSGA10IP  
  .N/A .N/A .N/A
33 EBI-739624,EBI-2372076 GPATCH4  
  .N/A .poly(A) RNA binding .N/A
34 EBI-739624,EBI-2556193 KANK2  
  .negative regulation of G1/S transition of mitotic cell cycle
.negative regulation of vitamin D receptor signaling pathway
.negative regulation of programmed cell death
  + 5 more...
.N/A .mitochondrion
.cytoplasm
35 EBI-739624,EBI-747711 DIEXF  
  .multicellular organismal development
.maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
.poly(A) RNA binding
.U3 snoRNA binding
.rRNA binding
.small-subunit processome
.nucleolus
36 EBI-739624,EBI-930143 CDC73  
  .negative regulation of G1/S transition of mitotic cell cycle
.cellular response to lipopolysaccharide
.negative regulation of epithelial cell proliferation
  + 17 more...
.RNA polymerase II core binding .Cdc73/Paf1 complex
.nucleoplasm
.nucleus
37 EBI-739624,EBI-3920396 C11orf57  
  .N/A .N/A .N/A
38 EBI-739624,EBI-7844656 TTLL10  
  .cellular protein modification process .N/A .N/A
39 EBI-739624,EBI-745689 FAM214B  
  .N/A .N/A .nucleus
40 EBI-739624,EBI-10257016 ZNF572  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
41 EBI-739624,EBI-7233259 ZNF329  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
42 EBI-739624,EBI-744506 FAM124A  
  .N/A .N/A .N/A
43 EBI-739624,EBI-720304 ZNF410  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
44 EBI-739624,EBI-2799529 ZNF227  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
45 EBI-739624,EBI-1104535 SFR1  
  .double-strand break repair via homologous recombination .N/A .Swi5-Sfr1 complex
.nucleus
46 EBI-739624,EBI-1104570 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
47 EBI-739624,EBI-3439227 ZGPAT  
  .negative regulation of transcription, DNA-templated
.negative regulation of epidermal growth factor-activated receptor activity
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.nucleus
48 EBI-739624,EBI-2813661 ZNF366  
  .response to estrogen
.negative regulation of intracellular estrogen receptor signaling pathway
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.estrogen receptor binding
.transcription corepressor activity
.DNA binding
.nucleus
49 EBI-739624,EBI-10268158 FAM133A  
  .N/A .N/A .N/A
50 EBI-739624,EBI-747580 ZNF439  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
51 EBI-739624,EBI-751248 FAM13C  
  .N/A .N/A .N/A
52 EBI-739624,EBI-10270752 ZNF555  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
53 EBI-739624,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
54 EBI-739624,EBI-597063 ZCCHC10  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
55 EBI-739624,EBI-2939487 SYTL5  
  .calcium ion-dependent exocytosis of neurotransmitter
.regulation of calcium ion-dependent exocytosis
.synaptic vesicle exocytosis
  + 2 more...
.clathrin binding
.syntaxin binding
.calcium-dependent phospholipid binding
.calcium ion binding
.exocytic vesicle
.plasma membrane
56 EBI-739624,EBI-10277297 HMGB4  
  .regulation of transcription, DNA-templated
.chromatin remodeling
.chromatin binding
.DNA binding
.chromosome
.nucleus
57 EBI-739624,EBI-923440 GATAD2B  
  .ATP-dependent chromatin remodeling
.transcription, DNA-templated
.sequence-specific DNA binding
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.protein complex
.nuclear speck
.nucleoplasm
.nuclear chromatin
58 EBI-739624,EBI-455078 SMARCE1  
  .negative regulation of transcription, DNA-templated
.ATP-dependent chromatin remodeling
.metabolic process
  + 4 more...
.protein N-terminus binding
.ligand-dependent nuclear receptor binding
.N-acetyltransferase activity
  + 4 more...
.nBAF complex
.npBAF complex
.protein complex
  + 6 more...
59 EBI-739624,EBI-726510 LENG1  
  .N/A .N/A .N/A
60 EBI-739624,EBI-747142 SYTL4  
  .multivesicular body sorting pathway
.positive regulation of protein secretion
.calcium ion-dependent exocytosis of neurotransmitter
  + 6 more...
.neurexin family protein binding
.clathrin binding
.syntaxin binding
  + 4 more...
.exocytic vesicle
.transport vesicle membrane
.secretory granule
  + 6 more...
61 EBI-739624,EBI-746252 GCC1  
  .protein targeting to Golgi .N/A .plasma membrane
.Golgi apparatus
.cytoplasm
.Golgi membrane
62 EBI-739624,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
63 EBI-739624,EBI-5278764 CDCA7L  
  .positive regulation of cell proliferation
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .cytoplasm
.nucleolus
.nucleus
64 EBI-739624,EBI-748884 LIN37  
  .regulation of cell cycle
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .transcriptional repressor complex
.nucleoplasm
65 EBI-739624,EBI-742422 CFAP53  
  .N/A .N/A .cilium
66 EBI-739624,EBI-1046387 TTC25  
  .N/A .N/A .cytoplasm
67 EBI-739624,EBI-739546 LENG8  
  .N/A .N/A .N/A
68 EBI-739624,EBI-749411 GPX7  
  .response to reactive oxygen species .glutathione peroxidase activity
.peroxidase activity
.catalase activity
.endoplasmic reticulum lumen
.endoplasmic reticulum
.extracellular region
69 EBI-739624,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
70 EBI-739624,EBI-10293968 PPP1R16B  
  .positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
.negative regulation of peptidyl-serine dephosphorylation
.establishment of endothelial barrier
  + 6 more...
.protein phosphatase type 1 regulator activity .perinuclear region of cytoplasm
.cell projection
.plasma membrane
.nucleus
71 EBI-739624,EBI-473181 BARD1  
  .protein K6-linked ubiquitination
.negative regulation of protein export from nucleus
.positive regulation of protein catabolic process
  + 9 more...
.protein heterodimerization activity
.protein homodimerization activity
.kinase binding
  + 4 more...
.BRCA1-A complex
.intracellular membrane-bounded organelle
.BRCA1-BARD1 complex
  + 5 more...
72 EBI-739624,EBI-10295431 SSX3  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.nucleic acid binding .nucleus
73 EBI-739624,EBI-2568609 FAM64A  
  .cell division
.mitotic nuclear division
.N/A .cytoplasm
.nucleolus
.nucleus
74 EBI-739624,EBI-745392 SYT17  
  .positive regulation of dendrite extension
.calcium ion-dependent exocytosis of neurotransmitter
.regulation of calcium ion-dependent exocytosis
  + 2 more...
.clathrin binding
.syntaxin binding
.calcium-dependent phospholipid binding
.calcium ion binding
.plasma membrane
.trans-Golgi network
75 EBI-739624,EBI-10300345 CCDC94  
  .N/A .N/A .N/A
76 EBI-739624,EBI-2555618 NUSAP1  
  .positive regulation of mitotic nuclear division
.establishment of mitotic spindle localization
.mitotic chromosome condensation
  + 2 more...
.poly(A) RNA binding
.DNA binding
.spindle microtubule
.cytoplasm
.nucleolus
  + 2 more...
77 EBI-739624,EBI-745073 BEX2  
  .regulation of cell cycle
.regulation of apoptotic process
.cell cycle
.apoptotic process
.N/A .cytoplasm
.nucleus
78 EBI-739624,EBI-10303449 SETD5  
  .N/A .N/A .N/A
79 EBI-739624,EBI-2107221 CLPB  
  .cellular response to heat .ATP binding .mitochondrion
80 EBI-739624,EBI-744099 ENKD1  
  .N/A .N/A .microtubule cytoskeleton
.cytoplasmic microtubule
81 EBI-739624,EBI-751319 CARD9  
  .nucleotide-binding oligomerization domain containing signaling pathway
.defense response to virus
.defense response to Gram-positive bacterium
  + 17 more...
.CARD domain binding
.protein homodimerization activity
.plasma membrane
.cytosol
.cytoplasm
82 EBI-739624,EBI-716128 TAF1D  
  .negative regulation of gene expression, epigenetic
.regulation of gene expression, epigenetic
.gene expression
  + 5 more...
.DNA binding .microtubule organizing center
.RNA polymerase transcription factor SL1 complex
.nucleoplasm
83 EBI-739624,EBI-10308083 SH2D4A  
  .negative regulation of phosphatase activity .phosphatase binding .cytoplasm
84 EBI-739624,EBI-715389 C8orf33  
  .N/A .N/A .N/A
85 EBI-739624,EBI-749353 METTL17  
  .translation .methyltransferase activity
.copper ion binding
.ribosome
.mitochondrion
.nucleoplasm
.nucleus
86 EBI-739624,EBI-744488 PRKRIP1  
  .negative regulation of phosphorylation
.negative regulation of protein kinase activity
.renal system process
.protein kinase binding
.protein kinase inhibitor activity
.double-stranded RNA binding
.extracellular exosome
.nucleolus
87 EBI-739624,EBI-347633 ZNF408  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.identical protein binding
.DNA binding
.nucleus
88 EBI-739624,EBI-714781 BRMS1  
  .positive regulation of anoikis
.positive regulation of protein deacetylation
.negative regulation of transcription, DNA-templated
  + 6 more...
.NF-kappaB binding
.histone deacetylase binding
.Sin3-type complex
.cytoplasm
.nucleoplasm
.nucleus
89 EBI-739624,EBI-3916142 ZNF302  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
90 EBI-739624,EBI-10312733 ARHGEF3  
  .apoptotic signaling pathway
.regulation of small GTPase mediated signal transduction
.neurotrophin TRK receptor signaling pathway
  + 4 more...
.Rho guanyl-nucleotide exchange factor activity .cytosol
.intracellular
91 EBI-739624,EBI-5666657 GPATCH2L  
  .N/A .N/A .N/A
92 EBI-739624,EBI-716291 NIPSNAP3A  
  .N/A .N/A .cytosol
.nucleus
93 EBI-739624,EBI-716098 NOL12  
  .N/A .poly(A) RNA binding
.rRNA binding
.nucleolus
94 EBI-739624,EBI-1046350 DDX41  
  .defense response to virus
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 8 more...
.poly(A) RNA binding
.zinc ion binding
.ATP binding
  + 2 more...
.catalytic step 2 spliceosome
.membrane
.cytosol
  + 3 more...
95 EBI-739624,EBI-1105370 ZNF490  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
96 EBI-739624,EBI-2602396 ABT1  
  .small-subunit processome assembly
.spinal cord motor neuron differentiation
.transcription from RNA polymerase II promoter
  + 4 more...
.poly(A) RNA binding
.transcription coactivator activity
.DNA binding
.nucleotide binding
.nucleolus
.transcription factor complex
.nucleus
97 EBI-739624,EBI-2688184 ZNF148  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription, DNA-templated
.substantia nigra development
  + 6 more...
.metal ion binding
.sequence-specific DNA binding
.double-stranded DNA binding
  + 2 more...
.Golgi apparatus
.nucleoplasm
98 EBI-739624,EBI-2876697 UTP11L  
  .positive regulation of apoptotic process
.ribosomal small subunit biogenesis
.nervous system development
.rRNA processing
.poly(A) RNA binding .small-subunit processome
.cytoplasm
.nucleolus
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites75
bladder66
blood24
bone13
bone marrow41
brain39
cervix20
connective tissue6
embryonic tissue32
esophagus99
eye14
heart11
intestine38
kidney37
liver68
lung17
mammary gland92
mouth60
muscle28
parathyroid97
placenta17
prostate100
skin18
spleen18
stomach20
testis174
thymus125
thyroid21
uterus34
vascular19
Health State
TissuesTPM*
normal40
breast (mammary gland) tumor32
cervical tumor28
chondrosarcoma12
esophageal tumor115
gastrointestinal tumor59
germ cell tumor98
glioma18
head and neck tumor29
kidney tumor43
leukemia52
liver tumor41
lung tumor29
non-neoplasia10
primitive neuroectodermal tumor of the CNS55
prostate cancer38
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor66
Developmental Stage
TissuesTPM*
adult40
embryoid body28
neonate64
fetus34
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.8
adrenal gland10.5
appendix5.8
bone marrow3
cerebral cortex11.9
colon16.1
duodenum48.6
esophagus10.2
gallbladder11.8
heart muscle11.4
kidney16.5
liver14.3
lung10.7
lymph node4.2
ovary13.9
pancreas12.2
placenta3.3
prostate15.7
salivary gland5.3
skin3.4
small intestine16.7
spleen4.5
stomach9.9
testis66.7
thyroid gland31.2
urinary bladder11.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Low
epididymisMedium
esophagusLow
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusLow
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614310, gene) Centrosomal protein, 70-kd; CEP70OMIM


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