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> Protein (NX_Q8NI60)
Protein (NX_Q8NI60)
Protein
Gene SymbolADCK3 to neXtProt (NX_Q8NI60)
DescriptionChaperone activity of bc1 complex-like, mitochondrial
Chromosome1
Location1q42.13 (227085237 ~ 227175246) to Ensembl
Sequene Features : Isoforms 4, Variants 100, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.phosphorylation
.ubiquinone biosynthetic process
.ADP binding
.kinase activity
.ATP binding
.integral component of membrane
.mitochondrion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 100 7
2014-09-19protein level
4 83 7
2014-05-27protein level
4 83 7
2014-02-25protein level
4 82 7
2013-12-09protein level
4 51 7
2013-11-01protein level
4 50 1
2013-09-12protein level
4 50 1
2013-08-17protein level
4 50 1
2013-07-15protein level
4 35 1
2013-06-11protein level
4 35 1
2013-02-12protein level
4 24 3
2012-12-20protein level
4 21 3
2012-10-30protein level
4 26 3
2012-10-07protein level
4 26 1
2012-08-24protein level
4 25 1
2012-07-28protein level
4 25 1
2012-06-08protein level
4 26 1
2012-05-07protein level
4 24 1
2012-04-10protein level
4 24 1
2012-01-13protein level
4 14 1
2011-12-20protein level
4 14 1
2011-11-11protein level
4 14 1
2011-08-23protein level
4 14 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8NI60-1
3 24 0 71904.1899
NX_Q8NI60-2
1 8 0 18924.3552
NX_Q8NI60-3
0 24 0 66584.3183
NX_Q8NI60-4
1 16 0 42509.1674
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-745535,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
2 EBI-745535,EBI-9675724 TMEM239  
  .N/A .N/A .integral component of membrane
3 EBI-745535,EBI-7055862 TMEM159  
  .N/A .N/A .integral component of membrane
4 EBI-745535,EBI-750345 REEP6  
  .regulation of intracellular transport .N/A .apical part of cell
.rod spherule
.integral component of membrane
  + 2 more...
5 EBI-745535,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
6 EBI-745535,EBI-712367 RABAC1  
  .N/A .identical protein binding .cell junction
.integral component of membrane
.membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue388
adrenal gland273
ascites175
bladder33
blood49
bone13
bone marrow20
brain118
connective tissue67
embryonic tissue18
esophagus99
eye67
heart402
intestine146
kidney123
larynx42
liver53
lung80
lymph45
lymph node22
mammary gland59
mouth529
muscle291
nerve64
ovary147
pancreas60
parathyroid48
pharynx98
placenta14
prostate126
skin47
spleen149
stomach376
testis110
thymus326
thyroid107
trachea173
uterus68
vascular38
Health State
TissuesTPM*
normal107
breast (mammary gland) tumor53
chondrosarcoma36
colorectal tumor142
esophageal tumor115
gastrointestinal tumor329
germ cell tumor75
glioma65
head and neck tumor127
kidney tumor29
leukemia42
liver tumor72
lung tumor38
lymphoma27
non-neoplasia62
ovarian tumor170
primitive neuroectodermal tumor of the CNS94
prostate cancer57
retinoblastoma64
skin tumor39
soft tissue/muscle tissue tumor15
uterine tumor44
Developmental Stage
TissuesTPM*
adult86
embryoid body14
blastocyst32
neonate32
fetus61
infant85
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue67.5
adrenal gland69.6
appendix15.1
bone marrow27.5
cerebral cortex12.2
colon22.7
duodenum29.7
esophagus40.9
gallbladder31.5
heart muscle77.1
kidney31.3
liver28
lung18.7
lymph node19.9
ovary47
pancreas51.9
placenta11.4
prostate37
salivary gland27.5
skin24.6
small intestine21.1
spleen21.1
stomach36.7
testis14.8
thyroid gland10.3
urinary bladder17.7
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowLow
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
kidneyHigh
lateral ventricleLow
liverLow
lungHigh
lymph nodeHigh
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasHigh
parathyroid glandHigh
placentaMedium
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineHigh
soft tissue 1Medium
soft tissue 2Medium
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606980, gene) Aarf domain-containing kinase 3; ADCK3OMIM
2(#612016, phenotype) Coenzyme q10 deficiency, primary, 4; COQ10D4OMIM


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