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> Protein (NX_Q8TAI7)
Protein (NX_Q8TAI7)
Protein
Gene SymbolRHEBL1 to neXtProt (NX_Q8TAI7)
DescriptionGTPase RhebL1
Chromosome12
Location12q13.12 (49458468 ~ 49463808) to Ensembl
Sequene Features : Isoforms 2, Variants 18, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of NF-kappaB transcription factor activity
.TOR signaling
.small GTPase mediated signal transduction
.metal ion binding
.GTP binding
.membrane
.endomembrane system
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 18 3
2014-09-19protein level
2 11 3
2014-05-27protein level
2 9 3
2014-02-25protein level
2 9 3
2013-12-09protein level
2 8 3
2013-11-01protein level
2 8 3
2013-09-12protein level
2 8 3
2013-08-17protein level
2 8 3
2013-07-15protein level
2 7 2
2013-06-11protein level
2 7 2
2013-02-12protein level
2 2 2
2012-12-20protein level
2 2 2
2012-10-30protein level
2 2 2
2012-10-07protein level
2 2 2
2012-08-24protein level
2 1 2
2012-07-28protein level
2 1 2
2012-06-08protein level
2 6 2
2012-05-07protein level
2 6 2
2012-04-10protein level
2 6 2
2012-01-13protein level
2 6 2
2011-12-20protein level
2 6 2
2011-11-11protein level
2 6 2
2011-08-23protein level
2 6 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TAI7-1
7 0 0 20668.518
NX_Q8TAI7-2
2 0 0 8170.3431
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-746555,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
2 EBI-746555,EBI-741101 FHL3  
  .actin cytoskeleton organization
.muscle organ development
.zinc ion binding .Z disc
.focal adhesion
.nucleus
.stress fiber
3 EBI-746555,EBI-741243 APPL1  
  .extrinsic apoptotic signaling pathway in absence of ligand
.extrinsic apoptotic signaling pathway
.regulation of establishment of protein localization to plasma membrane
  + 7 more...
.protein kinase B binding
.identical protein binding
.extracellular exosome
.early endosome membrane
.vesicle membrane
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood24
brain4
embryonic tissue4
eye4
heart22
intestine8
liver4
lung2
lymph22
muscle9
placenta3
prostate5
uterus4
Health State
TissuesTPM*
normal3
bladder carcinoma113
gastrointestinal tumor8
glioma18
leukemia10
liver tumor10
lymphoma13
prostate cancer9
retinoblastoma21
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult3
embryoid body14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix1.6
bone marrow2.7
cerebral cortex2.4
lung1.4
lymph node3
skin2.1
spleen2.1
testis1.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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