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> Protein (NX_Q8TBB0)
Protein (NX_Q8TBB0)
Protein
Gene SymbolTHAP6 to neXtProt (NX_Q8TBB0)
DescriptionTHAP domain-containing protein 6
Chromosome4
Location4q21.1 (76439156 ~ 76475683) to Ensembl
Sequene Features : Isoforms 3, Variants 26, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .metal ion binding
.DNA binding
.microtubule cytoskeleton
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
3 26 0
2014-09-19transcript level
3 22 0
2014-05-27transcript level
3 22 0
2014-02-25transcript level
2 22 0
2013-12-09transcript level
2 15 0
2013-11-01transcript level
2 14 0
2013-09-12transcript level
2 14 0
2013-08-17transcript level
2 14 0
2013-07-15transcript level
2 8 0
2013-06-11transcript level
2 8 0
2013-02-12transcript level
2 5 0
2012-12-20transcript level
2 5 0
2012-10-30transcript level
2 9 0
2012-10-07transcript level
2 9 0
2012-08-24transcript level
2 9 0
2012-07-28transcript level
2 9 0
2012-06-08transcript level
2 9 0
2012-05-07transcript level
2 9 0
2012-04-10transcript level
2 9 0
2012-01-13transcript level
2 3 0
2011-12-20transcript level
2 3 0
2011-11-11transcript level
2 3 0
2011-08-23transcript level
2 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TBB0-1
1 7 0 25673.9951
NX_Q8TBB0-2
1 6 0 20814.5549
NX_Q8TBB0-3
2 4 0 18498.5595
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3925505,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder100
blood8
bone13
brain25
cervix41
connective tissue6
embryonic tissue14
eye4
intestine12
kidney42
liver38
lung17
mammary gland6
mouth60
muscle18
nerve64
pancreas28
pharynx24
placenta21
prostate26
salivary gland49
skin23
stomach31
testis52
thymus37
thyroid21
trachea19
uterus34
vascular19
Health State
TissuesTPM*
normal23
adrenal tumor79
bladder carcinoma113
breast (mammary gland) tumor10
cervical tumor57
colorectal tumor8
gastrointestinal tumor16
germ cell tumor7
glioma18
head and neck tumor29
kidney tumor29
liver tumor72
non-neoplasia10
pancreatic tumor9
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor22
Developmental Stage
TissuesTPM*
adult16
embryoid body14
blastocyst16
neonate32
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.2
adrenal gland9.2
appendix10.3
bone marrow4.1
cerebral cortex9.5
colon7.8
duodenum9
esophagus7.5
gallbladder7.8
heart muscle9.3
kidney8.5
liver6.4
lung7.9
lymph node11.4
ovary11.2
pancreas2.9
placenta8.3
prostate10.3
salivary gland6.9
skin8.7
small intestine9.6
spleen10
stomach7.6
testis18.2
thyroid gland12.9
urinary bladder9.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612535, gene) Thap domain-containing protein 6; THAP6OMIM


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