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> Protein (NX_Q8TBB1)
Protein (NX_Q8TBB1)
Protein
Gene SymbolLNX1 to neXtProt (NX_Q8TBB1)
DescriptionE3 ubiquitin-protein ligase LNX
Chromosome4
Location4q12 (54325468 ~ 54567572) to Ensembl
Sequene Features : Isoforms 2, Variants 130, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 130 2
2014-09-19protein level
2 99 2
2014-05-27protein level
2 99 2
2014-02-25protein level
2 99 2
2013-12-09protein level
2 70 2
2013-11-01protein level
2 66 2
2013-09-12protein level
2 66 2
2013-08-17protein level
2 66 2
2013-07-15protein level
2 51 2
2013-06-11protein level
2 51 2
2013-02-12protein level
2 28 0
2012-12-20protein level
2 26 0
2012-10-30protein level
2 33 0
2012-10-07protein level
2 33 0
2012-08-24protein level
2 23 0
2012-07-28protein level
2 23 0
2012-06-08protein level
2 27 0
2012-05-07protein level
2 27 0
2012-04-10protein level
2 27 0
2012-01-13protein level
2 14 0
2011-12-20protein level
2 14 0
2011-11-11protein level
2 14 0
2011-08-23protein level
2 14 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TBB1-1
5 29 1 80577.551
NX_Q8TBB1-2
1 29 1 69599.6091
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739832,EBI-726769 ZNF593  
  .activation of mitophagy in response to mitochondrial depolarization
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription corepressor activity
.DNA binding
.nucleolus
.nucleus
2 EBI-739832,EBI-713635 NCK2  
  .negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.ephrin receptor signaling pathway
.vascular endothelial growth factor receptor signaling pathway
  + 16 more...
.receptor signaling complex scaffold activity
.cytoskeletal adaptor activity
.SH3/SH2 adaptor activity
.vesicle membrane
.cytosol
.endoplasmic reticulum
.cytoplasm
3 EBI-739832,EBI-2515299 SSNA1  
  .ciliary receptor clustering involved in smoothened signaling pathway
.intraciliary transport
.organelle organization
  + 2 more...
.N/A .ciliary basal body
.cytosol
.centrosome
.nucleus
4 EBI-739832,EBI-748664 HSBP1  
  .regulation of cellular response to heat
.endodermal cell differentiation
.cellular response to heat
  + 2 more...
.transcription corepressor activity .cytoskeleton
.nucleoplasm
.nucleus
5 EBI-739832,EBI-7875264 DAB1  
  .lateral motor column neuron migration
.Golgi localization
.negative regulation of axonogenesis
  + 15 more...
.N/A .perinuclear region of cytoplasm
.apical part of cell
.neuronal cell body
  + 5 more...
6 EBI-739832,EBI-10188956 RFPL3  
  .N/A .zinc ion binding .N/A
7 EBI-739832,EBI-1055693 RAD51D  
  .strand invasion
.reciprocal meiotic recombination
.DNA repair
  + 2 more...
.gamma-tubulin binding
.DNA-dependent ATPase activity
.ATP binding
  + 2 more...
.Rad51B-Rad51C-Rad51D-XRCC2 complex
.centrosome
.cytoplasm
  + 3 more...
8 EBI-739832,EBI-536866 NUDT14  
  .N/A .ADP-ribose diphosphatase activity
.metal ion binding
.UDP-sugar diphosphatase activity
.extracellular exosome
.cytoplasm
9 EBI-739832,EBI-2952751 ALDOC  
  .canonical glycolysis
.protein heterotetramerization
.protein homotetramerization
  + 13 more...
.cytoskeletal protein binding
.fructose-bisphosphate aldolase activity
.extracellular exosome
.axon
.cytoskeleton
  + 2 more...
10 EBI-739832,EBI-8638511 RBMY1A1  
  .RNA splicing
.mRNA processing
.regulation of alternative mRNA splicing, via spliceosome
.mRNA binding
.nucleotide binding
.nucleus
11 EBI-739832,EBI-621482 SRC  
  .regulation of caveolin-mediated endocytosis
.negative regulation of intrinsic apoptotic signaling pathway
.negative regulation of extrinsic apoptotic signaling pathway
  + 100 more...
.scaffold protein binding
.growth factor receptor binding
.hormone receptor binding
  + 14 more...
.extracellular exosome
.perinuclear region of cytoplasm
.neuron projection
  + 13 more...
12 EBI-739832,EBI-750589 PBLD  
  .negative regulation of pathway-restricted SMAD protein phosphorylation
.negative regulation of SMAD protein import into nucleus
.negative regulation of epithelial cell proliferation
  + 5 more...
.isomerase activity .extracellular exosome
.cytoplasm
13 EBI-739832,EBI-946999 GDI1  
  .negative regulation of protein targeting to membrane
.response to calcium ion
.regulation of small GTPase mediated signal transduction
  + 5 more...
.GTPase activator activity
.Rab GDP-dissociation inhibitor activity
.GDP-dissociation inhibitor activity
.protein complex
.neuron projection
.midbody
  + 3 more...
14 EBI-739832,EBI-9250559 CDA  
  .nucleobase-containing small molecule metabolic process
.protein homotetramerization
.negative regulation of nucleotide metabolic process
  + 8 more...
.protein homodimerization activity
.zinc ion binding
.cytidine deaminase activity
.nucleoside binding
.cytosol
.extracellular region
15 EBI-739832,EBI-718700 CA8  
  .phosphatidylinositol-mediated signaling
.one-carbon metabolic process
.zinc ion binding
.carbonate dehydratase activity
.cytoplasm
16 EBI-739832,EBI-945751 COIL  
  .N/A .identical protein binding
.protein C-terminus binding
.membrane
.Cajal body
.cytoplasm
  + 3 more...
17 EBI-739832,EBI-713568 MAPK9  
  .positive regulation of apoptotic signaling pathway
.cellular response to growth factor stimulus
.cellular response to tumor necrosis factor
  + 45 more...
.cysteine-type endopeptidase activator activity involved in apoptotic process
.transcription factor binding
.ATP binding
.JUN kinase activity
.cytosol
.mitochondrion
.nucleoplasm
18 EBI-739832,EBI-750020 CLK2  
  .protein autophosphorylation
.negative regulation of gluconeogenesis
.regulation of RNA splicing
  + 3 more...
.ATP binding
.protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity
.nuclear speck
.nucleoplasm
.nucleus
19 EBI-739832,EBI-7410441 BLVRA  
  .oxidation-reduction process
.small molecule metabolic process
.heme catabolic process
.porphyrin-containing compound metabolic process
.zinc ion binding
.biliverdin reductase activity
.extracellular exosome
.cytosol
20 EBI-739832,EBI-740475 PCBD1  
  .protein heterooligomerization
.protein homotetramerization
.positive regulation of transcription, DNA-templated
  + 6 more...
.identical protein binding
.4-alpha-hydroxytetrahydrobiopterin dehydratase activity
.phenylalanine 4-monooxygenase activity
.transcription coactivator activity
.extracellular exosome
.cytosol
.cytoplasm
.nucleoplasm
21 EBI-739832,EBI-356900 SNRPF  
  .activation of mitophagy in response to mitochondrial depolarization
.ncRNA metabolic process
.mRNA 3'-end processing
  + 7 more...
.RNA binding .catalytic step 2 spliceosome
.SMN-Sm protein complex
.pICln-Sm protein complex
  + 10 more...
22 EBI-739832,EBI-437708 PPIA  
  .establishment of integrated proviral latency
.leukocyte migration
.positive regulation of protein secretion
  + 15 more...
.unfolded protein binding
.virion binding
.poly(A) RNA binding
  + 2 more...
.extracellular exosome
.membrane
.focal adhesion
  + 4 more...
23 EBI-739832,EBI-401755 GRB2  
  .positive regulation of reactive oxygen species metabolic process
.cellular response to ionizing radiation
.branching involved in labyrinthine layer morphogenesis
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.insulin receptor substrate binding
  + 6 more...
.Grb2-EGFR complex
.extracellular exosome
.vesicle membrane
  + 10 more...
24 EBI-739832,EBI-712344 PTS  
  .regulation of nitric-oxide synthase activity
.nitric oxide metabolic process
.small molecule metabolic process
  + 3 more...
.metal ion binding
.identical protein binding
.6-pyruvoyltetrahydropterin synthase activity
.cytosol
.mitochondrion
.cytoplasm
25 EBI-739832,EBI-745226 AIMP2  
  .Type II pneumocyte differentiation
.positive regulation of protein ubiquitination
.gene expression
  + 3 more...
.N/A .membrane
.cytosol
.nucleus
26 EBI-739832,EBI-538850 CIRBP  
  .mRNA stabilization
.positive regulation of translation
.stress granule assembly
  + 3 more...
.small ribosomal subunit rRNA binding
.poly(A) RNA binding
.translation repressor activity
  + 2 more...
.cytoplasmic stress granule
.cytoplasm
.nucleoplasm
.nucleus
27 EBI-739832,EBI-748492 EIF4H  
  .developmental growth
.cellular protein metabolic process
.sexual reproduction
  + 5 more...
.poly(A) RNA binding
.translation factor activity, RNA binding
.translation initiation factor activity
  + 2 more...
.perinuclear region of cytoplasm
.eukaryotic translation initiation factor 4F complex
.membrane
.cytosol
28 EBI-739832,EBI-711522 PAFAH1B3  
  .lipid catabolic process
.brain development
.nervous system development
  + 2 more...
.platelet-activating factor acetyltransferase activity
.identical protein binding
.1-alkyl-2-acetylglycerophosphocholine esterase activity
.extracellular exosome
.membrane
.cytosol
.cytoplasm
29 EBI-739832,EBI-358993 TRIP13  
  .regulation of nucleic acid-templated transcription
.oogenesis
.spermatid development
  + 8 more...
.identical protein binding
.ATP binding
.transcription cofactor activity
.nucleus
.male germ cell nucleus
30 EBI-739832,EBI-10242598 TRMT12  
  .tRNA processing .transferase activity .N/A
31 EBI-739832,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
32 EBI-739832,EBI-10244795 TBCEL  
  .N/A .N/A .cytoskeleton
.cytoplasm
33 EBI-739832,EBI-2549423 HMBOX1  
  .positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .cytoplasm
.nucleoplasm
.nucleus
34 EBI-739832,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
35 EBI-739832,EBI-10254507 LCLAT1  
  .glycerophospholipid biosynthetic process
.small molecule metabolic process
.cellular lipid metabolic process
  + 6 more...
.1-acylglycerol-3-phosphate O-acyltransferase activity .integral component of membrane
.membrane
.endoplasmic reticulum membrane
36 EBI-739832,EBI-948802 STAC2  
  .intracellular signal transduction .metal ion binding .N/A
37 EBI-739832,EBI-10181525 RUFY4  
  .N/A .metal ion binding .N/A
38 EBI-739832,EBI-9027502 KCTD1  
  .protein homooligomerization
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.transcription factor binding
.transcription corepressor activity
.nucleus
39 EBI-739832,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
40 EBI-739832,EBI-744506 FAM124A  
  .N/A .N/A .N/A
41 EBI-739832,EBI-10260328 CATSPERD  
  .sperm capacitation
.sperm-egg recognition
.multicellular organism reproduction
  + 4 more...
.N/A .sperm principal piece
.CatSper complex
.plasma membrane
42 EBI-739832,EBI-10172004 HOMEZ  
  .transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
43 EBI-739832,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
44 EBI-739832,EBI-1166928 ATPAF2  
  .proton-transporting ATP synthase complex assembly .N/A .nuclear speck
.mitochondrion
45 EBI-739832,EBI-2511344 KCTD6  
  .protein homooligomerization .ankyrin binding .N/A
46 EBI-739832,EBI-597063 ZCCHC10  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
47 EBI-739832,EBI-10274069 LGALS14  
  .positive regulation of T cell apoptotic process
.apoptotic process
.carbohydrate binding .nucleus
48 EBI-739832,EBI-8652459 METTL21A  
  .peptidyl-lysine methylation
.protein methylation
.ATPase binding
.Hsp70 protein binding
.protein-lysine N-methyltransferase activity
.cytoplasm
49 EBI-739832,EBI-747353 ATRIP  
  .DNA repair
.DNA replication
.DNA damage checkpoint
.K63-linked polyubiquitin binding .nucleoplasm
.nucleus
50 EBI-739832,EBI-3912424 POMGNT1  
  .protein O-linked glycosylation .beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity .integral component of membrane
.Golgi membrane
51 EBI-739832,EBI-359932 DPF2  
  .apoptotic signaling pathway
.apoptotic process
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.zinc ion binding
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.intracellular membrane-bounded organelle
.centrosome
.cytoplasm
  + 2 more...
52 EBI-739832,EBI-7405817 OSBP2  
  .lipid transport .cholesterol binding .membrane
53 EBI-739832,EBI-4401674 AIDA  
  .negative regulation of JNK cascade
.negative regulation of JUN kinase activity
.regulation of protein homodimerization activity
.dorsal/ventral pattern formation
.N/A .cytoplasm
54 EBI-739832,EBI-743117 CCDC101  
  .establishment of protein localization to chromatin
.histone H3 acetylation
.regulation of transcription, DNA-templated
  + 2 more...
.methylated histone binding .SAGA-type complex
.Ada2/Gcn5/Ada3 transcription activator complex
55 EBI-739832,EBI-7097057 CPNE2  
  .N/A .N/A .extracellular exosome
56 EBI-739832,EBI-359248 APIP  
  .regulation of ERK1 and ERK2 cascade
.small molecule metabolic process
.negative regulation of apoptotic process
  + 6 more...
.methylthioribulose 1-phosphate dehydratase activity
.identical protein binding
.zinc ion binding
.cytoplasm
57 EBI-739832,EBI-3916242 ACY3  
  .small molecule metabolic process
.viral process
.xenobiotic metabolic process
.metal ion binding
.hydrolase activity, acting on ester bonds
.aminoacylase activity
.extracellular exosome
.apical plasma membrane
.cytosol
58 EBI-739832,EBI-748896 MRFAP1L1  
  .N/A .identical protein binding .N/A
59 EBI-739832,EBI-741835 MAGEB18  
  .N/A .N/A .cytoplasm
60 EBI-739832,EBI-10173858 CCDC114  
  .outer dynein arm assembly .N/A .outer dynein arm
.cilium
61 EBI-739832,EBI-3918381 TSSK3  
  .intracellular signal transduction
.cell differentiation
.regulation of signal transduction
  + 3 more...
.ATP binding
.protein serine/threonine kinase activity
.magnesium ion binding
.cytoplasm
.nucleus
62 EBI-739832,EBI-10292696 CIB3  
  .N/A .calcium ion binding .N/A
63 EBI-739832,EBI-6658697 ALKBH3  
  .oxidative single-stranded DNA demethylation
.cell proliferation
.DNA dealkylation involved in DNA repair
.DNA repair
.cytosine C-5 DNA demethylase activity
.DNA-N1-methyladenine dioxygenase activity
.L-ascorbic acid binding
.ferrous iron binding
.mitochondrion
.cytoplasm
.nucleoplasm
.nucleus
64 EBI-739832,EBI-744593 MTMR9  
  .N/A .enzyme regulator activity .cytoplasm
65 EBI-739832,EBI-749162 INPP5K  
  .positive regulation of renal water transport
.negative regulation of glycogen (starch) synthase activity
.ruffle assembly
  + 35 more...
.inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
.inositol-1,4,5-trisphosphate 5-phosphatase activity
.inositol trisphosphate phosphatase activity
  + 7 more...
.perinuclear region of cytoplasm
.neuron projection
.ruffle membrane
  + 8 more...
66 EBI-739832,EBI-741350 THAP7  
  .negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.C2H2 zinc finger domain binding
.protein N-terminus binding
.metal ion binding
.DNA binding
.nuclear speck
.chromosome
67 EBI-739832,EBI-3924013 DCUN1D5  
  .N/A .N/A .N/A
68 EBI-739832,EBI-9675976 SNRNP25  
  .RNA splicing
.mRNA processing
.N/A .intercellular bridge
.cytoplasm
.U12-type spliceosomal complex
  + 2 more...
69 EBI-739832,EBI-1047273 ACAT2  
  .lipid metabolic process .acetyl-CoA C-acetyltransferase activity .extracellular exosome
.cytoplasm
.nucleolus
  + 2 more...
70 EBI-739832,EBI-750200 C1QTNF1  
  .positive regulation of aldosterone secretion
.negative regulation of platelet aggregation
.protein heterotrimerization
  + 7 more...
.collagen binding .integral component of plasma membrane
.extracellular space
.collagen trimer
71 EBI-739832,EBI-1044640 KRTAP9-2  
  .N/A .N/A .keratin filament
72 EBI-739832,EBI-10172511 KRTAP4-2  
  .N/A .N/A .keratin filament
73 EBI-739832,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
74 EBI-739832,EBI-1047335 ISCU  
  .protein maturation by iron-sulfur cluster transfer
.[2Fe-2S] cluster assembly
.small molecule metabolic process
  + 3 more...
.4 iron, 4 sulfur cluster binding
.2 iron, 2 sulfur cluster binding
.iron-sulfur transferase activity
  + 3 more...
.cytosol
.mitochondrial matrix
.mitochondrion
  + 2 more...
75 EBI-739832,EBI-4403434 GOLPH3L  
  .positive regulation of protein secretion
.Golgi organization
.phosphatidylinositol-4-phosphate binding .trans-Golgi network membrane
.Golgi cisterna membrane
.Golgi membrane
76 EBI-739832,EBI-6149062 MVB12B  
  .positive regulation of viral process
.ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
.regulation of epidermal growth factor receptor signaling pathway
  + 2 more...
.lipid binding .extracellular exosome
.vesicle
.late endosome membrane
  + 6 more...
77 EBI-739832,EBI-1378139 ROPN1  
  .small GTPase mediated signal transduction .N/A .cytoplasm
.nucleus
78 EBI-739832,EBI-740364 NEK6  
  .regulation of cellular senescence
.spindle assembly
.protein autophosphorylation
  + 13 more...
.protein kinase binding
.kinesin binding
.ATP binding
  + 3 more...
.nuclear speck
.microtubule
.cytosol
  + 4 more...
79 EBI-739832,EBI-739510 TRIM39  
  .positive regulation of apoptotic signaling pathway
.negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.protein ubiquitination
.apoptotic process
.identical protein binding
.ligase activity
.zinc ion binding
.cytosol
.mitochondrion
80 EBI-739832,EBI-752122 NXT2  
  .mRNA transport
.protein transport
.N/A .cytoplasm
.nucleus
81 EBI-739832,EBI-745730 ZFP64  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
82 EBI-739832,EBI-8638992 FAM118A  
  .N/A .N/A .integral component of membrane
83 EBI-739832,EBI-719790 FBXL12  
  .protein ubiquitination
.ubiquitin-dependent protein catabolic process
.N/A .cytoplasm
.ubiquitin ligase complex
84 EBI-739832,EBI-740924 PRR13  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .nucleus
85 EBI-739832,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
86 EBI-739832,EBI-372578 NAGK  
  .carbohydrate phosphorylation
.N-acetylneuraminate catabolic process
.N-acetylmannosamine metabolic process
.N-acetylglucosamine metabolic process
.N-acetylglucosamine kinase activity
.N-acylmannosamine kinase activity
.ATP binding
.extracellular exosome
87 EBI-739832,EBI-9057006 OSGIN1  
  .positive regulation of apoptotic process
.negative regulation of cell growth
.cell differentiation
.multicellular organismal development
.growth factor activity .N/A
88 EBI-739832,EBI-748356 DNPEP  
  .peptide metabolic process .zinc ion binding
.metallopeptidase activity
.aminopeptidase activity
.blood microparticle
.cytoplasm
.nucleoplasm
.nucleus
89 EBI-739832,EBI-352939 RUVBL2  
  .negative regulation of estrogen receptor binding
.transcriptional activation by promoter-enhancer looping
.cellular response to estradiol stimulus
  + 14 more...
.unfolded protein binding
.ATP-dependent 5'-3' DNA helicase activity
.identical protein binding
  + 7 more...
.MLL1 complex
.extracellular exosome
.NuA4 histone acetyltransferase complex
  + 10 more...
90 EBI-739832,EBI-1104564 MEMO1  
  .regulation of microtubule-based process .N/A .cytosol
.nucleus
91 EBI-739832,EBI-347416 LSM2  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
.RNA splicing
  + 2 more...
.poly(A) RNA binding
.Ral GTPase binding
.U6 snRNA binding
.catalytic step 2 spliceosome
.cytosol
.nucleoplasm
92 EBI-739832,EBI-744782 NME7  
  .left/right pattern formation
.ciliary receptor clustering involved in smoothened signaling pathway
.intraciliary transport
  + 6 more...
.metal ion binding
.ATP binding
.nucleoside diphosphate kinase activity
.ciliary basal body
.centrosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
brain82
connective tissue134
ear62
embryonic tissue9
heart11
intestine8
kidney14
lung14
mammary gland26
mouth181
muscle18
pancreas9
parathyroid48
pharynx24
placenta31
prostate36
testis29
thymus50
trachea19
uterus25
Health State
TissuesTPM*
normal39
breast (mammary gland) tumor32
gastrointestinal tumor8
germ cell tumor18
glioma9
head and neck tumor74
non-neoplasia31
soft tissue/muscle tissue tumor151
uterine tumor11
Developmental Stage
TissuesTPM*
adult27
embryoid body14
fetus70
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.5
adrenal gland2.1
appendix1.8
cerebral cortex17.4
colon7.6
duodenum10
esophagus26.6
gallbladder6
heart muscle7.4
kidney11.5
liver3.4
lung3.3
lymph node1.4
ovary1.6
pancreas7.8
placenta22.8
prostate6.3
salivary gland20.9
skin9.7
small intestine8.7
stomach8.7
testis5.4
thyroid gland19.4
urinary bladder6.9
Tissues
TissuesExpression level
appendixLow
breastLow
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonLow
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
fallopian tubeMedium
gallbladderMedium
heart muscleLow
hippocampusLow
kidneyLow
lateral ventricleLow
liverHigh
lungLow
lymph nodeHigh
nasopharynxMedium
pancreasMedium
placentaMedium
prostateMedium
salivary glandLow
seminal vesicleMedium
skin 2Low
small intestineMedium
spleenMedium
stomach 1Medium
stomach 2Low
testisLow
thyroid glandMedium
tonsilMedium
urinary bladderLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609732, gene) Ligand of numb protein x1; LNX1OMIM


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