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> Protein (NX_Q8TBZ8)
Protein (NX_Q8TBZ8)
Protein
Gene SymbolZNF564 to neXtProt (NX_Q8TBZ8)
DescriptionZinc finger protein 564
Chromosome19
Location19p13.2 (12636184 ~ 12662356) to Ensembl
Sequene Features : Isoforms 1, Variants 64, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 64 0
2014-09-19protein level
1 48 0
2014-05-27transcript level
1 48 0
2014-02-25transcript level
1 48 0
2013-12-09transcript level
1 38 0
2013-11-01transcript level
1 35 0
2013-09-12transcript level
1 35 0
2013-08-17transcript level
1 35 0
2013-07-15transcript level
1 17 0
2013-06-11transcript level
1 17 0
2013-02-12transcript level
1 7 0
2012-12-20transcript level
1 6 0
2012-10-30transcript level
1 9 0
2012-10-07transcript level
1 9 0
2012-08-24transcript level
1 4 0
2012-07-28transcript level
1 4 0
2012-06-08transcript level
1 4 0
2012-05-07transcript level
1 4 0
2012-04-10transcript level
1 4 0
2012-01-13transcript level
1 2 0
2011-12-20transcript level
1 2 0
2011-11-11transcript level
1 2 0
2011-08-23transcript level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TBZ8-1
25 0 10 63693.4026
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10273713,EBI-742268 TADA2A  
  .histone H3 acetylation
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.chromatin organization
.zinc ion binding
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.chromosome
.nucleus
.PCAF complex
2 EBI-10273713,EBI-748961 CCNDBP1  
  .regulation of cell cycle
.cell cycle
.N/A .cytoplasm
.nucleoplasm
.nucleus
3 EBI-10273713,EBI-740738 LDOC1  
  .negative regulation of cell proliferation .N/A .nucleolus
.nucleus
4 EBI-10273713,EBI-3905054 ALAS1  
  .small molecule metabolic process
.cellular lipid metabolic process
.mitochondrion organization
  + 4 more...
.pyridoxal phosphate binding
.5-aminolevulinate synthase activity
.mitochondrial matrix
.mitochondrion
.cytoplasm
.nucleoplasm
5 EBI-10273713,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
6 EBI-10273713,EBI-740978 MAGEA1  
  .negative regulation of Notch signaling pathway
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.histone deacetylase binding .plasma membrane
.cytoplasm
.nucleus
7 EBI-10273713,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
8 EBI-10273713,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
9 EBI-10273713,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
10 EBI-10273713,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
11 EBI-10273713,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
12 EBI-10273713,EBI-739674 CCDC85B  
  .negative regulation of transcription, DNA-templated
.negative regulation of fat cell differentiation
.negative regulation of cell growth
  + 2 more...
.N/A .centrosome
.cytoplasm
.nucleus
13 EBI-10273713,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
14 EBI-10273713,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
15 EBI-10273713,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
16 EBI-10273713,EBI-725997 TRIM41  
  .protein ubiquitination .ligase activity
.zinc ion binding
.cytoplasm
.nucleolus
17 EBI-10273713,EBI-10171416 CCDC136  
  .N/A .N/A .integral component of membrane
.mitochondrion
18 EBI-10273713,EBI-1050213 RPGRIP1  
  .retina development in camera-type eye
.response to stimulus
.eye photoreceptor cell development
.visual perception
.N/A .photoreceptor connecting cilium
.axoneme
19 EBI-10273713,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
20 EBI-10273713,EBI-349832 GOPC  
  .protein homooligomerization
.regulation of catalytic activity
.apical protein localization
  + 6 more...
.ion channel binding .postsynaptic membrane
.protein complex
.Golgi-associated vesicle membrane
  + 9 more...
21 EBI-10273713,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bone marrow20
brain7
cervix20
connective tissue6
embryonic tissue9
eye14
heart11
intestine43
kidney9
lung20
lymph22
mammary gland6
mouth45
pituitary gland60
placenta3
prostate5
skin9
spleen18
stomach20
testis6
thymus37
trachea19
uterus21
vascular58
Health State
TissuesTPM*
normal10
breast (mammary gland) tumor10
cervical tumor28
colorectal tumor71
gastrointestinal tumor8
germ cell tumor11
head and neck tumor22
leukemia21
lymphoma13
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor22
Developmental Stage
TissuesTPM*
adult9
embryoid body14
blastocyst16
fetus10
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.1
adrenal gland3.2
appendix3.6
bone marrow2.4
cerebral cortex2.1
colon6.2
duodenum5.1
esophagus3.8
gallbladder3.4
heart muscle3.6
kidney6.1
liver2
lung3.6
lymph node5.7
ovary4.8
pancreas1.1
placenta4
prostate4.7
salivary gland3
skin3.2
small intestine6.3
spleen4.8
stomach4.5
testis2.5
thyroid gland6.3
urinary bladder6.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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