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> Protein (NX_Q8TC92)
Protein (NX_Q8TC92)
Protein
Gene SymbolENOX1 to neXtProt (NX_Q8TC92)
DescriptionEcto-NOX disulfide-thiol exchanger 1
Chromosome13
Location13q14.11 (43787654 ~ 44361044) to Ensembl
Sequene Features : Isoforms 2, Variants 97, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.rhythmic process .oxidoreductase activity
.nucleic acid binding
.nucleotide binding
.plasma membrane
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 97 0
2014-09-19protein level
1 69 0
2014-05-27protein level
1 69 0
2014-02-25protein level
1 66 0
2013-12-09protein level
1 57 0
2013-11-01protein level
1 50 0
2013-09-12protein level
1 50 1
2013-08-17protein level
1 50 1
2013-07-15protein level
1 32 1
2013-06-11protein level
1 32 1
2013-02-12protein level
1 6 1
2012-12-20protein level
1 6 1
2012-10-30protein level
1 6 1
2012-10-07protein level
1 6 1
2012-08-24protein level
1 4 1
2012-07-28protein level
1 4 1
2012-06-08protein level
1 6 1
2012-05-07protein level
1 6 1
2012-04-10protein level
1 6 1
2012-01-13protein level
1 9 1
2011-12-20protein level
1 9 1
2011-11-11protein level
1 9 1
2011-08-23protein level
1 9 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TC92-1
12 9 1 73301.4944
NX_Q8TC92-2
0 9 1 27668.5228
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-713221,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
2 EBI-713221,EBI-10179508 ENOX2  
  .oxidation-reduction process
.regulation of growth
.cell growth
.ultradian rhythm
.protein disulfide oxidoreductase activity
.nucleic acid binding
.nucleotide binding
.external side of plasma membrane
.cytosol
.extracellular space
3 EBI-713221,EBI-2129899 TRIM43  
  .N/A .zinc ion binding .intracellular
4 EBI-713221,EBI-746595 ZMYND19  
  .N/A .metal ion binding .synapse
.plasma membrane
.cytoplasm
5 EBI-713221,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain19
embryonic tissue9
eye9
heart11
kidney18
liver9
lung11
lymph node11
pancreas4
placenta7
prostate5
skin4
testis43
uterus12
vascular19
Health State
TissuesTPM*
normal19
germ cell tumor22
glioma18
kidney tumor43
leukemia10
liver tumor20
lymphoma13
non-neoplasia10
primitive neuroectodermal tumor of the CNS15
skin tumor7
Developmental Stage
TissuesTPM*
adult10
fetus34
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.6
adrenal gland1.6
appendix3.6
cerebral cortex6.8
colon1.5
esophagus1.2
gallbladder2.3
heart muscle5.4
kidney3.2
lung1.3
lymph node2.9
ovary7.1
placenta3.6
prostate3.7
stomach1.4
testis10.6
urinary bladder4.3
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowHigh
breastMedium
bronchusHigh
cerebral cortexMedium
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusLow
kidneyMedium
lateral ventricleLow
liverLow
lungHigh
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
pancreasHigh
parathyroid glandMedium
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleMedium
skin 1High
skin 2Medium
small intestineHigh
smooth muscleMedium
soft tissue 1High
soft tissue 2High
stomach 1High
stomach 2High
testisLow
thyroid glandMedium
tonsilMedium
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610914, gene) Ecto-nox disulfide-thiol exchanger 1; ENOX1OMIM


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