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> Protein (NX_Q8TD30)
Protein (NX_Q8TD30)
Protein
Gene SymbolGPT2 to neXtProt (NX_Q8TD30)
DescriptionAlanine aminotransferase 2
Chromosome16
Location16q11.2 (46918290 ~ 46965209) to Ensembl
Sequene Features : Isoforms 2, Variants 49, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.small molecule metabolic process
.L-alanine catabolic process
.L-alanine metabolic process
  + 3 more...
.pyridoxal phosphate binding
.L-alanine:2-oxoglutarate aminotransferase activity
.mitochondrial matrix
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 49 4
2014-09-19protein level
2 42 4
2014-05-27protein level
2 42 4
2014-02-25protein level
2 42 4
2013-12-09protein level
2 30 4
2013-11-01protein level
2 30 4
2013-09-12protein level
2 30 1
2013-08-17protein level
2 30 1
2013-07-15protein level
2 22 1
2013-06-11protein level
2 22 1
2013-02-12protein level
2 7 2
2012-12-20protein level
2 10 2
2012-10-30protein level
2 10 2
2012-10-07protein level
2 10 1
2012-08-24protein level
2 10 1
2012-07-28protein level
2 10 1
2012-06-08protein level
2 11 1
2012-05-07protein level
2 8 1
2012-04-10protein level
2 8 1
2012-01-13protein level
2 7 1
2011-12-20protein level
2 7 1
2011-11-11protein level
2 7 1
2011-08-23protein level
2 7 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TD30-1
4 18 2 57866.2812
NX_Q8TD30-2
1 18 1 46952.409
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
ascites75
blood16
bone55
brain32
cervix41
ear186
embryonic tissue32
eye52
heart22
intestine56
kidney99
larynx42
liver121
lung35
lymph90
lymph node44
mammary gland79
mouth15
muscle122
ovary29
pancreas4
placenta21
prostate184
skin80
stomach52
testis22
thyroid21
tonsil117
trachea38
uterus51
vascular19
Health State
TissuesTPM*
normal42
breast (mammary gland) tumor53
cervical tumor57
chondrosarcoma24
colorectal tumor88
gastrointestinal tumor50
germ cell tumor49
glioma93
head and neck tumor14
kidney tumor87
leukemia84
liver tumor249
lung tumor48
lymphoma69
non-neoplasia31
ovarian tumor39
pancreatic tumor9
primitive neuroectodermal tumor of the CNS23
prostate cancer231
retinoblastoma86
soft tissue/muscle tissue tumor71
uterine tumor88
Developmental Stage
TissuesTPM*
adult46
embryoid body71
fetus32
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue43.1
adrenal gland8.6
appendix3.7
bone marrow3.2
cerebral cortex23.2
colon6.5
duodenum1.8
esophagus49
gallbladder9.3
heart muscle4.5
kidney26.4
liver51.6
lung2.1
lymph node5.3
ovary1.9
pancreas114
placenta2.7
prostate30.5
salivary gland34.8
skin35.4
small intestine2.4
spleen2.3
stomach28.1
testis16.2
thyroid gland7.4
urinary bladder3.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*138210, gene) Glutamate pyruvate transaminase 2; GPT2OMIM


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